B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
Conditions:   Pediatric Solid Tumor;   Germ Cell Tumor;   Retinoblastoma;   Hepatoblastoma;   Wilms Tumor;   Rhabdoid Tumor;   Carcinoma;   Osteosarcoma;   Ewing Sarcoma;   Rhabdomyosarcoma;   Synovial Sarcoma;   Clear Cell Sarcoma;   Malignant Peripheral Nerve Sheath Tumors;   Desm oplastic Small Round Cell Tumor;   Soft Tissue Sarcoma;   Neuroblastoma;   Melanoma Interventions:   Biological: second generation 4-1BBζ B7H3-EGFRt-DH...
Source: ClinicalTrials.gov - July 23, 2020 Category: Research Source Type: clinical trials

A Randomized Multi-institutional Study of Sodium Thiosulfate as Auditory Protection for Children With Hepatoblastoma
Condition:   Hepatoblastoma Intervention:   Drug: Sodium Thiosulfate Injection Sponsors:   Shanghai Children's Medical Center;   Children's Hospital of Fudan University;   Shanghai Children's Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 20, 2020 Category: Research Source Type: clinical trials

Flavored, Oral Irinotecan (VAL-413) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors
Conditions:   Solid Tumors;   Neuroblastoma;   Rhabdomyosarcoma;   Ewing Sarcoma;   Hepatoblastoma;   Medulloblastoma Interventions:   Drug: VAL-413;   Drug: Temozolomide Sponsor:   Valent Technologies, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 7, 2020 Category: Research Source Type: clinical trials

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial
Conditions:   Hematopoietic and Lymphoid Cell Neoplasm;   Recurrent Ependymoma;   Recurrent Ewing Sarcoma;   Recurrent Hepatoblastoma;   Recurrent Histiocytic and Dendritic Cell Neoplasm;   Recurrent Langerhans Cell Histiocytosis;   Recurrent Lymphoma;   Recurrent Malignant Germ Cel l Tumor;   Recurrent Malignant Glioma;   Recurrent Malignant Solid Neoplasm;   Recurrent Medulloblastoma;   Recurrent Neuroblastoma;   Recurr...
Source: ClinicalTrials.gov - March 25, 2020 Category: Research Source Type: clinical trials

Yttrium-90 (TARE-Y90) in Children, Adolescents, and Young Adults With Liver Tumors
Conditions:   Hepatoblastoma;   Hepatocellular Carcinoma;   Rhabdoid Tumor of Liver;   Undifferentiated (Embryonal) Sarcoma of the Liver;   Pediatric Liver Cancer;   Liver Tumors Interventions:   Behavioral: Quality of Life Assessment;   Radiation: Transarterial Radioembolization Sponsors:   Nemours Children's Clinic;   Alfred I. duPont Hospital for Children Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2020 Category: Research Source Type: clinical trials