Antimicrobial fibres derived from aryl-diazonium conjugation of chitosan with Harakeke (Phormium tenax) and Hemp (Cannabis sativa) Hurd
This study reports aryl-diazonium covalent attachment of chitosan and PD13 (6-O-(3-(2-(N,N-dimethylamino)ethylamino)-2-hydroxypropyl)chitosan), a chitosan derivative with improved antibacterial activity, on to PTF and HH. The modification was confirmed using FTIR, XPS, SEM and water contact angle studies. Comparison of aryl-diazonium versus the use of succinic anhydride bridging for chitosan attachment was also investigated, with the diazonium method giving improved results. The treated PTF and HH fibres had good antibacterial activity against Staphylococcus aureus and this study contributes to the development of sustainab...
Source: International Journal of Biological Macromolecules - March 28, 2024 Category: Biochemistry Authors: Delsa Pulickal Joseph Urawadee Rajchakit Lisa I Pilkington Vijayalekshmi Sarojini David Barker Source Type: research
HemU and TonB1 contribute to hemin acquisition in Stenotrophomonas maltophilia
ConclusionHemA, HemU, and TonB1 contribute to hemin acquisition in S. maltophilia. Fur represses the expression of hemA and hemU in iron-replete conditions. HemA expression is regulated by low iron levels, and HemP acts as a negative regulator of this regulatory circuit. HemU expression is regulated by low iron and hemin levels in a hemP-dependent manner. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 26, 2024 Category: Microbiology Source Type: research
Valorisation of industrial hemp residue from essential oil production by recovery of cannabidiol and chemo-enzymatic conversion to cannabielsoin
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Daniele Fiorito, Davide Tessaro, Fabio Sangalli, Celeste Nobbio, Mario Nebuloni, Matteo Vezzini, Elisabetta Brenna, Fabio Parmeggiani The production of essential oils by steam distillation is invariably associated with large amounts of organic waste which is normally disposed of or returned to the fields, although it may... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Green Chem. latest articles)
Source: RSC - Green Chem. latest articles - March 20, 2024 Category: Chemistry Authors: Daniele Fiorito Source Type: research
Anti-proliferative and apoptotic effect of cannabinoids on human pancreatic ductal adenocarcinoma xenograft in BALB/c nude mice model
In this study, the anti-proliferative and apoptotic effect of cannabinoid solution (THC:CBD at 1:6) at a dose of 1, 5, and 10 mg/kg body weight compared to the negative control (sesame oil) and positive control (5-fluorouracil) was investigated in human PDAC xenograft nude mice model. The findings showed that cannabinoids significantly decreased the mitotic cells and mitotic/apoptotic ratio, meanwhile dramatically increased the apoptotic cells. Parallelly, cannabinoids significantly downregulated Ki-67 and PCNA expression levels. Interestingly, cannabinoids upregulated BAX, BAX/BCL-2 ratio, and Caspase-3, meanwhile, downre...
Source: Cancer Control - March 19, 2024 Category: Cancer & Oncology Authors: Trung Quang Le Nuntana Meesiripan Suleeporn Sanggrajang Nuntakan Suwanpidokkul Piyaporn Prayakprom Chatchada Bodhibukkana Vipada Khaowroongrueng Kankanit Suriyachan Somchai Thanasitthichai Attasit Srisubat Pattamaporn Surawongsin Anudep Rungsipipat Siriwa Source Type: research
The Public Health Challenge of Δ 8 -THC and Derived Psychoactive Cannabis Products
This study is a reminder that there is a diverse set of cannabis products on the market that vary in their legal and regulatory status and potential for harm. Δ8-THC is a psychoactive cannabinoid that can be derived fr om hemp. It was introduced to the retail market in 2018 and there are indications that its use is on the rise. There is little regulatory oversight of production and sales of Δ8-THC and some evidence of adverse outcomes after use. (Source: JAMA)
Source: JAMA - March 12, 2024 Category: General Medicine Source Type: research
Exploring the Diverse Biological Properties of Cannabidiol: A Focus on Plant Growth Stimulation
Chem Biodivers. 2024 Mar 11:e202400274. doi: 10.1002/cbdv.202400274. Online ahead of print.ABSTRACTThe aim of the current study was to compare some biological activities of edible oils enriched with 10% of cannabidiol (CBD samples) from the Slovak market. In addition, hemp, coconut, argan, and pumpkin pure oils were also examined. The study evaluated the fatty acids content, as well as antibacterial, antifungal, antioxidant, cytotoxic, and phytotoxic activities. The CBD samples presented antimicrobial activity against the tested bacterial strains at higher concentrations (10000 and 5000 mg/L) and antifungal activity agains...
Source: Chemistry and Biodiversity - March 11, 2024 Category: Biochemistry Authors: Daniela Gru ľová Be áta Baranová Rosaria Francolino Hazem Elshafie Zuzana Ki ššová Al žbeta Glovaťáková Laura De Martino Giuseppe Amato Mara Martino Lucia Caputo Flavio Polito Francesco Manna Ippolito Camele Ľudmila Tkáčiková Vincenzo De Fe Source Type: research
Investigation on the presence of mycotoxins in seed hemp varieties
. (Source: Food Additives and Contaminants Part A)
Source: Food Additives and Contaminants Part A - February 26, 2024 Category: Food Science Authors: Chiara LanzanovaPaola GiorniGiulia BullaSabrina LocatelliMassimo MontanariIlaria AlbertiGiulia LeniAlessio AbateTerenzio Bertuzzia CREA Research Centre for Cereal and Industrial Crops, Bergamo, Italyb Department of Sustainable Crop Production – DIPROVES Source Type: research
Separation of lignin derivatives from hemp fiber using supercritical CO < sub > 2 < /sub > , ethanol, and water at different temperatures
Int J Biol Macromol. 2024 Feb 23:130390. doi: 10.1016/j.ijbiomac.2024.130390. Online ahead of print.ABSTRACTThe process of lignin extraction often involves intricate chemical transformations, influencing its potential for high-value utilization. By investigating the process of lignin derivatives extraction from hemp fibers using supercritical CO2, ethanol, and water, we identified the relationship between the chemical structure of lignin derivatives and temperature. This discovery contributes to controlling the chemical structure of lignin derivatives through temperature modulation. We observed that lignin derivatives extr...
Source: International Journal of Biological Macromolecules - February 25, 2024 Category: Biochemistry Authors: Yunhao Zhang Huan Chen Hang Sun Zengquan Liu Bo Lei Bo Wu Yanhong Feng Source Type: research
Multifunctional coatings fabricated from Chinese hemp-derived superhydrophobic micro-nanocellulose
Int J Biol Macromol. 2024 Feb 23:130430. doi: 10.1016/j.ijbiomac.2024.130430. Online ahead of print.ABSTRACTEcologically feasible strategies for constructing superhydrophobic surfaces offer versatile applications in waterproofing, self-cleaning, selective absorption, and corrosion protection. Herein, we prepared low-surface-energy branched-chain-enriched micronanorod (F@SiO2@MNC) by hydrolyzing silane coupling agent and modifying fluoropolymer using micro-nanocellulose extracted from waste straw (Chinese hemp). These rods were sprayed and adhered to various substrates precoated with a binder, resulting in superhydrophobic ...
Source: International Journal of Biological Macromolecules - February 25, 2024 Category: Biochemistry Authors: Yibin Feng Tiantian Xu Xiaojin Shi Yang Hu Chunlin Ni Zhuangzhuang Chu Zhuohong Yang Source Type: research
Separation of lignin derivatives from hemp fiber using supercritical CO < sub > 2 < /sub > , ethanol, and water at different temperatures
Int J Biol Macromol. 2024 Feb 23:130390. doi: 10.1016/j.ijbiomac.2024.130390. Online ahead of print.ABSTRACTThe process of lignin extraction often involves intricate chemical transformations, influencing its potential for high-value utilization. By investigating the process of lignin derivatives extraction from hemp fibers using supercritical CO2, ethanol, and water, we identified the relationship between the chemical structure of lignin derivatives and temperature. This discovery contributes to controlling the chemical structure of lignin derivatives through temperature modulation. We observed that lignin derivatives extr...
Source: International Journal of Biological Macromolecules - February 25, 2024 Category: Biochemistry Authors: Yunhao Zhang Huan Chen Hang Sun Zengquan Liu Bo Lei Bo Wu Yanhong Feng Source Type: research
Multifunctional coatings fabricated from Chinese hemp-derived superhydrophobic micro-nanocellulose
Int J Biol Macromol. 2024 Feb 23:130430. doi: 10.1016/j.ijbiomac.2024.130430. Online ahead of print.ABSTRACTEcologically feasible strategies for constructing superhydrophobic surfaces offer versatile applications in waterproofing, self-cleaning, selective absorption, and corrosion protection. Herein, we prepared low-surface-energy branched-chain-enriched micronanorod (F@SiO2@MNC) by hydrolyzing silane coupling agent and modifying fluoropolymer using micro-nanocellulose extracted from waste straw (Chinese hemp). These rods were sprayed and adhered to various substrates precoated with a binder, resulting in superhydrophobic ...
Source: International Journal of Biological Macromolecules - February 25, 2024 Category: Biochemistry Authors: Yibin Feng Tiantian Xu Xiaojin Shi Yang Hu Chunlin Ni Zhuangzhuang Chu Zhuohong Yang Source Type: research
Development and Validation of a GC-FID Method for the Quantitation of Δ
8-Tetrahydrocannabinol and Impurities Found in Synthetic Δ
8-Tetrahydrocannabinol and Vaping Products
In this study, a gas chromatography-flame ionization detection method was developed and validated for the determination of delta-8-tetrahydrocannabinol and some of its impurities (recently published) found in synthesized trans-delta-8-tetrahydrocannabinol raw material and included olivetol, cannabicitran, Δ
8-cis-iso-tetrahydrocannabinol, Δ
4-iso-tetrahydrocannabinol, iso-tetrahydrocannabifuran, cannabidiol, Δ
4,8-iso-tetrahydrocannabinol, Δ
8-iso-tetrahydrocannabinol,
4,8-epoxy-iso-tetrahydrocannabinol, trans-Δ
9-tetrahydrocannabinol, 8-hydroxy-iso-THC, 9α-hydroxyhexahydrocannabinol, an...
Source: Planta Medica - February 22, 2024 Category: Drugs & Pharmacology Authors: Gul, Waseem Shahzadi, Iram Sarma, Nandakumara Kim, Nam-Cheol ElSohly, Mahmoud A. Tags: Original Papers Source Type: research
Molecules, Vol. 29, Pages 921: Development of Pure Certified Reference Material of Cannabidiol
Dunming Xu
Cannabidiol (CBD) is the major functional component in hemp and has a broad range of pharmacological applications, such as analgesic, anti-epileptic, anti-anxiety, etc. Currently, CBD is widely used in pharmaceuticals, cosmetics, and food. To ensure the quality and safety of the products containing CBD, more and more related sample testing is being conducted, and the demand for CBD-certified reference material (CRM) has also sharply increased. However, there is currently a lack of relevant reference materials. In this paper, a simple method for preparing CBD CRM was established based on preparative liquid c...
Source: Molecules - February 20, 2024 Category: Chemistry Authors: Congcong Yu Ruihan Long Feng Cao Xinying Zhao Tao Lan Dunming Xu Tags: Article Source Type: research
Molecules, Vol. 29, Pages 899: Efficient Capture of Cannabis Terpenes in Olive Oil during Microwave-Assisted Cannabinoid Decarboxylation
votto
The development of selective extraction protocols for Cannabis-inflorescence constituents is still a significant challenge. The characteristic Cannabis fragrance can be mainly ascribed to monoterpenes, sesquiterpenes and oxygenated terpenoids. This work investigates the entrapment of Cannabis terpenes in olive oil from inflorescences via stripping under mild vacuum during the rapid microwave-assisted decarboxylation of cannabinoids (MW, 120 &deg;C, 30 min) and after subsequent extraction of cannabinoids (60 and 100 &deg;C). The profiles of the volatiles collected in the oil samples before and afte...
Source: Molecules - February 18, 2024 Category: Chemistry Authors: Luisa Boffa Arianna Binello Giancarlo Cravotto Tags: Article Source Type: research
Molecules, Vol. 29, Pages 791: Nutritionally Valuable Components and Heat-Induced Contaminants in Extruded Snack Products Enriched with Defatted Press Cakes
Šubarić
This research studies the influence of the addition of defatted press cakes (from the production of hazelnut, camelina, pumpkin, and hemp seed oil) on nutritionally important components: fibre, resistant starch, polyphenols, hydroxymethylfurfural (HMF), and acrylamide in directly and indirectly expanded snacks. The amounts of press cakes added to corn grits were 3, 6, and 9%. Extrusion was carried out in a laboratory single-screw extruder. For indirectly expanded products (SCFX), supercritical CO2 was injected during extrusion, and secondary expansion was completed in the microwave oven. The type and content...
Source: Molecules - February 8, 2024 Category: Chemistry Authors: Antun Jozinovi ć Jelena Panak Balenti ć Đurđica Ačkar Mirta Ben šić Jurislav Babi ć Veronika Bari šić Ante Lon čarić Borislav Mili čević Drago Šubarić Tags: Article Source Type: research
