Neuroprotective effects of goji berry (Lycium barbarum L.) polysaccharides on depression-like behavior in ovariectomized rats: behavioral and biochemical evidence
CONCLUSION: This is the first study to show the antidepressant effect of LBP. Although additional research is needed, LBP may be considered a potential new antidepressant.PMID:37654035 | PMC:PMC10509687 | DOI:10.3325/cmj.2023.64.231 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 1, 2023 Category: General Medicine Authors: Hayriye Soyt ürk Bihter G ökçe Bozat Fatma Pehlivan Karakas Hamit Coskun Tulin Firat Source Type: research
Neuroprotective effects of goji berry (Lycium barbarum L.) polysaccharides on depression-like behavior in ovariectomized rats: behavioral and biochemical evidence
CONCLUSION: This is the first study to show the antidepressant effect of LBP. Although additional research is needed, LBP may be considered a potential new antidepressant.PMID:37654035 | PMC:PMC10509687 | DOI:10.3325/cmj.2023.64.231 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 1, 2023 Category: General Medicine Authors: Hayriye Soyt ürk Bihter G ökçe Bozat Fatma Pehlivan Karakas Hamit Coskun Tulin Firat Source Type: research
Neuroprotective effects of goji berry (Lycium barbarum L.) polysaccharides on depression-like behavior in ovariectomized rats: behavioral and biochemical evidence
CONCLUSION: This is the first study to show the antidepressant effect of LBP. Although additional research is needed, LBP may be considered a potential new antidepressant.PMID:37654035 | PMC:PMC10509687 | DOI:10.3325/cmj.2023.64.231 (Source: Croatian Medical Journal)
Source: Croatian Medical Journal - September 1, 2023 Category: General Medicine Authors: Hayriye Soyt ürk Bihter G ökçe Bozat Fatma Pehlivan Karakas Hamit Coskun Tulin Firat Source Type: research
The mechanism of Qijing Mingmu decoction on cellular senescence of conjunctivochalasis
Qijing Mingmu decoction (QJMM), a compound Chinese medicine preparation, which consists of Lycium barbarum, Polygonatum, Ophiopogon japonicus, Poria cocos, Glycyrrhiza, Eclipta prostrata and Ligusticum striatu... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - August 29, 2023 Category: Complementary Medicine Authors: Minhong Xiang, Jiang Liu, Kai Ma, Yongyi Sha, Yueping Zhan, Wei Zhang and Xueqing Kong Tags: Research article Source Type: research
Development and characterization of a new potato starch/watermelon peel pectin composite film loaded with TiO < sub > 2 < /sub > nanoparticles and microencapsulated Lycium barbarum leaf flavonoids and its use in the Tan mutton packaging
Int J Biol Macromol. 2023 Aug 25:126532. doi: 10.1016/j.ijbiomac.2023.126532. Online ahead of print.ABSTRACTReinforced edible film with active nanoparticles has been in increasing demand as a new technology to improve the quality and extend the shelf-life of muscle foods. The study aimed to fabricate and characterize a novel potato starch (Pst)/watermelon peel pectin (Wpp) composite film with the microencapsulated Lycium barbarum leaf flavonoids (MLF) and nano-TiO2 (Pst/Wpp/MLF/TiO2) and further apply the film in Tan mutton preservation. The moisture content, thickness and water vapor permeability (WVP) of the composite fi...
Source: International Journal of Biological Macromolecules - August 27, 2023 Category: Biochemistry Authors: Qiwen Xie Xuexia Liu Yuanlv Zhang Guishan Liu Source Type: research
Preclinical pharmacokinetics-related pharmacological effects of orally administered polysaccharides from traditional Chinese medicines: A review
This article aims to review the literature published mainly from 2010 to 2022, focusing on the relationship between pharmacokinetics and pharmacological effects. It has been found that unabsorbed TCMPs can exert local pharmacological effects in the gut, including anti-inflammation, anti-oxidation, regulation of intestinal flora, modulation of intestinal immunity, and maintenance of intestinal barrier integrity. Unabsorbed TCMPs can also produce systemic pharmacological effects, such as anti-tumor activity and immune system modulation, by regulating intestinal flora and immunity. Conversely, some TCMPs can be absorbed and d...
Source: International Journal of Biological Macromolecules - August 25, 2023 Category: Biochemistry Authors: Dan Ye Qing Zhao Ding Ding Bing-Liang Ma Source Type: research
Preclinical pharmacokinetics-related pharmacological effects of orally administered polysaccharides from traditional Chinese medicines: A review
This article aims to review the literature published mainly from 2010 to 2022, focusing on the relationship between pharmacokinetics and pharmacological effects. It has been found that unabsorbed TCMPs can exert local pharmacological effects in the gut, including anti-inflammation, anti-oxidation, regulation of intestinal flora, modulation of intestinal immunity, and maintenance of intestinal barrier integrity. Unabsorbed TCMPs can also produce systemic pharmacological effects, such as anti-tumor activity and immune system modulation, by regulating intestinal flora and immunity. Conversely, some TCMPs can be absorbed and d...
Source: International Journal of Biological Macromolecules - August 25, 2023 Category: Biochemistry Authors: Dan Ye Qing Zhao Ding Ding Bing-Liang Ma Source Type: research
Neuroprotective effects of Lycium barbarum polysaccharide on light-induced oxidative stress and mitochondrial damage via the Nrf2/HO-1 pathway in mouse hippocampal neurons
Int J Biol Macromol. 2023 Aug 13:126315. doi: 10.1016/j.ijbiomac.2023.126315. Online ahead of print.ABSTRACTLight at night (LAN) induced cognitive impairment associated with oxidative stress in mice has been reported. Lycium barbarum polysaccharide (LBP) exhibits anti-tumor, anti-oxidant and neuroprotective effects, yet the neuroprotective effect on light-induced neuron damage still unclear. Here, mice exposed to LAN displayed cognitive impairment and depressive like behavior, which was reversed by LBP treatment. Meanwhile, LBP alleviated light-induced higher apoptosis and mitochondrial damage in HT-22 cells. Also, LBP pre...
Source: International Journal of Biological Macromolecules - August 15, 2023 Category: Biochemistry Authors: Yang Yang Lin Yu Tianyu Zhu Shuwen Xu Jin He Ningning Mao Zhenguang Liu Deyun Wang Source Type: research
Neuroprotective effects of Lycium barbarum polysaccharide on light-induced oxidative stress and mitochondrial damage via the Nrf2/HO-1 pathway in mouse hippocampal neurons
Int J Biol Macromol. 2023 Aug 13:126315. doi: 10.1016/j.ijbiomac.2023.126315. Online ahead of print.ABSTRACTLight at night (LAN) induced cognitive impairment associated with oxidative stress in mice has been reported. Lycium barbarum polysaccharide (LBP) exhibits anti-tumor, anti-oxidant and neuroprotective effects, yet the neuroprotective effect on light-induced neuron damage still unclear. Here, mice exposed to LAN displayed cognitive impairment and depressive like behavior, which was reversed by LBP treatment. Meanwhile, LBP alleviated light-induced higher apoptosis and mitochondrial damage in HT-22 cells. Also, LBP pre...
Source: International Journal of Biological Macromolecules - August 15, 2023 Category: Biochemistry Authors: Yang Yang Lin Yu Tianyu Zhu Shuwen Xu Jin He Ningning Mao Zhenguang Liu Deyun Wang Source Type: research
Potential role of < em > Lycium barbarum < /em > polysaccharides in glaucoma management: evidence from preclinical < em > in vivo < /em > studies
Neural Regen Res. 2023 Dec;18(12):2623-2632. doi: 10.4103/1673-5374.355977.ABSTRACTIn recent years, the pharmacological benefits of herbal extracts have been revisited for their potential neuroprotective effects in glaucoma. The polysaccharides extracted from the fruits of Lycium barbarum L., or Lycium barbarum polysaccharides, exert their anti-aging effect through reducing oxidative stress, modulating the immune response, enhancing neuronal responses, and promoting cytoprotection. The therapeutic efficacy of Lycium barbarum polysaccharides in preserving retinal ganglion cells and their functions was demonstrated in a rang...
Source: Cell Research - July 14, 2023 Category: Cytology Authors: Yamunadevi Lakshmanan Francisca Siu Yin Wong Kwok-Fai So Henry Ho-Lung Chan Source Type: research
Slit dual-frequency ultrasound-assisted pulping of Lycium barbarum fresh fruit to improve the dissolution of polysaccharides and in situ real-time monitoring
In this study, the slit dual-frequency ultrasound-assisted pulping of fresh Lycium barbarum fruit was optimized to improve the dissolution of polysaccharides. The microscopic mechanism of polysaccharide dissolution was explored through establishing polysaccharides dissolution kinetics model and visualizing the multi-physical fields during ultrasonic process, and an in situ real-time monitoring model was established by the relationship between the chemical value and spectral information collected by near-infrared spectroscopy. The results showed that, under optimal conditions, treatment with ultrasound (28-33 kHz, 250 W, 30...
Source: Ultrasonics Sonochemistry - July 5, 2023 Category: Chemistry Authors: Tianyu Kong Shuhan Liu Yuqin Feng Yanli Fan Junwei Yu Haihui Zhang Meihong Cai Haile Ma Yuqing Duan Source Type: research
Combination of Lycium barbarum L. and Laminaria japonica polysaccharides as a highly efficient prebiotic: Optimal screening and complementary regulation of gut probiotics and their metabolites
This study aimed to optimally select a combination of Lycium barbarum L. polysaccharide (LBP) and Laminaria japonica polysaccharide (LJP) as a highly efficient prebiotic to regulate the gut probiotics and their metabolites. Two LBPs characterized as rhamnogalacturonan I enriched pectins and two LJPs characterized as fucoidans were obtained by enzyme-assisted acid extraction at moderate and dramatic temperatures and combined in pairs to obtain 4 groups containing 4 proportional combinations. All combinations showed better prebiotic effects than individual LJP. The combination of LBP and LJP extracted at 50 °C at a ratio of...
Source: International Journal of Biological Macromolecules - June 24, 2023 Category: Biochemistry Authors: Qianni Chen Jiaqi Fan Lianzhu Lin Mouming Zhao Source Type: research
Combination of Lycium barbarum L. and Laminaria japonica polysaccharides as a highly efficient prebiotic: Optimal screening and complementary regulation of gut probiotics and their metabolites
This study aimed to optimally select a combination of Lycium barbarum L. polysaccharide (LBP) and Laminaria japonica polysaccharide (LJP) as a highly efficient prebiotic to regulate the gut probiotics and their metabolites. Two LBPs characterized as rhamnogalacturonan I enriched pectins and two LJPs characterized as fucoidans were obtained by enzyme-assisted acid extraction at moderate and dramatic temperatures and combined in pairs to obtain 4 groups containing 4 proportional combinations. All combinations showed better prebiotic effects than individual LJP. The combination of LBP and LJP extracted at 50 °C at a ratio of...
Source: International Journal of Biological Macromolecules - June 24, 2023 Category: Biochemistry Authors: Qianni Chen Jiaqi Fan Lianzhu Lin Mouming Zhao Source Type: research
Molecules, Vol. 28, Pages 4930: Comparative Analysis of Polyphenols in Lycium barbarum Fruits Using UPLC-IM-QTOF-MS
This study provided scientific guidance for comprehensive applications of polyphenols from different varieties of L. barbarum from separate geographical origins. (Source: Molecules)
Source: Molecules - June 22, 2023 Category: Chemistry Authors: Yanjun Ju Yujie Wang Lei Ma Lu Kang Hejiang Liu Xue Ma Duoyong Zhao Tags: Article Source Type: research
Lycium barbarum polysaccharides improve lipid metabolism disorders of spotted sea bass Lateolabrax maculatus induced by high lipid diet
Int J Biol Macromol. 2023 May 30:125122. doi: 10.1016/j.ijbiomac.2023.125122. Online ahead of print.ABSTRACTThis experiment explored the effects of Lycium barbarum polysaccharides (LBP) on lipid metabolism of spotted sea bass Lateolabrax maculatus. Blank and experimental control diets with 100 and 150 g/kg lipid were designed, respectively, and three dosages of LBP (0.75, 1.00, 1.25 g/kg) were supplemented in the experimental control diet. A total 375 of spotted sea bass (19.33 ± 0.15) g were divided into 5 groups, and were given experimental diets for 56 days, respectively. Results showed fish were induced to lipid metab...
Source: International Journal of Biological Macromolecules - June 1, 2023 Category: Biochemistry Authors: Zhangfan Huang Youling Ye Zhongying Long Huihui Qin Longhui Liu Anle Xu Zhongbao Li Source Type: research
