Parents close GoFundMe for son's liver transplant after discovering it will cost $1.1 MILLION  

Charlie Proctor, five, from Church, Lancashire, in the UK was diagnosed in February 2016 with hepatoblastoma, a rare tumor that begins in the liver usually during early childhood
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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CONCLUSIONS: SRFA is an effective minimal-invasive treatment option in pediatric patients with liver tumors of different etiologies. PMID: 32954876 [PubMed - in process]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
CONCLUSIONS: When the predictive remnant liver volume by computed tomography-volumetry before extended hepatectomy for patients with hepatoblastoma is less than 40%, the possibility of posthepatectomy liver failure should be recognized. PMID: 32799783 [PubMed - as supplied by publisher]
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - Category: Transplant Surgery Authors: Tags: Exp Clin Transplant Source Type: research
Liver transplantation (LT) for unresectable colorectal liver metastases has long been abandoned because of dismal prognoses. After the dark ages, advances in chemotherapy and diagnostic imaging have enabled strict patient selection, and the pioneering study from the Oslo group has contributed to the substantial progress in this field. For unresectable neuroendocrine liver metastases, LT for patients who met the Milan criteria was able to achieve excellent long-term outcomes. The guidelines further adopted in the United States and Europe were based on these criteria. For hepatoblastoma, patients with unresectable and border...
Source: Transplantation - Category: Transplant Surgery Tags: Reviews Source Type: research
n Ranganathan Unresectable hepatocellular carcinoma (HCC) was first removed successfully with total hepatectomy and liver transplantation (LT) in a child over five decades ago. Since then, children with unresectable liver cancer have benefitted greatly from LT and a confluence of several equally important endeavors. Regional and trans-continental collaborations have accelerated the development and standardization of chemotherapy regimens, which provide disease control to enable LT, and also serve as a test of unresectability. In the process, tumor histology, imaging protocols, and tumor staging have also matured to bet...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Conclusion: Survivors of hepatoblastoma are at risk for long-term complications. They require long-term monitoring for late effects.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
Marco Spada Approximately 20% of children with hepatoblastoma (HB) have metastatic disease at diagnosis, most frequently in the lungs. In children with HB, lung metastatic disease is associated with poorer prognosis. Its treatment has been approached with a variety of methods that integrate chemotherapy and surgical resection. The timing and feasibility of complete extirpation of lung metastases, by chemotherapy and/or metastasectomy, is crucial for the surgical treatment of the primary liver tumor, which can vary from major hepatic resections to liver transplantation (LT). In children with unresectable HB, which can...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
ushi Fuchimoto Yuko Kitagawa Tatsuo Kuroda The curability of chemotherapy-resistant hepatoblastoma (HB) largely depends on the achievement of radical surgical resection. Navigation techniques utilizing indocyanine green (ICG) are a powerful tool for detecting small metastatic lesions. We herein report a patient who underwent a second living donor liver transplantation (LDLTx) for multiple recurrent HBs in the liver graft following metastasectomy for peritoneal dissemination with ICG navigation. The patient initially presented with ruptured HB at 6 years of age and underwent 3 liver resections followed by the first ...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Case Report Source Type: research
Purpose of review Hepatoblastoma is the most common primary pediatric liver malignancy. The goal of treatment in hepatoblastoma is complete surgical resection. Recently published multinational collaborative studies are better defining risk factors for disease recurrence and guide optimal treatment strategy. Recent findings Successful margin-negative resection of hepatoblastoma is dependent on the location and extent of disease as defined by the PRETEXT classification. Liver transplantation is an appropriate treatment modality when complete oncological resection requires total hepatectomy. In general, advanced PRETEXT ...
Source: Current Opinion in Organ Transplantation - Category: Surgery Tags: LIVER TRANSPLANTATION: Edited by Sophoclis P. Alexopoulos Source Type: research
Publication date: Available online 28 February 2019Source: Hepatobiliary &Pancreatic Diseases InternationalAuthor(s): Samuele Iesari, Milton Eduardo Inostroza Núñez, Juan Manuel Rico Juri, Olga Ciccarelli, Eliano Bonaccorsi-Riani, Laurent Coubeau, Pierre-François Laterre, Pierre Goffette, Chantal De Reyck, Benoît Lengelé, Pierre Gianello, Jan LerutAbstractBackground: Liver transplantation is the treatment for end-stage liver diseases and well-selected malignancies. The allograft shortage may be alleviated with living donation. The initial UCLouvain experience of adult living-donor live...
Source: Hepatobiliary and Pancreatic Diseases International - Category: Gastroenterology Source Type: research
Multifocal hepatoblastoma (HB) is often treated with total hepatectomy and transplantation owing to concerns of surgical resectability, local recurrence, and/or metachronous tumor in the remnant liver. We aimed to review HB patients to determine the risk of local recurrence in multifocal disease.
Source: Journal of Pediatric Surgery - Category: Surgery Authors: Source Type: research
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