Fight Aging! Newsletter, April 15th 2019
In this study, we found that senescent chondrocytes isolated from OA patients secrete more EVs compared with nonsenescent chondrocytes. These EVs inhibit cartilage ECM deposition by healthy chondrocytes and can induce a senescent state in nearby cells. We profiled the miR and protein content of EVs isolated from the synovial fluid of OA joints from mice with SnCs. After treatment with a molecule to remove SnCs, termed a senolytic, the composition of EV-associated miR and protein was markedly altered. The senolytic reduced OA development and enhanced chondrogenesis, and these were attributable to several specific differenti...
Source: Fight Aging! - April 14, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Calorie Restriction Reduces Inflammation via Moderate Hyperadrenocorticism
The metabolic response to calorie restriction, a sustained reduction in calorie intake while maintaining optimal micronutrient intake, is sweeping and complex. It also extends life span quite dramatically in short-lived species. Near everything changes, which makes it a challenge to characterize the few important mechanisms early in the chain of cause and effect. It also makes it a very fruitful area of study from the pure science perspective, as there is always something new to be discovered, as illustrated by the research results reported here. While calorie restriction itself is widely studied, and a good lifesty...
Source: Fight Aging! - April 11, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Medicare: Ripe for Rip-Offs
The $768 billion Medicare program is in deep trouble as America ages and elderly health care soars in cost. Medicare is a giant central planning scheme that imposes more than 100,000 pages of regulations and related rules on more than 600,000 health care providers.   The inefficiency is vast, and the structure of the program makes it a perfect target for fraud and abuse. The system processes more than a billion provider claims a year. Auditorsestimate that more than $50 billion of taxpayer money goes down the drain every year from improper payments. TheNew York Timeshighlights some alleged scams today stemming from a rec...
Source: Cato-at-liberty - April 10, 2019 Category: American Health Authors: Chris Edwards Source Type: blogs

CBD Oil for Depression, Schizophrenia, ADHD, PTSD, Anxiety, Bipolar & More
In conclusion, the studies presented in the current review demonstrate that CBD has the potential to limit delta-9-THC-induced cognitive impairment and improve cognitive function in various pathological conditions. Human studies suggest that CBD may have a protective role in delta-9-THC-induced cognitive impairments; however, there is limited human evidence for CBD treatment effects in pathological states (e.g. schizophrenia). In short, they found that CBD may help alleviate the negative impact of a person with schizophrenia from taking cannabis, both in the psychotic and cognitive symptoms associated with schizophrenia. T...
Source: World of Psychology - February 8, 2019 Category: Psychiatry & Psychology Authors: John M. Grohol, Psy.D. Tags: Alternative and Nutritional Supplements Disorders General Research Treatment cannabidiol Cannabis cbd cbd oil Marijuana THC Source Type: blogs

New Findings “Lend Confidence” To The Idea That Cortical Blindness Eliminates The Risk Of Developing Schizophrenia
Not a single case of schizophrenia has ever been reported in someone who is cortically blind, according to the authors of a new population-wide study into the phenomenon By Emma Young Various visual impairments and abnormalities, such as unusual eye movement patterns, blink rates and retinal problems, are more common than usual in people diagnosed with schizophrenia, suggesting these issues may contribute to the development of the condition. Yet paradoxically, since the 1950s, there have also been intriguing hints that people who are blind from birth or an early age are less likely to develop schizophrenia and other kinds ...
Source: BPS RESEARCH DIGEST - January 25, 2019 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: Brain Psychosis Source Type: blogs

Glaucous Gull, Larus hyperboreus
The Glaucous Gull (Larus hyperboreus) is the world’s second largest gull (largest is the Great Black-backed Gull (Larus marinus). It breeds in The Arctic but we do see them further south. My photograph is of a first winter youngster. It is feeding on seal blubber on the beach way East of the beach carpark at Cley-next-the-sea in North Norfolk (we saw a few dead seals on the beach on this visit perhaps battered in yesterday’s high winds and rough seas). The word “glaucous” is descriptive of the adult bird’s colour. It simply means “dull bluish-green, gray,” but somehow that came fr...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 18, 2019 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs

Juvenile Glaucous Gull, Larus hyperboreus
The Glaucous Gull (Larus hyperboreus) is the world’s second largest gull (largest is the Great Black-backed Gull (Larus marinus). It breeds in The Arctic but we do see them further south. My photograph is of a first winter youngster, juvenile gull. It is feeding on seal blubber on the beach way East of the beach carpark at Cley-next-the-Sea in North Norfolk (we saw a few dead seals on the beach on this visit perhaps battered in yesterday’s high winds and rough seas). The word “glaucous” is descriptive of the adult bird’s colour. It simply means “dull bluish-green, gray,” but someh...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 18, 2019 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs

Test your Glaucoma Eye Q
January is Glaucoma Awareness Month, and while you’re crossing your T’s and dotting your I’s (wink wink) on those New Year’s Resolutions, consider completing the Glaucoma Eye Q Test from PreventBlindness.Org .  The site contains a list of several downloadable and printable fact sheets, including Common Eye Myths and tips for finding and visiting with an eye care doctor.  The National Eye Health Education Program (NEHEP) encourages people to add a dilated eye exam to your list and help prevent vision loss from a disease that often has no symptoms in the early stages.  NEHEP también tiene información en español...
Source: BHIC - January 10, 2019 Category: Databases & Libraries Authors: Nora Franco Tags: General consumer health glaucoma New Year's Resolutions Source Type: blogs

Acute Angle Closure: Mastering Tonometry
​Identifying and managing disease often requires the delicate and skillful use of temperamental emergency department machinery. The ability to apply these may appropriately help determine a difficult diagnosis.Glaucoma, we all know, can cause blindness, and acute narrow angle glaucoma refers to the angles within the eye that are not as wide and open as normal. People with acute angle glaucoma have abnormal anatomy within the eye where the angle changes as the eye is dilated. This can cause blockages of fluid drainage from the anterior to posterior changes resulting in increased intraocular pressure. It ca lead to acute a...
Source: The Procedural Pause - November 9, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Glaucoma Drainage Device Uses Magnetic Fields for Self-Cleaning
Researchers at Purdue University have designed a prototype glaucoma drainage device that can clean itself under the influence of external magnetic waves. The innovation could lead to ocular drainage implants that last significantly longer than current models. The CDC has reported that approximately three million Americans are living with glaucoma. At present, clinicians prescribe medications, or advise that patients undergo surgical implantation of a drainage device to relieve the pressure build-up in the eye and restore sight. However, these approaches offer varying degrees of success. One of the problems is that implanta...
Source: Medgadget - November 9, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Materials Ophthalmology Source Type: blogs

An Ophthalmologist In Your Kitchen – The EyeQue Insight Review
Easy-to-use, accessible and relatively low-cost solution for a widely experienced problem: these are my favorite digital health innovations. EyeQue Insight lets anyone test their vision at home so people living in rural areas, with special needs or no access to transportation could still make sure they have the necessary sight test from time to time. Here’s our EyeQue Insight review. Have you seen the numbers? What about the letters? Eye problems are global phenomena: the World Health Organisation estimates that approximately 1.3 billion people live with some form of vision impairment. That means on average at least one ...
Source: The Medical Futurist - November 8, 2018 Category: Information Technology Authors: nora Tags: Health Sensors & Trackers Medical Professionals Patients eye eye test future home Innovation ophthalmology review technology testing vision Source Type: blogs

Drug Releasing Contact Lens Changes Color to Show When Its Working
Drugs designed to treat eye conditions are often delivered via eye drops. Almost all of the actual drug ends up dripping off the eye and not being properly absorbed. Drug releasing contact lenses are the next big thing to treat conditions such as glaucoma, and they may end up being pretty smart in addition to being good drug delivery methods. Scientists at the Southeast University and China Pharmaceutical University, both in Nanjing, China, have developed a contact lens that can release a drug into the eye and also report on the status of that release. The contact lens changes color as the drug is released, but only in th...
Source: Medgadget - October 12, 2018 Category: Medical Devices Authors: Editors Tags: Materials Medicine Ophthalmology Source Type: blogs

MKSAP: 49-year-old woman with obesity, hypertension, and type 2 diabetes mellitus
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians. A 49-year-old woman is evaluated during a follow-up visit. She is overweight and has hypertension and type 2 diabetes mellitus, both of which are well controlled. For several years, she has attempted to lose weight through various commercial diets; dietician-monitored, calorie-restricted diets; and physical activity. She has worked with a behavioral therapist, and although she has not achieved weight loss, her weight has remained stable. She exercises 30 minutes daily. Medical history is also remarkable for glau...
Source: Kevin, M.D. - Medical Weblog - September 1, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Obesity Primary Care Source Type: blogs

Fight Aging! Newsletter, August 20th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - August 19, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

RightEye Vision Tests with Contextualized Results: Review and Interview
In conclusion, I really enjoyed the opportunity to use the RightEye system. Working with Dr. Kungle and the RightEye system resulted in the most comprehensive, informative session I’ve ever had about my own vision and left me with clear areas to improve, as well as some initial tools to realize that improvement. Interview with Dr. Kungle Mike Batista, Medgadget: How did you initially engage with RightEye? Dr. Jennifer Kungle: My engagement with the team at RightEye began as part of an initiative for better vision screenings in schools. Most vision screeners just look at acuity, but patients can still have vision p...
Source: Medgadget - August 16, 2018 Category: Medical Devices Authors: Michael Batista Tags: Exclusive Neurology Neurosurgery Ophthalmology Source Type: blogs