Hepatoblastoma screening of low-birthweight children cost effective in US
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - May 31, 2020 Category: Drugs & Pharmacology Source Type: news

Mother ’s push to get a CT scan for her son reveals liver tumor 
Vincent Gonzaga Jr, five, of Hutchinson, Kansas, was diagnosed with hepatoblastoma, a cancer of the liver, a year after he began complaining of stomach pains, which was dismissed by doctors. (Source: the Mail online | Health)
Source: the Mail online | Health - January 2, 2019 Category: Consumer Health News Source Type: news

Parents close GoFundMe for son's liver transplant after discovering it will cost $1.1 MILLION  
Charlie Proctor, five, from Church, Lancashire, in the UK was diagnosed in February 2016 with hepatoblastoma, a rare tumor that begins in the liver usually during early childhood (Source: the Mail online | Health)
Source: the Mail online | Health - August 22, 2018 Category: Consumer Health News Source Type: news

Sodium Thiosulfate Post-Cisplatin May Lessen Hearing Loss
WEDNESDAY, June 27, 2018 -- Delayed administration of sodium thiosulfate after cisplatin chemotherapy may prevent treatment-related hearing loss in children with standard-risk hepatoblastoma without affecting survival outcomes, according to a study... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 27, 2018 Category: Pharmaceuticals Source Type: news

Otoprotectant Guards Against Cisplatin-Induced Hearing Loss Otoprotectant Guards Against Cisplatin-Induced Hearing Loss
Administration of a known otoprotectant following completion of cisplatin therapy reduces the incidence and severity of hearing loss associated with use of cisplatin in children treated for hepatoblastoma.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 21, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Study points to possible treatment target for aggressive liver cancer in kids
(Cincinnati Children's Hospital Medical Center) A protein in the cell nucleus already targeted therapeutically for several types of cancer has now been linked to an aggressive form of pediatric liver cancer called hepatoblastoma (HBL), according to a study published in the Nature journal Communications Biology. Scientists at Cincinnati Children's Hospital Medical Center report that laboratory testing indicates the protein, PARP1, may be an effective treatment target for the cancer, but emphasize additional research is needed to verify this. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 11, 2018 Category: Cancer & Oncology Source Type: news

Metabolism can be used to subtype hepatoblastoma
(Ecole Polytechnique F é d é rale de Lausanne) Looking at cell metabolism instead of histology, EPFL scientists have identified new biomarkers that could help more accurately classify the two main subtypes of hepatoblastoma, a children's liver cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 18, 2017 Category: Cancer & Oncology Source Type: news

In their own words: Six families share the impact of organ donation
This is the season for gratitude and giving, a time to celebrate friends, family, the end of one year and the beginning of a new one. But for a select group, it also is a time to celebrate one of the greatest gifts — the gift of life through organ donation. Mickey was born with a unique combination of congenital heart defects and spent most of his early life at Boston Children’s. He was one day shy of 6 months old when he received his heart transplant, and his family is grateful for every day since. “Mickey has shown us what courage and resiliency look like, and his transplant has taught us the true meaning of givin...
Source: Thrive, Children's Hospital Boston - January 5, 2016 Category: Pediatrics Authors: Michelle Higginson Tags: Diseases & Conditions Our Patients’ Stories double lung transplant heart transplant hepatoblastoma kidney transplant Liver transplant multivisceral transplant Pediatric Transplant Center (PTC) Source Type: news

Determination and Characterization of Tetraspanin-Associated Phosphoinositide-4 Kinases in Primary and Neoplastic Liver Cells
Accumulating evidence implicates phosphoinositide 4-phosphate as a regulatory molecule in its own right recruiting specific effector proteins to cellular membranes. Here, we describe biochemical and immunocytochemical methods to evaluate tetraspanin-associated phosphoinositide-4 kinases activity in primary human hepatic stellate cells (hHSC) and neoplastic hepatoblastoma cells. (Source: Springer protocols feed by Cell Biology)
Source: Springer protocols feed by Cell Biology - November 12, 2015 Category: Cytology Source Type: news

Medical News Today: Blastoma: Causes, Diagnosis and Treatments
Find out what blastoma is and about its numerous types such as neuroblastoma and hepatoblastoma. Also learn how blastomas are almost always treatable. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 28, 2015 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

Mexican teen battles metastatic cancer with his family by his side
His symptoms started two years ago while on a family vacation. Thirteen-year-old Manuel Sanchez Paniagua was increasingly tired, and his stomach hurt. His parents thought he must have caught a stomach bug on the trip, so when they got back to their home in Mexico City, they brought Manuel to the doctor. Unfortunately, it wasn’t just a stomach bug. Physicians told the family that Manuel had a rare cancerous tumor in his liver called hepatoblastoma. When they went in to biopsy the tumor to confirm the diagnosis, they accidentally caused severe internal bleeding, and Manuel ended up in the ICU for a week. A second opinion O...
Source: Thrive, Children's Hospital Boston - September 15, 2015 Category: Pediatrics Authors: Jenny Fernandez Tags: Cancer Our patients’ stories Carlos Rodriguez-Galindo Heung Bae Kim Source Type: news

Sodium Thiosulfate Post - Cisplatin May Lessen Hearing Loss
Children with hepatoblastoma on cisplatin less likely to have hearing loss with sodium thiosulfate added (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - November 11, 2014 Category: Cancer & Oncology Tags: Gastroenterology, Oncology, ENT, Pediatrics, Pharmacy, Journal, Source Type: news

Effect of chemotherapy on surgical resection of liver tumors
A study of pediatric patients with hepatoblastoma suggests an opportunity to reduce chemotherapy in up to 65 percent of patients, which could lead to a decrease in the incidence of adverse effects, experts say. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 31, 2014 Category: Science Source Type: news

Dramatic Survival Gain in Kids With High-Risk HepatoblastomaDramatic Survival Gain in Kids With High-Risk Hepatoblastoma
Dose-dense administration of cisplatin, the most efficacious chemotherapy in this setting, boosted outcomes. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 15, 2013 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Hematology and Oncology: Images in Clinical Medicine
Editor: V. Dimov, M.D., Assistant Professor at University of ChicagoDisseminated Cryptococcosis in a CLL patient. NEJM, 05/2014.Leukemia cutis. Lancet, 10/2012.Biliary ileus. Lancet, 07/2012.Corneal snowflakes due to IgG-kappa multiple myeloma. Lancet, 08/2012.Splenic Spirals due to hepatoblastoma. NEJM, 06/2012.Hypertrophic Pulmonary Osteoarthropathy and Tripe Palms due to lung cancer. NEJM, 01/2012.Metastasis of Renal-Cell Carcinoma. NEJM, 10/2011.Amelanotic choroidal melanoma. Lancet, 03/2011.Retroperitoneal liposarcoma with lamellar bone inside.A painful cranial bulge. Lancet, 05/2011.Splenic Calcification in sick...
Source: Clinical Cases and Images - August 22, 2009 Category: General Medicine Tags: Hematology Images Oncology Source Type: news