Hypothyroidism in older adults: A narrative review
CONCLUSION: Defining optimal diagnostic approaches and targeted therapeutic strategies should be considered in the personalized management of aged patients with hypothyroidism.PMID:37641994 | DOI:10.2174/1871530323666230828110153 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 29, 2023 Category: Drugs & Pharmacology Authors: Vincenzo Fiore Alessandra Barucca S Barraco Domenico Triggiani Giovanni Carbotta Vito Angelo Giagulli Giuseppina Piazzolla Giuseppe Lisco Vincenzo Triggiani Source Type: research

Hypothyroidism in older adults: A narrative review
CONCLUSION: Defining optimal diagnostic approaches and targeted therapeutic strategies should be considered in the personalized management of aged patients with hypothyroidism.PMID:37641994 | DOI:10.2174/1871530323666230828110153 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 29, 2023 Category: Endocrinology Authors: Vincenzo Fiore Alessandra Barucca S Barraco Domenico Triggiani Giovanni Carbotta Vito Angelo Giagulli Giuseppina Piazzolla Giuseppe Lisco Vincenzo Triggiani Source Type: research

Hypothyroidism in older adults: A narrative review
CONCLUSION: Defining optimal diagnostic approaches and targeted therapeutic strategies should be considered in the personalized management of aged patients with hypothyroidism.PMID:37641994 | DOI:10.2174/1871530323666230828110153 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 29, 2023 Category: Drugs & Pharmacology Authors: Vincenzo Fiore Alessandra Barucca S Barraco Domenico Triggiani Giovanni Carbotta Vito Angelo Giagulli Giuseppina Piazzolla Giuseppe Lisco Vincenzo Triggiani Source Type: research

Hypothyroidism in older adults: A narrative review
CONCLUSION: Defining optimal diagnostic approaches and targeted therapeutic strategies should be considered in the personalized management of aged patients with hypothyroidism.PMID:37641994 | DOI:10.2174/1871530323666230828110153 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 29, 2023 Category: Endocrinology Authors: Vincenzo Fiore Alessandra Barucca S Barraco Domenico Triggiani Giovanni Carbotta Vito Angelo Giagulli Giuseppina Piazzolla Giuseppe Lisco Vincenzo Triggiani Source Type: research

Hypothyroidism in older adults: A narrative review
CONCLUSION: Defining optimal diagnostic approaches and targeted therapeutic strategies should be considered in the personalized management of aged patients with hypothyroidism.PMID:37641994 | DOI:10.2174/1871530323666230828110153 (Source: Endocrine, Metabolic and Immune Disorders Drug Targets)
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - August 29, 2023 Category: Drugs & Pharmacology Authors: Vincenzo Fiore Alessandra Barucca S Barraco Domenico Triggiani Giovanni Carbotta Vito Angelo Giagulli Giuseppina Piazzolla Giuseppe Lisco Vincenzo Triggiani Source Type: research

A case of Marine Lenhart syndrome with Hashimoto ’s thyroiditis that mimicked thyroid carcinoma
Marine Lenhart syndrome is a rare disease and causes refractory hyperthyroidism. So far, little evidence on the combination of both Marine Lenhart syndrome and Hashimoto's thyroiditis is available. We suspect ... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - August 28, 2023 Category: Endocrinology Authors: Peng Ye, Lan Li, Dong Wei, Fan Li, Yuan Zhong and Jing Zeng Tags: Case report Source Type: research

Th1 or Th2 cytokines are correlated with Tregs and T cell subsets and pregnancy outcomes in patients with autoimmune thyroid disease during early, middle, late pregnancy, and postpartum period
Hum Immunol. 2023 Aug 8:S0198-8859(23)00111-8. doi: 10.1016/j.humimm.2023.07.002. Online ahead of print.ABSTRACTAutoimmune thyroid disease (AITD) is a T lymphocytes-mediated autoimmune disorder affecting pregnant women. The current study sought to determine the correlations between T helper-1 (Th1)/T helper-2 (Th2) cytokines and regulatory T cells (Tregs) and T cell subsets and pregnancy outcomes in AITD patients during early pregnancy (T1), middle pregnancy (T2), late pregnancy (T3), and postpartum period (PP). A total of 60 patients with Graves' disease, 60 patients with Hashimoto's thyroiditis, and 30 healthy pregnant w...
Source: Human Immunology - August 10, 2023 Category: Allergy & Immunology Authors: Mei Zhong Hui Chen Jiao Lan Chunyong Lan Lan Liang Jingming Yu Hua Zhong Xing Zhou Jie Lu Xiaoyan Tan Wensheng Lu Source Type: research

Th1 or Th2 cytokines are correlated with Tregs and T cell subsets and pregnancy outcomes in patients with autoimmune thyroid disease during early, middle, late pregnancy, and postpartum period
Hum Immunol. 2023 Aug 8:S0198-8859(23)00111-8. doi: 10.1016/j.humimm.2023.07.002. Online ahead of print.ABSTRACTAutoimmune thyroid disease (AITD) is a T lymphocytes-mediated autoimmune disorder affecting pregnant women. The current study sought to determine the correlations between T helper-1 (Th1)/T helper-2 (Th2) cytokines and regulatory T cells (Tregs) and T cell subsets and pregnancy outcomes in AITD patients during early pregnancy (T1), middle pregnancy (T2), late pregnancy (T3), and postpartum period (PP). A total of 60 patients with Graves' disease, 60 patients with Hashimoto's thyroiditis, and 30 healthy pregnant w...
Source: Human Immunology - August 10, 2023 Category: Allergy & Immunology Authors: Mei Zhong Hui Chen Jiao Lan Chunyong Lan Lan Liang Jingming Yu Hua Zhong Xing Zhou Jie Lu Xiaoyan Tan Wensheng Lu Source Type: research

Th1 or Th2 cytokines are correlated with Tregs and T cell subsets and pregnancy outcomes in patients with autoimmune thyroid disease during early, middle, late pregnancy, and postpartum period
Hum Immunol. 2023 Aug 8:S0198-8859(23)00111-8. doi: 10.1016/j.humimm.2023.07.002. Online ahead of print.ABSTRACTAutoimmune thyroid disease (AITD) is a T lymphocytes-mediated autoimmune disorder affecting pregnant women. The current study sought to determine the correlations between T helper-1 (Th1)/T helper-2 (Th2) cytokines and regulatory T cells (Tregs) and T cell subsets and pregnancy outcomes in AITD patients during early pregnancy (T1), middle pregnancy (T2), late pregnancy (T3), and postpartum period (PP). A total of 60 patients with Graves' disease, 60 patients with Hashimoto's thyroiditis, and 30 healthy pregnant w...
Source: Human Immunology - August 10, 2023 Category: Allergy & Immunology Authors: Mei Zhong Hui Chen Jiao Lan Chunyong Lan Lan Liang Jingming Yu Hua Zhong Xing Zhou Jie Lu Xiaoyan Tan Wensheng Lu Source Type: research

Th1 or Th2 cytokines are correlated with Tregs and T cell subsets and pregnancy outcomes in patients with autoimmune thyroid disease during early, middle, late pregnancy, and postpartum period
Hum Immunol. 2023 Aug 8:S0198-8859(23)00111-8. doi: 10.1016/j.humimm.2023.07.002. Online ahead of print.ABSTRACTAutoimmune thyroid disease (AITD) is a T lymphocytes-mediated autoimmune disorder affecting pregnant women. The current study sought to determine the correlations between T helper-1 (Th1)/T helper-2 (Th2) cytokines and regulatory T cells (Tregs) and T cell subsets and pregnancy outcomes in AITD patients during early pregnancy (T1), middle pregnancy (T2), late pregnancy (T3), and postpartum period (PP). A total of 60 patients with Graves' disease, 60 patients with Hashimoto's thyroiditis, and 30 healthy pregnant w...
Source: Human Immunology - August 10, 2023 Category: Allergy & Immunology Authors: Mei Zhong Hui Chen Jiao Lan Chunyong Lan Lan Liang Jingming Yu Hua Zhong Xing Zhou Jie Lu Xiaoyan Tan Wensheng Lu Source Type: research

Comprehensive analysis of hub biomarkers associated with immune and oxidative stress in Hashimoto's thyroiditis
Arch Biochem Biophys. 2023 Aug 3:109713. doi: 10.1016/j.abb.2023.109713. Online ahead of print.ABSTRACTHashimoto's thyroiditis (HT) is a type of autoimmune disorder with a complex interplay between immune disorder and oxidative stress (OS). This research aimed to discover biomarkers and potential treatment targets associated with immune and OS dysregulation in HT through integrated bioinformatics analysis and clinical validations. Differential gene expression analysis of GSE138198 dataset from the GEO database identified 1490 differentially expressed genes (DEGs) in HT, including 883 upregulated and 607 downregulated genes...
Source: Archives of Biochemistry and Biophysics - August 5, 2023 Category: Biochemistry Authors: Bojin Xu Shan Huang Wenfang Peng Guanjun Cai Haiping Zhou Yiming Guo Juan Du Xiaoxu Ge Xiaohong Wu Source Type: research

Comprehensive analysis of hub biomarkers associated with immune and oxidative stress in Hashimoto's thyroiditis
Arch Biochem Biophys. 2023 Aug 3:109713. doi: 10.1016/j.abb.2023.109713. Online ahead of print.ABSTRACTHashimoto's thyroiditis (HT) is a type of autoimmune disorder with a complex interplay between immune disorder and oxidative stress (OS). This research aimed to discover biomarkers and potential treatment targets associated with immune and OS dysregulation in HT through integrated bioinformatics analysis and clinical validations. Differential gene expression analysis of GSE138198 dataset from the GEO database identified 1490 differentially expressed genes (DEGs) in HT, including 883 upregulated and 607 downregulated genes...
Source: Archives of Biochemistry and Biophysics - August 5, 2023 Category: Biochemistry Authors: Bojin Xu Shan Huang Wenfang Peng Guanjun Cai Haiping Zhou Yiming Guo Juan Du Xiaoxu Ge Xiaohong Wu Source Type: research

Comprehensive analysis of hub biomarkers associated with immune and oxidative stress in Hashimoto's thyroiditis
Arch Biochem Biophys. 2023 Aug 3:109713. doi: 10.1016/j.abb.2023.109713. Online ahead of print.ABSTRACTHashimoto's thyroiditis (HT) is a type of autoimmune disorder with a complex interplay between immune disorder and oxidative stress (OS). This research aimed to discover biomarkers and potential treatment targets associated with immune and OS dysregulation in HT through integrated bioinformatics analysis and clinical validations. Differential gene expression analysis of GSE138198 dataset from the GEO database identified 1490 differentially expressed genes (DEGs) in HT, including 883 upregulated and 607 downregulated genes...
Source: Archives of Biochemistry and Biophysics - August 5, 2023 Category: Biochemistry Authors: Bojin Xu Shan Huang Wenfang Peng Guanjun Cai Haiping Zhou Yiming Guo Juan Du Xiaoxu Ge Xiaohong Wu Source Type: research

Patients with Hashimoto's thyroiditis present higher immune response to COVID-19  mRNA vaccine compared to normal individuals
CONCLUSIONS: Patients with Hashimoto's thyroiditis show significantly higher immune response after the third dose of the COVID-19 mRNA vaccine compared with normal individuals. Obese patients with Hashimoto's thyroiditis show additionally a significantly higher immune response compared with lean patients.PMID:37515710 | DOI:10.1007/s42000-023-00470-6 (Source: Hormones)
Source: Hormones - July 29, 2023 Category: Endocrinology Authors: Antonis Polymeris Petros D Papapetrou Stavroula Psachna Dimitrios Ioannidis Dimitrios Lilis Maria Drakou Aristeidis Vaiopoulos Vaia Polymerou Georgios Spanos Source Type: research