Metabolites from specific intestinal bacteria in vivo fermenting Lycium barbarum polysaccharide improve collagenous arthritis in rats
Int J Biol Macromol. 2022 Nov 25:S0141-8130(22)02815-X. doi: 10.1016/j.ijbiomac.2022.11.257. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is an autoimmune disease affected patients' quality of life severely. Our previous study found Lycium barbarum polysaccharide (LBP) alleviated RA, but it remains unknown whether gut microbiota is necessary for the alleviation. Here, RA models were established in rats with microbiota and rats treated by antibiotic cocktail, and LBP was applied for the intervention on rats. The biochemical test, 16S rDNA sequencing and metabolome analysis were applied to analyze the effects of L...
Source: International Journal of Biological Macromolecules - November 28, 2022 Category: Biochemistry Authors: Yanghanxiu Liu Liu Liu Jianming Luo Xichun Peng Source Type: research
Metabolites from specific intestinal bacteria in vivo fermenting Lycium barbarum polysaccharide improve collagenous arthritis in rats
Int J Biol Macromol. 2022 Nov 25:S0141-8130(22)02815-X. doi: 10.1016/j.ijbiomac.2022.11.257. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is an autoimmune disease affected patients' quality of life severely. Our previous study found Lycium barbarum polysaccharide (LBP) alleviated RA, but it remains unknown whether gut microbiota is necessary for the alleviation. Here, RA models were established in rats with microbiota and rats treated by antibiotic cocktail, and LBP was applied for the intervention on rats. The biochemical test, 16S rDNA sequencing and metabolome analysis were applied to analyze the effects of L...
Source: International Journal of Biological Macromolecules - November 28, 2022 Category: Biochemistry Authors: Yanghanxiu Liu Liu Liu Jianming Luo Xichun Peng Source Type: research
Lycium Barbarum polysaccharides ameliorates hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting blood-brain barrier
CONCLUSIONS: These results demonstrated that LBP could ameliorate hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting the blood-brain barrier.PMID:36436794 | DOI:10.1016/j.trim.2022.101757 (Source: Transplant Immunology)
Source: Transplant Immunology - November 27, 2022 Category: Transplant Surgery Authors: Qi Zhao Yu-Meng Jing Mao-Tao He Li Jing Yan-Feng Xi Jian-Zhong Zhang Source Type: research
Lycium Barbarum polysaccharides ameliorates hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting blood-brain barrier
CONCLUSIONS: These results demonstrated that LBP could ameliorate hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting the blood-brain barrier.PMID:36436794 | DOI:10.1016/j.trim.2022.101757 (Source: Transplant Immunology)
Source: Transplant Immunology - November 27, 2022 Category: Transplant Surgery Authors: Qi Zhao Yu-Meng Jing Mao-Tao He Li Jing Yan-Feng Xi Jian-Zhong Zhang Source Type: research
Lycium Barbarum polysaccharides ameliorates hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting blood-brain barrier
CONCLUSIONS: These results demonstrated that LBP could ameliorate hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting the blood-brain barrier.PMID:36436794 | DOI:10.1016/j.trim.2022.101757 (Source: Transplant Immunology)
Source: Transplant Immunology - November 27, 2022 Category: Transplant Surgery Authors: Qi Zhao Yu-Meng Jing Mao-Tao He Li Jing Yan-Feng Xi Jian-Zhong Zhang Source Type: research
Lycium Barbarum polysaccharides ameliorates hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting blood-brain barrier
Transpl Immunol. 2022 Nov 24;76:101757. doi: 10.1016/j.trim.2022.101757. Online ahead of print.NO ABSTRACTPMID:36436794 | DOI:10.1016/j.trim.2022.101757 (Source: Transplant Immunology)
Source: Transplant Immunology - November 27, 2022 Category: Transplant Surgery Authors: Qi Zhao Yu-Meng Jing Mao-Tao He Li Jing Yan-Feng Xi Jian-Zhong Zhang Source Type: research
Lycium Barbarum polysaccharides ameliorates hyperglycemia-exacerbated cerebral ischemia/reperfusion injury via protecting blood-brain barrier
Transpl Immunol. 2022 Nov 24;76:101757. doi: 10.1016/j.trim.2022.101757. Online ahead of print.NO ABSTRACTPMID:36436794 | DOI:10.1016/j.trim.2022.101757 (Source: Transplant Immunology)
Source: Transplant Immunology - November 27, 2022 Category: Transplant Surgery Authors: Qi Zhao Yu-Meng Jing Mao-Tao He Li Jing Yan-Feng Xi Jian-Zhong Zhang Source Type: research
Corrigendum: Lycium barbarum Glycopeptide prevents the development and progression of acute colitis by regulating the composition and diversity of the gut microbiota in mice
(Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - November 17, 2022 Category: Microbiology Source Type: research
Potential cerebrovascular protective functions of lycium barbarum polysaccharide in alleviating hyperglycemia-aggravated cerebral ischemia/reperfusion injury in hyperglycemic rats
CONCLUSIONS: The intake of LBP benefits the cerebrovascular structure and vasoreactivity in diabetic rats. Our research provides a possible new strategy for treating stroke in patients with DM.PMID:36314308 | DOI:10.26355/eurrev_202210_30007 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - October 31, 2022 Category: Drugs & Pharmacology Authors: H-F Jiang Y-Q Guo F U Rehman L Jing J-Z Zhang Source Type: research
Potential cerebrovascular protective functions of lycium barbarum polysaccharide in alleviating hyperglycemia-aggravated cerebral ischemia/reperfusion injury in hyperglycemic rats
CONCLUSIONS: The intake of LBP benefits the cerebrovascular structure and vasoreactivity in diabetic rats. Our research provides a possible new strategy for treating stroke in patients with DM.PMID:36314308 | DOI:10.26355/eurrev_202210_30007 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - October 31, 2022 Category: Drugs & Pharmacology Authors: H-F Jiang Y-Q Guo F U Rehman L Jing J-Z Zhang Source Type: research
Effects of Lycium Barbarum Polysaccharides on the Metabolism of Dendritic Cells: An < em > In Vitro < /em > Study
This study is aimed at exploring the mechanism of LBP affecting DCs function from the perspective of metabolomics. MTT method was used to detect the activity of DC2.4 cells. ELISA kit method was used to detect the contents of IL-6, IL-12, and TNF-α in the supernatant of cells. Ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF/MS) was used to detect general changes in DC2.4 cell metabolism. And then multidistance covariates and bioinformatics, partial least squares-discriminant analysis (PLS-DA) were used to analyze differential metabolites. Finally, metabolic pathway analysis ...
Source: Journal of Immunology Research - October 31, 2022 Category: Allergy & Immunology Authors: Baochen Zhang Kengyu Chen Li Liu Xiuyun Li Enhui Wu Liang Han Zhongfeng Shi Xiangliang Deng Source Type: research
Effects of Lycium Barbarum Polysaccharides on the Metabolism of Dendritic Cells: An < em > In Vitro < /em > Study
This study is aimed at exploring the mechanism of LBP affecting DCs function from the perspective of metabolomics. MTT method was used to detect the activity of DC2.4 cells. ELISA kit method was used to detect the contents of IL-6, IL-12, and TNF-α in the supernatant of cells. Ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF/MS) was used to detect general changes in DC2.4 cell metabolism. And then multidistance covariates and bioinformatics, partial least squares-discriminant analysis (PLS-DA) were used to analyze differential metabolites. Finally, metabolic pathway analysis ...
Source: Cell Research - October 31, 2022 Category: Cytology Authors: Baochen Zhang Kengyu Chen Li Liu Xiuyun Li Enhui Wu Liang Han Zhongfeng Shi Xiangliang Deng Source Type: research
Potential cerebrovascular protective functions of lycium barbarum polysaccharide in alleviating hyperglycemia-aggravated cerebral ischemia/reperfusion injury in hyperglycemic rats
CONCLUSIONS: The intake of LBP benefits the cerebrovascular structure and vasoreactivity in diabetic rats. Our research provides a possible new strategy for treating stroke in patients with DM.PMID:36314308 | DOI:10.26355/eurrev_202210_30007 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - October 31, 2022 Category: Drugs & Pharmacology Authors: H-F Jiang Y-Q Guo F U Rehman L Jing J-Z Zhang Source Type: research
Potential cerebrovascular protective functions of lycium barbarum polysaccharide in alleviating hyperglycemia-aggravated cerebral ischemia/reperfusion injury in hyperglycemic rats
CONCLUSIONS: The intake of LBP benefits the cerebrovascular structure and vasoreactivity in diabetic rats. Our research provides a possible new strategy for treating stroke in patients with DM.PMID:36314308 | DOI:10.26355/eurrev_202210_30007 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - October 31, 2022 Category: Drugs & Pharmacology Authors: H-F Jiang Y-Q Guo F U Rehman L Jing J-Z Zhang Source Type: research
Effects of Lycium Barbarum Polysaccharides on the Metabolism of Dendritic Cells: An < em > In Vitro < /em > Study
This study is aimed at exploring the mechanism of LBP affecting DCs function from the perspective of metabolomics. MTT method was used to detect the activity of DC2.4 cells. ELISA kit method was used to detect the contents of IL-6, IL-12, and TNF-α in the supernatant of cells. Ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-Q-TOF/MS) was used to detect general changes in DC2.4 cell metabolism. And then multidistance covariates and bioinformatics, partial least squares-discriminant analysis (PLS-DA) were used to analyze differential metabolites. Finally, metabolic pathway analysis ...
Source: Journal of Immunology Research - October 31, 2022 Category: Allergy & Immunology Authors: Baochen Zhang Kengyu Chen Li Liu Xiuyun Li Enhui Wu Liang Han Zhongfeng Shi Xiangliang Deng Source Type: research
