Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation - Insights from Castle HTX
The CASTLE-HTx trial demonstrated the benefit of atrial fibrillation (AF) ablation compared to medical therapy in decreasing mortality, need for left ventricular assist device (LVAD) implantation or heart transplantation (HTx) in patients with end-stage heart failure (HF). (Source: Heart Rhythm)
Source: Heart Rhythm - April 9, 2024 Category: Cardiology Authors: Maximilian Moersdorf, Jan G.P. Tijssen, Nassir F. Marrouche, Harry J.G.M. Crijns, Angelika Costard-Jaeckle, Leonard Bergau, Gerhard Hindricks, Nikolaos Dagres, Samuel Sossalla, Rene Schramm, Henrik Fox, Thomas Fink, Mustapha El Hamriti, Vanessa Sciacca, F Source Type: research

Prognosis of patients in end-stage heart failure with atrial fibrillation treated with ablation: Insights from CASTLE-HTx
The CASTLE-HTx trial demonstrated the benefit of atrial fibrillation (AF) ablation compared with medical therapy in decreasing mortality, need for left ventricular assist device implantation, or heart transplantation (HTx) in patients with end-stage heart failure (HF). (Source: Heart Rhythm)
Source: Heart Rhythm - April 9, 2024 Category: Cardiology Authors: Maximilian Moersdorf, Jan G.P. Tijssen, Nassir F. Marrouche, Harry J.G.M. Crijns, Angelika Costard-Jaeckle, Leonard Bergau, Gerhard Hindricks, Nikolaos Dagres, Samuel Sossalla, Rene Schramm, Henrik Fox, Thomas Fink, Mustapha El Hamriti, Vanessa Sciacca, F Source Type: research

Successful prediction of left bundle branch block ‐induced cardiomyopathy and treatment effect by artificial intelligence‐enabled electrocardiogram
ConclusionsArtificial intelligence-enabled ECGS may help identify patients who are at risk of developing LBBB-induced cardiomyopathy and predict the response to LBBA pacing. (Source: Pacing and Clinical Electrophysiology : PACE)
Source: Pacing and Clinical Electrophysiology : PACE - April 8, 2024 Category: Cardiology Authors: Rahul Dhawan, Mohamed Omer, Caitlin Carpenter, Paul A. Friedman, Xiaoke Liu Tags: DEVICES Source Type: research

ABO-incompatible Heart Transplantation - evolution of a revolution
In the 1990s, neonates born with severe congenital heart disease faced more than 50% mortality awaiting an ABO-compatible (ABOc) transplant donor. This desperate situation, together with knowledge on gaps of the adaptive immune system in early childhood, led to the clinical exploration of intentional ABO-incompatible (ABOi) heart transplantation. In 2001, West et al. reported the first series of 10 infants in Canada. Since then, consideration of ABOi heart donors has become standard of care for children awaiting transplantation in the first few years of life, resulting in reduced wait times and better organ utilization wit...
Source: The Journal of Heart and Lung Transplantation - April 8, 2024 Category: Transplant Surgery Authors: Neha Bansal, Lori J. West, Jacob Simmonds, Simon Urschel Tags: State of the art Source Type: research

ABO-incompatible heart transplantation —evolution of a revolution
In the 1990s, neonates born with severe congenital heart disease faced more than 50% mortality awaiting an ABO-compatible (ABOc) transplant donor. This desperate situation, together with knowledge of gaps in the adaptive immune system in early childhood, led to the clinical exploration of intentional ABO-incompatible (ABOi) heart transplantation. In 2001, West et al.  reported the first series of 10 infants in Canada. Since then, consideration of ABOi heart donors has become the standard of care for children awaiting transplantation in the first few years of life, resulting in reduced wait times and better organ utilizati...
Source: The Journal of Heart and Lung Transplantation - April 8, 2024 Category: Transplant Surgery Authors: Neha Bansal, Lori J. West, Jacob Simmonds, Simon Urschel Tags: State of the art Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Recombinant human IL-37 attenuates acute cardiac allograft rejection in mice
CONCLUSIONS: We demonstrated that rhIL-37 effectively suppress acute rejection and induce long-term allograft acceptance. The results highlight that IL-37 could be novel and promising candidate for prevention of allograft rejection.PMID:38583255 | DOI:10.1016/j.cyto.2024.156598 (Source: Cytokine)
Source: Cytokine - April 7, 2024 Category: Molecular Biology Authors: Bo Shao Jing-Yi Zhang Shao-Hua Ren Ya-Fei Qin Hong-da Wang Yong-Chang Gao De-Jun Kong Yong-Hao Hu Hong Qin Guang-Ming Li Hao Wang Source Type: research

Association between pulmonary artery pulsatility and mortality after implantation of left ventricular assist device
ConclusionsPreoperative PAPi  <  2.84 was associated with a higher risk of early mortality after LVAD implantation without impacting 2 year outcomes among survivors. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 6, 2024 Category: Cardiology Authors: Ali Akamkam, Vincent Galand, Marie Jungling, Cl ément Delmas, Camille Dambrin, Mathieu Pernot, Michel Kindo, Philippe Gaudard, Philippe Rouviere, Thomas Senage, Olivier Chavanon, Marylou Para, Vlad Gariboldi, Matteo Pozzi, Pierre‐Yves Lit Tags: Original Article Source Type: research

The Wallet Biopsy: Medical Crowdfunding for Heart Transplantation
In this study, we sought to describe the state of crowdfunding for individuals being evaluated for heart transplantation. Using the search term heart transplant, 1000 GoFundMe campaigns were reviewed. After exclusions, 634 (63.4%) campaigns were included. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - April 6, 2024 Category: Cardiology Authors: ERSILIA M. DEFILIPPIS, ADHYA MEHTA, FATIMAH A. ALKHUNAIZI, CHRISTY N. TAYLOR, JOS É LOPEZ, LAURA MCLAUGHLIN, VANESSA BLUMER, NASRIEN E. IBRAHIM Tags: Brief Report Source Type: research

Balancing Innovation and Professionalism: The Emerging Role of AI-Powered Chatbots in Medical Consultation
The advent of artificial intelligence (AI) in healthcare has opened new frontiers in patient care and medical consultation. Among the most innovative applications of this technology are medical chatbots, which have the potential to revolutionize the way health advice and information are delivered to patients. By leveraging advanced algorithms and vast medical knowledge databases, these chatbots promise to provide immediate, accessible, and personalized medical advice. We explored this ability by using an example from the field of cardiac electrophysiology. (Source: Heart Rhythm)
Source: Heart Rhythm - April 6, 2024 Category: Cardiology Authors: Edward Itelman, Gregory Golovchiner, Alon Barsheshet, Ran Kornowski, Aharon Erez Source Type: research

Partial heart transplantation for destructive infective endocarditis
AbstractInfective endocarditis frequently spreads beyond the valve tissue, especially in the aortic location. Invasive endocarditis may lead to abscess formation or fistula, with substantial tissue loss. Here, the case of a 31-year-old male patient with destructive aortic and pulmonary valve endocarditis and a subaortic mural defect who underwent patch closure of the ventricular septal defect and aortic and pulmonary root replacement and right coronary artery bypass graft is presented. This is an uncommon condition and stress is placed on imaging of the technical aspects of the case. (Source: Indian Journal of Thoracic and...
Source: Indian Journal of Thoracic and Cardiovascular Surgery - April 6, 2024 Category: Cardiovascular & Thoracic Surgery Source Type: research