Human papillomavirus and Epstein-Barr virus infection in benign thyroid lesions
CONCLUSION: The occurrence and development of benign thyroid lesions are closely related to EBV infection. HT combined with thyroid adenoma may be more susceptible to EBV infection than simple HT and thyroid adenoma, which provides a new idea for the diagnosis and treatment of benign thyroid lesions.PMID:38646990 | DOI:10.5603/ep.99339 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yingying Lu Runyu Zhao Yi Zhang Shuixian Huang Xiaoping Chen Source Type: research
Human papillomavirus and Epstein-Barr virus infection in benign thyroid lesions
CONCLUSION: The occurrence and development of benign thyroid lesions are closely related to EBV infection. HT combined with thyroid adenoma may be more susceptible to EBV infection than simple HT and thyroid adenoma, which provides a new idea for the diagnosis and treatment of benign thyroid lesions.PMID:38646990 | DOI:10.5603/ep.99339 (Source: Endokrynologia Polska)
Source: Endokrynologia Polska - April 22, 2024 Category: Endocrinology Authors: Yingying Lu Runyu Zhao Yi Zhang Shuixian Huang Xiaoping Chen Source Type: research
The effect of low-level laser therapy on the oxidative stress level and quality of life in patients with Hashimoto's thyroiditis
This study aimed to examine the effects of low-level laser therapy (LLLT) combined with levothyroxine replacement therapy on thyroid function, oxidative stress (OS), and quality of life in patients with Hashimoto's thyroiditis (HT). Forty-six patients diagnosed with HT were randomized to receive active LLLT (n = 23) and sham LLLT (n = 23) twice a week for three weeks. Clinical and laboratory evaluations of the participants were performed before treatment and three months after treatment. Biochemical parameters were taken from the patient file requested by the physician as a routine examination. Malondialdehyde and nitricox...
Source: Free Radical Research - April 17, 2024 Category: Research Authors: S ümeyye Tunç Şükriye Leyla Altuntaş Murat Atmaca Çağrı Çakıcı T ürkan Yiğitbaşı Yeong-Cheng Liou Wei-An Chang Source Type: research
Targeting the aryl hydrocarbon receptor with FICZ regulates IL-2 and immune infiltration to alleviate Hashimoto's thyroiditis in mice
In conclusion, targeting the AhR with FICZ regulates IL-2 and immune infiltration to alleviate experimental HT, shedding new light on the therapeutic intervention of this prevalent disease.PMID:38621508 | DOI:10.1016/j.ejphar.2024.176588 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - April 15, 2024 Category: Drugs & Pharmacology Authors: Zhengzheng Liao Xianzhong Zeng Xiaoling Guo Qing Shi Ziyun Tang Ping Li Cuiyun Chen Mengxia Chen Jianrong Chen Jixiong Xu Yaojun Cai Source Type: research
Targeting the aryl hydrocarbon receptor with FICZ regulates IL-2 and immune infiltration to alleviate Hashimoto's thyroiditis in mice
In conclusion, targeting the AhR with FICZ regulates IL-2 and immune infiltration to alleviate experimental HT, shedding new light on the therapeutic intervention of this prevalent disease.PMID:38621508 | DOI:10.1016/j.ejphar.2024.176588 (Source: European Journal of Pharmacology)
Source: European Journal of Pharmacology - April 15, 2024 Category: Drugs & Pharmacology Authors: Zhengzheng Liao Xianzhong Zeng Xiaoling Guo Qing Shi Ziyun Tang Ping Li Cuiyun Chen Mengxia Chen Jianrong Chen Jixiong Xu Yaojun Cai Source Type: research
Determination of HLA class II risk alleles and prediction of self/non-self-epitopes contributing Hashimoto's thyroiditis in a group of Iranian patients
This study aimed to determine the HLA-II risk alleles for developing Hashimoto's thyroiditis (HT) in order to analyze the molecular homology between candidate pathogen-derived epitopes and potentially self-antigens (thyroid peroxidase, TPO) based on the presence of HLA risk alleles. HLA-DRB1/-DQB1 genotyping was performed in 100 HT patients and 330 ethnically matched healthy controls to determine the predisposing/protective alleles for HT disease. Then, in silico analysis was conducted to examine the sequence homology between epitopes derived from autoantigens and four potentially relevant pathogens and their binding capac...
Source: Herpes - April 12, 2024 Category: Infectious Diseases Authors: Ata Shirizadeh Shiva Borzouei Zahra Razavi Amir Taherkhani Javad Faradmal Ghasem Solgi Source Type: research
Determination of HLA class II risk alleles and prediction of self/non-self-epitopes contributing Hashimoto's thyroiditis in a group of Iranian patients
This study aimed to determine the HLA-II risk alleles for developing Hashimoto's thyroiditis (HT) in order to analyze the molecular homology between candidate pathogen-derived epitopes and potentially self-antigens (thyroid peroxidase, TPO) based on the presence of HLA risk alleles. HLA-DRB1/-DQB1 genotyping was performed in 100 HT patients and 330 ethnically matched healthy controls to determine the predisposing/protective alleles for HT disease. Then, in silico analysis was conducted to examine the sequence homology between epitopes derived from autoantigens and four potentially relevant pathogens and their binding capac...
Source: Herpes - April 12, 2024 Category: Infectious Diseases Authors: Ata Shirizadeh Shiva Borzouei Zahra Razavi Amir Taherkhani Javad Faradmal Ghasem Solgi Source Type: research
Nomogram to predict central lymph node metastasis in papillary thyroid carcinoma
Clin Exp Metastasis. 2024 Apr 3. doi: 10.1007/s10585-024-10285-3. Online ahead of print.ABSTRACTCentral lymph node metastasis (CLNM) of papillary thyroid carcinoma (PTC) is common. In our study, we built a nomogram to predict CLNM. We retrospectively analyzed 1,392 PTC patients. This group of patients was divided into a training cohort (including 1,009 patients) and a validation cohort (including 383 patients). Analyses of the correlation between inflammatory indicators, ultrasonic characteristics, pathological characteristics and CLNM were conducted. In the training cohort and validation cohort, the metastatic rates of CL...
Source: Cancer Control - April 3, 2024 Category: Cancer & Oncology Authors: Dehui Qiao Xian Deng Ruichen Liang Xu Li Rongjia Zhang Zhi Lei Hui Yang Xiangyu Zhou Source Type: research
A novel electrochemical biosensor based on WO3@AuNPs and HBP@BIBB macromolecular-triggered ATRP for DR1 detection
New J. Chem., 2024, Accepted Manuscript DOI: 10.1039/D4NJ01098A, PaperXiaojing Cui, Yaping Zhang, Hanmeng Zhang, Huai-Xia Yang, Yanju Liu, Fuchun Si The sensitive detection of down-regulator of transcription 1 (DR1) plays an important role in the early diagnosis and treatment of hashimoto's thyroiditis (HT). Herein, we report a novel electrochemical sensor... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - April 2, 2024 Category: Chemistry Authors: Xiaojing Cui Source Type: research
The concentration of interleukin 6 and tumor necrosis factor alpha in saliva and blood of patients with inactive multiple sclerosis and coexisting hashimoto's thyroiditis
Acta Clin Croat. 2023 Aug;62(2):339-344. doi: 10.20471/acc.2023.62.02.12.ABSTRACTThe concentration of interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) in the blood is higher in patients with active multiple sclerosis (MS) compared to those with inactive disease. The concentration of IL-6 and TNF-α in the blood is higher in patients with Hashimoto's thyroiditis (HT) compared to those with a healthy thyroid. The aim of the study was to assess whether serum IL-6 and TNF-α levels correlated with saliva in patients with inactive MS and whether there was a difference in these groups of patients depending of thyroi...
Source: Acta Clinica Croatica - March 29, 2024 Category: General Medicine Authors: Ines Šiško Markoš Maja Franceschi Valentina Vidranski Pave Marko š Tomislav Juki ć Ana Fr öbe Vanja Ba šić Kes Source Type: research
