Medical News Today: Blastoma: Causes, Diagnosis and Treatments

Find out what blastoma is and about its numerous types such as neuroblastoma and hepatoblastoma. Also learn how blastomas are almost always treatable.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Cancer / Oncology Source Type: news

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CONCLUSION: Overall, this meta-analysis has demonstrated for the first time that LINC00673 rs11655237 could increase susceptibility to cancer. PMID: 32650095 [PubMed - as supplied by publisher]
Source: Genomics - Category: Genetics & Stem Cells Authors: Tags: Genomics Source Type: research
Publication date: April 2020Source: Cancer Epidemiology, Volume 65Author(s): Julie Volk, Julia E. Heck, Kjeld Schmiegelow, Johnni HansenAbstractBackgroundParental occupational exposures are suggested as contributing causes of childhood cancer.MethodsChildren age
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
AbstractAbdominal tumors (AT) in children account for approximately 17% of all pediatric solid tumor cases, and frequently exhibit embryonal histological features that differentiate them from adult cancers. Current molecular approaches have greatly improved the understanding of the distinctive pathology of each tumor type and enabled the characterization of novel tumor biomarkers. As seen in abdominal adult tumors, microRNAs (miRNAs) have been increasingly implicated in either the initiation or progression of childhood cancer. Moreover, besides predicting patient prognosis, they represent valuable diagnostic tools that may...
Source: Cancer and Metastasis Reviews - Category: Cancer & Oncology Source Type: research
AbstractPediatric solid tumors have long been known to shed tumor cells, DNA, RNA, and proteins into the blood. Recent technological advances have allowed for improved capture and analysis of these typically scant circulating materials. Efforts are ongoing to develop “liquid biopsy” assays as minimally invasive tools to address diagnostic, prognostic, and disease monitoring needs in childhood cancer care. Applying these highly sensitive technologies to serial liquid biopsies is expected to advance understanding of tumor biology, heterogeneity, and evolution over the course of therapy, thus opening new avenues f...
Source: Cancer and Metastasis Reviews - Category: Cancer & Oncology Source Type: research
Publication date: Available online 8 March 2019Source: Surgery (Oxford)Author(s): Emma SidebothamAbstractWhile all childhood cancers are rare, the abdomen and pelvis are common sites of origin. After haematological malignancies and intracranial tumours, neuroblastoma is the most common childhood cancer, most often arising in the adrenal gland. The next most common extracranial tumours are Wilms tumour, arising in the kidney (nephroblastoma) and rhabdomyosarcoma that may arise in a variety of sites, typically in the pelvis. Hepatoblastoma, non-Hodgkin lymphoma and germ cell tumours are other abdominal and pelvic tumours see...
Source: Surgery (Oxford) - Category: Surgery Source Type: research
Conclusion We observed increased risks of CNS tumors in offspring after parental employment in painting and printing industries. Children of fathers employed in painting and printing industries had a two-fold increase in AML. PMID: 30838423 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Work, Environment and Health - Category: Occupational Health Authors: Tags: Scand J Work Environ Health Source Type: research
Conclusions: Extracranial and extraosseous pediatric solid tumors include a wide range of tumors with a predilection for male sex and children below 4 years of age. Soft tissue tumors, neuroblastoma, and renal tumors are the most common; the outcomes of Wilms tumor and hepatoblastoma are favorable.
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSION: Increasing incidence trends for all cancers and selected malignancies are consistent with those reported in other developed countries, and may reflect the changes in demographics and etiological exposures, and artefacts of changes in cancer coding, diagnosis and reporting. Significant decreasing trend for astrocytoma in late childhood was observed for the first time. PMID: 29537768 [PubMed - in process]
Source: Health Promotion and Chronic Disease Prevention in Canada - Category: International Medicine & Public Health Tags: Health Promot Chronic Dis Prev Can Source Type: research
Danysh The environmental determinants of pediatric embryonal tumors remain unclear. Because of the growing concern over the impact of exposures to traffic-related air pollution on pediatric cancer, we conducted a population-based study evaluating the impact of maternal residential proximity to major roadways on the risk of pediatric embryonal tumors in offspring. We identified children diagnosed with neuroblastoma, Wilms tumor, retinoblastoma, or hepatoblastoma at <5 years of age from the Texas Cancer Registry and selected unaffected controls from birth certificates. Two residential proximity measures were used...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
The National Cancer Institute seeks parties to license human monoclonal antibodies and immunoconjugates and co-develop, evaluate, and/or commercialize large-scale antibody production and hepatocellular carcinoma (HCC) xenograft mouse models.IC: NCINIH Ref. No.: E-130-2011Advantages: Monoclonal antibodies create a level of specificity that can reduce deleterious side-effectsMultiple treatment strategies available including the killing of cancer cells with a toxic agent or by inhibiting cell signalingNon-invasive and potentially non-liver toxic alternative to current HCC treatment strategiesApplications: ...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
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