An eye surgeon ’ s unexpected finding: a brain tumor diagnosis
In medicine, the sickest patients always seem to come on Friday afternoons. At the end of the week, I’m hoping to move quickly through my last few patients – a small corneal abrasion, a routine follow-up, or a stable glaucoma exam. I’m prepared for a pleasant conversation and some friendly banter about rival football teams Read more… An eye surgeon’s unexpected finding: a brain tumor diagnosis originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 12, 2023 Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Source Type: blogs

Beta-Blockers For High Blood Pressure: Types, Side Effects, Drug Interactions
Conclusion In conclusion, beta-blockers serve as an indispensable tool in the realm of modern medical treatment, particularly in managing a broad range of cardiovascular conditions. Their unique mechanism of action, which includes decreasing heart rate and blood pressure, confers a significant cardio-protective effect. This, combined with their versatility and the extensive clinical experience with their use, has cemented beta-blockers as a first-line treatment for various conditions, from hypertension and heart failure to anxiety and migraines. Although beta-blockers present unique benefits, it’s crucial...
Source: The EMT Spot - July 24, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

27 Dangers And Risks Of High Blood Pressure
Conclusion Despite its silent nature, high blood pressure gradually damages organs over time. The interconnectedness of the circulatory system means that all organs reachable by blood are at risk. Hypertension can lead to critical complications such as heart enlargement, coronary artery disease, stroke, cognitive decline, erectile dysfunction, kidney disease, proteinuria, vision problems, and vascular damage. The importance of proactive measures to manage and prevent these adverse effects is emphasized. Regular blood pressure monitoring, adopting a healthy lifestyle, and working with healthcare professionals ar...
Source: The EMT Spot - June 1, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Dangers And Risks Of High Blood Pressure
Conclusion Despite its silent nature, high blood pressure gradually damages organs over time. The interconnectedness of the circulatory system means that all organs reachable by blood are at risk. Hypertension can lead to critical complications such as heart enlargement, coronary artery disease, stroke, cognitive decline, erectile dysfunction, kidney disease, proteinuria, vision problems, and vascular damage. The importance of proactive measures to manage and prevent these adverse effects is emphasized. Regular blood pressure monitoring, adopting a healthy lifestyle, and working with healthcare professionals ar...
Source: The EMT Spot - June 1, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, May 8th 2023
In conclusion, NAT mitigated age-associated cerebral injury in mice through gut-brain axis. The findings provide novel evidence for the effect of NAT on anti-aging, and highlight the potential application of NAT as an effective intervention against age-related diseases. Retinal Cell Reprogramming Restores Vision in Non-Human Primate Study https://www.fightaging.org/archives/2023/05/retinal-cell-reprogramming-restores-vision-in-non-human-primate-study/ Early applications of in vivo cellular reprogramming to medicine are cautiously focused on retinal regeneration. The eye is as close to an isolated system...
Source: Fight Aging! - May 7, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Retinal Cell Reprogramming Restores Vision in Non-Human Primate Study
Early applications of in vivo cellular reprogramming to medicine are cautiously focused on retinal regeneration. The eye is as close to an isolated system as one is going to find in the body, and only small amounts of a gene therapy vector are required for effective delivery. This very localized, comparatively isolated therapy bypasses or minimizes many of the technical concerns and areas of uncertainty regarding reprogramming, allowing those who are focused on pushing applications to the clinical to forge ahead. The more interesting applications remain those in which reprogramming factors are delivered systemically to muc...
Source: Fight Aging! - May 1, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, April 10th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 9, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards An Aging Clock Based on Retinal Imaging of the Microvasculature
Blood vessel density declines with age, alongside other detrimental changes in the microvasculature, such as small areas of tissue damage following microbleeds. All of this can be readily imaged in the retina, and retinal imaging is already in widespread use in clinical practices. Thus it is interesting to see progress towards an aging clock that uses this aspect of degenerative aging as a marker. A number of potential therapeutic strategies may meaningfully increase angiogenesis and thus microvascular density in later life, such as increased circulating VEGF via gene therapy, or use of existing FDA-approved CLCX12 agonist...
Source: Fight Aging! - April 6, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

What Tends to Go Wrong With Medication Adherence?
This article looks at special conditions that weren’t covered in previous articles. Interventions Must Be Tailored Reminders lie at the core of many IT solutions to medication adherence. But a mechanistic delivery of generic messages with no particular appeal to a patient’s needs and values will usually be a waste. As Bryan Hill, VP of digital health and innovation at Cognizant, says, “Nudge, but don’t nag.” I am personally annoyed by the messages my pharmacy and insurance company send me to remind me to order my medication. These messages arrive when a couple months of my current prescription...
Source: EMR and HIPAA - April 5, 2023 Category: Information Technology Authors: Andy Oram Tags: Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC AristaMD Babylon Health Bethany Doran Bryan Hill Carium Cognizant Colin Banas DrFirst Source Type: blogs

What is the role of Disopyramide in HCM?
Disopyramide is a class Ia antiarrhythmic agent which can be used in hypertrophic obstructive cardiomyopathy when beta blockers alone are ineffective. Disopyramide has a negative inotropic action and is useful in reducing left ventricular outflow tract gradients in hypertrophic obstructive cardiomyopathy and does not increase the risk of sudden cardiac death. Dose reduction is recommended when QTc exceeds 480 ms. It should be avoided in those with glaucoma and men with prostatic symptoms in view of its anticholinergic action. Anticholinergic action is responsible for increase in ventricular rate with atrial fibrillation. ...
Source: Cardiophile MD - November 24, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Cigna-Express Scripts by InsideRx Strategy Modification, Mark Cuban Cost Plus Insulin Trial
Two years ago, I made a very well-informed decision to simply bypass our own healthcare insurance for a number of prescriptions used in my household because we were paying out-of-pocket until the deductible was satisfied anyway (which was about half the year), and our new insurance carrier Aetna and its PBM Caremark was obviously ripping us off by a fairly wide margin. In fact, the financial gamesmanship (or as the PBM ' s call it, " Price Arbitrage " ) was so overt, that it would have been financially foolish to stick with insurance under the presumption that it contributed toward satisfying the deductible (a falsehood; t...
Source: Scott's Web Log - November 21, 2022 Category: Endocrinology Tags: 2022 CIGNA coupon-generating websites apps coupons Express Scripts InsideRx PBM Source Type: blogs

AI Startup AESOP Raises $3M to Tackle Medical and Billing Errors
Digital health startup AESOP Technology has raised a $2.95 million series pre-A round to address the growing medical and billing errors problem. The round was led by Taiwania Capital with participation from Colopl Next, 500 Startups, and BE Capital. Originally from Taiwan, AESOP started as a university spin-off from Taipei Medical University (TMU). Professor Yu Chuan (Jack) Li, the founder and current president at the International Medical Informatics Association, spent ten years before AESOP working on big data approaches to reduce medication errors. He initially applied the model to launch a product, RxPrime (previo...
Source: EMR and HIPAA - September 13, 2022 Category: Information Technology Authors: Healthcare IT News Tags: AI/Machine Learning Health IT Company Healthcare IT 500 Startups AESOP AESOP Technology BE Capital Colopl Next Dr. Jeremiah Scholl Dr. Jim Long DxPrime Health IT Funding Health IT Fundings Health IT Investment International Med Source Type: blogs

Open-angle glaucoma: To screen or not to screen? [PODCAST]
Subscribe to The Podcast by KevinMD.“My take on the Task Force statement is that clinical judgment should rule as to whether or not screening is indicated for glaucoma. Family history, race, diabetes, and other risk factors should be considered for such screening, especially in the face of potential asymptomatic damage. How often have doctorsRead more …Open-angle glaucoma: To screen or not to screen? [PODCAST] originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - July 5, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/the-podcast-by-kevinmd" rel="tag" data-wpel-link="internal" > The Podcast by KevinMD < /a > < /span > Tags: Podcast Ophthalmology Source Type: blogs

Open-angle glaucoma: To screen or not to screen?
In a published statement in JAMA Network on May 24/31, 2022, the U.S. Preventive Services Task Force found that there was insufficient evidence for screening for primary open-angle glaucoma in adults. They could not find a way to balance harms versus benefits for screening in general. But is this reasoning faulty? It is well knownRead more …Open-angle glaucoma: To screen or not to screen? originally appeared inKevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 23, 2022 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/post-author/paul-pender" rel="tag" data-wpel-link="internal" > Paul Pender, MD < /a > < /span > Tags: Conditions Ophthalmology Source Type: blogs

TearCare System for Meibomian Gland Dysfunction: Interview with Reay H. Brown, CMO of Sight Sciences
Sight Sciences, a medtech company based in California, specializes in devices to treat glaucoma and dry eye disease. The company has recently announced FDA 510(k) clearance for the TearCare System, a device designed to treat meibomian gland dysfunction. Meibomian glands are present near the rims of our eyelids and they secrete a clear oily substance called meibum that helps to lubricate the eye and reduce the evaporation of tears. When these glands get blocked, as they do in cases of meibomian gland dysfunction, they can no longer secrete meibum. Such blockages are a leading cause of dry eye disease. The TearCare Sys...
Source: Medgadget - January 27, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Ophthalmology Source Type: blogs