Explanted Lung Cancer Identified During Lung Transplant: A Linked Analysis of the SRTR and the NCDB
This study seeks to evaluate LCoE outcomes to better understand the prognostic implications of a malignancy in lung transplant candidates. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J. Diaz Martinez, M. De Perrot, M. Cypel, S. Keshavjee, R. Mamidi Reddy, E. Wakeam Source Type: research

The Presence of Cold Agglutinins in Recipients is a Risk Factor for Severe Primary Graft Dysfunction After Lung Transplantation
Purpose: The relevance of the presence of cold agglutinins in lung transplantation recipients (LTx) is unclear. Cold agglutinin disease usually presents with hemolytic anemia but may also contribute to the onset of pulmonary embolisms caused by cold-reacting autiantibodies. While there is usually no hypothermia, the new lungs are still cold during implantation. The aim of this study is to analyze the impact of cold agglutinins in lung transplant recipients on short- and long-term outcome after LTx. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Semmelmann, D. Schibilsky, J. Kalbhenn, F. Emmerich Source Type: research

Primary Graft Dysfunction: Shifting from Static Grading to Temporal Classification
Purpose: Primary Graft Dysfunction (PGD) is an umbrella term that encompasses different pathophysiological mechanisms leading to lung edema in the early stages after lung transplantation (LTx). Current PGD grading is based on the assessment at fixed timepoints within the first 72 hours post-LTx, and this static grading does not reflect the underlying disease patterns resulting in PGD. Therefore, we propose a temporal PGD classification aiming to capture the dynamic evolution of PGD severity over time. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J. Van Slambrouck, A. Khan, C. Vandervelde, C. Vanluyten, X. Jin, A. Barbarossa, J. Kaes, L. Schoonjans, R. Vos, D. Van Raemdonck, P. Carmeliet, L. Ceulemans Source Type: research

UK Experience of Direct Procurement of Lungs with Ongoing Abdominal Normothermic Regional Perfusion from Controlled DCD Donors
Purpose: Describe the UK experience of direct retrieval and preservation (DRP) of lungs for transplantation alongside abdominal normothermic regional perfusion (A-NRP), with an analysis of early outcomes for lungs transplanted with this method compared to standard retrieval after circulatory death (DCD). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , R. Hogg, S. Beale, A. Jothidasan, M. Husain, J. Dunning, B. Zych, P. Kaul, S. Tsui, A. Al Adhami, J. Parmar, P. Curry, S. Messer, P. Mohite, R. Venkateswaran, V. Mehta, G. Meachery, B. Ramesh, J. Mascaro, D. Quinn, B. Raj, R. Sutcliffe, S. Dharmic, C. J Source Type: research

Comparison of Perioperative Outcomes Between Living-Donor Lobar Lung Transplant Versus Deceased-Donor Lung Transplant
This study aims to compare perioperative and early post-transplant outcomes between LDLLT and deceased-donor lung transplantation (DDLT). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , D. Nakajima, M. Takahashi, S. Tanaka, Y. Yutaka, A. Ohsumi, H. Date Source Type: research

Does Ex Vivo Lung Perfusion Mitigate the Detrimental Effects of Primary Graft Dysfunction? A Propensity Matched Analysis of the United Network for Organ Sharing Database
Purpose: Previous studies and anecdotal reports have proposed that recipients who develop primary graft dysfunction grade 3 (PGD3) following lung transplantation from allografts that underwent ex vivo lung perfusion (EVLP) have improved outcomes, as compared to those who did not undergo EVLP. We sought to determine if this held true in a national database. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , E.Y. Cui, D. Satija, M.C. Henn, C.T. Walk, K. Choi, V. Ramsammy, N.A. Mokadam, A.M. Ganapathi, B.A. Whitson Source Type: research

Prevalence, Risk Factors and Prognosis of Bronchial Dehiscence After Lung Transplantation. A 10 Years Single Center Study
Purpose: Bronchial ischemia is common after lung transplantation (LT) and may lead to airway complications such as dehiscence (DH). However, few studies assess its incidence using MDS and/or ISHLT classifications (1). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: M. Spaes, C. Landais, F. Gonin, T. Ngo, D. Usturoi, M. Glorion, J. De Wolf, C. Pricopi, F. Parquin, E. Cuquemelle, O. Brugiere, A. Vallee, J. Messika, A. Roux, E. Sage, Source Type: research

Intraoperative Factors Associated with Acute Kidney Injury Following Lung Transplant
We examined a number of intraoperative factors, including prolonged hypotension, prolonged acidemia, administration of blood products, and use of intraoperative mechanical support, to determine if these were risk factors for postoperative acute kidney injury (AKI). (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , , S. Miller, E. Sako, N. Das, L. Jones, H. Keyt Source Type: research

Factors Associated with Long-Term Survival in Lung Transplant Recipients Age =70 Years
Purpose: Recipients ≥70 years make up an increasing proportion of total lung transplant recipients but continue to face worse post-transplant outcomes compared to younger recipients. We investigated factors associated with long-term survival in this population. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , B.L. Shou, J.M. Ruck, A.F. Akbar, A. Kalra, A.J. Casillan, J.S. Ha, E.L. Bush, C.A. Merlo Source Type: research

Impact of Perioperative Gabapentinoid Use on Lung Transplant Outcomes
Purpose: In a recent meta-analysis, perioperative gabapentinoid use was associated with greater risk of adverse events in surgical patients. However, it remains unclear how perioperative gabapentinoid use affects lung transplant outcomes. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J.M. Ruck, E.L. Larson, A. Akbar, A.J. Casillan, J.S. Ha, A.B. Massie, D.L. Segev, C.A. Merlo, E.L. Bush Source Type: research

Eighteen-Year Single Center Experience with Lung Transplantation in Pediatric Patients Younger Than 12 Years Old
In this study, we present our 18-year experience with lung transplantation in pediatric patients younger than 12 years old. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: D. Bobylev, J. Carlens, N.D. De Manna, K. Aburahma, C. Mueller, A. Saipbaev, M. Greer, A. Horke, C. Kuehn, M. Avsar, A. Weymann, A. Ruhparwar, N. Schwerk, J. Salman, Source Type: research

Outcome of COVID-19 Positive Donor Lung Transplantation
The objective of this study is to characterize the short-term outcomes of lung transplants from COVID-19-positive donors in the United States. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.T. Kim, P.T. Gaynor, D. Sayah, A. Ardehali Source Type: research

Does Donor-Recipient Age Mismatch Impact the Recipient's Survival in Lung Transplantation?
Purpose: The impact of age mismatch between donors and recipients for lung transplantation has not been clarified. The purpose of this study is to determine the survival outcomes of recipients of aged-mismatched donor lungs. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.T. Kim, Z. Shameem, C.C. Le, S. Lee, A. Ardehali Source Type: research

Lung Transplantation for COVID-19 Lung Failure: Does Bridging with ECMO Impact Outcomes?
Purpose: There has been an increasing number of patients with COVID-19 lung failure requiring ECMO as a bridge to lung transplantation. The purpose of this report is to characterize the outcomes of ECMO as bridge-to-lung transplantation among COVID-19 lung failure patients. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , S.T. Kim, R. Biniwale, D. Sayah, A. Ardehali Source Type: research

Are Highly Sensitized Recipients at Increased Risk for Early or Late Graft Dysfunction After Lung Transplantation?
Purpose: Investigate the association between of pre-transplant higher panel reactive antibody (PRA) and occurrence of high-grade primary graft dysfunction (PGD) after lung transplant (LTx) as well as impact on late outcomes in a contemporary cohort at a high-volume center. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K. Bauza, L. Thuita, W. Tsuang, M. Budev, J. Yun, K. McCurry Source Type: research