3 US Inventors Named 2017 European Inventor Award Finalists
The European Patent Office (EPO) announced its finalists for the 2017 European Inventor Award in the categories of Industry, Research, Non-EPO Countries, Small and Medium-Sized Enterprises, and Lifetime Achievement. The Award, begun in 2006, aims to pay “tribute to the creativity of inventors the world over, who use their technical, scientific and intellectual skills to make a real contribution to technological progress and economic growth and so improve people’s daily lives.” While any member of the public can nominate someone for the award, the EPO and an international jury evaluate submissions based o...
Source: Medgadget - April 26, 2017 Category: Medical Equipment Authors: Michael Batista Tags: News Source Type: blogs

April in Paris: Voyager Avec Enfants (Day Six)
The theme of day 6 was:less fartsy, more artsy.The second guided tour I planned for this trip was a family experience for the Louvre. Because the thing is, I was pretty close to skipping the Louvre on this trip entirely. Cal would have been in the bag for it (to a degree), and Mack may have been interested to see the Mona Lisa and a few other pieces of art that he recognized, though not that much beyond that. But Nina, I thought, was not the right age at all for a classic art museum. Too big, not interactive enough, too many people in the way, too many queues, too much walking--it would all have translated into: " When are...
Source: the underwear drawer - April 8, 2017 Category: Anesthesiology Authors: Michelle Au Source Type: blogs

Fight Aging! Newsletter, April 3rd 2017
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - April 2, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

A Popular Science Article on Treating Aging as a Medical Condition
This article is above average, but that is a low bar to pass at the moment. Wander down a supplement aisle at your local pharmacy or hop on the internet, and it's not hard to find products that promise to "slow the normal signs of aging" or that offer "long-term well-being at the cellular level." Humans have been trying to outsmart the inevitable for centuries. After hundreds of years of effort, there is still no miracle pill that can turn back time, despite the claims of zealous entrepreneurs. Some pseudoaging treatments over the years have been risky, capable of doing more harm than good. Others have just yielde...
Source: Fight Aging! - March 7, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The way forward
Royal College of Opthamologists (RCOpth) - These reports were commissioned by RCOpth to identify current methods of working and schemes devised by ophthalmology departments in the UK to help meet the increasing demand in ophthalmic services. The work found that increasing demand for hospital eye services is not being met and continues to grow – currently seeing nearly ten per cent of all outpatient appointments and performing six per cent of the surgery in the UK. Each report focuses on an area of high volume within opthalmic care: cataracts, glaucoma, emergency eye care, and age-related macular degeneration and di...
Source: Health Management Specialist Library - February 5, 2017 Category: UK Health Authors: The King ' s Fund Information & Knowledge Service Tags: Local authorities, public health and health inequalities NHS measurement and performance Source Type: blogs

More Evidence for Exosomes to be Important in the Outcome of Stem Cell Therapies
Stem cell therapies produce benefits, but for most of the presently available treatments this appears to be the result of changes in the signaling environment rather than any other activity on the part of the transplanted cells. The newly introduced stem cells fail to integrate with local tissues and typically don't last long after transplantation. So what exactly produces the observed beneficial changes in cellular behavior, level of inflammation, and degree of regeneration? There are no doubt many distinct mechanisms, as nothing is ever simple when it comes to cell biology, but of late researchers have focused on a role ...
Source: Fight Aging! - January 27, 2017 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Cool Tools: Pushing the Limits of High-Resolution Microscopy
Cell biologists would love to shrink themselves down and actually see, touch and hear the inner workings of cells. Because that’s impossible, they have developed an ever-growing collection of microscopes to study cellular innards from the outside. Using these powerful tools, researchers can exhaustively inventory the molecular bits and pieces that make up cells, eavesdrop on cellular communication and spy on cells as they adapt to changing environments. In recent years, scientists have developed new cellular imaging techniques that allow them to visualize samples in ways and at levels of detail never before possible....
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - January 24, 2017 Category: Research Authors: Alisa Zapp Machalek Tags: Cell Biology Cells Cellular Processes Cool Tools/Techniques Electron Microscopy Source Type: blogs

TechTool Thursday 070 D-Eye
TechTool review – D-Eye the ophthalmoscope for iPhones Website:  – Facebook – iTunes – LinkedIn – Twitter – Website D-eye is a smartphone solution to ophthalmoscopy, it converts your iPhone into a digital ophthalmoscope with the ability to either take still shots or record examinations in high definition. The examinations can then be stored securely in a cloud and shared with experts if required. Design The app has undergone some important changes since I was first given this product. It now has the option of fast secure login with touch-id. The home screen gives you access to y...
Source: Life in the Fast Lane - November 24, 2016 Category: Emergency Medicine Authors: Neil Long Tags: Review Tech Tool d-eye digital ophthalmoscopy tech tool thursday Source Type: blogs

Mitochondrial Antioxidant SkQ1 as a Treatment for Age-Related Dry Eye Syndrome
The mitochondrially targeted antioxidant SkQ1 and other compounds in its family have moved into commercial development in Europe. Over the past decade these plastoquinone derivatives have been shown to modestly slow aging in flies and mice, but the greatest and most reliable effects involve reduction of inflammation and effective treatment of inflammatory eye conditions. Thus clinical development has focused on diseases such as dry eye syndrome, an unpleasant condition caused by age-related dysfunction of the lacrimal gland responsible for tear secretion. Aging eventually causes problems in every bodily system, including t...
Source: Fight Aging! - November 21, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Lighting Up the Promise of Gene Therapy for Glaucoma
Retinal ganglion cells in the mouse retina that do (yellow) and do not (blue) contain a specific gene that scientists introduced with a virus. Credit: Kenyoung (“Christine”) Kim, Wonkyu Ju and Mark Ellisman, National Center for Microscopy and Imaging Research, University of California, San Diego. What looks like the gossamer wings of a butterfly is actually the retina of a mouse, delicately snipped to lay flat and sparkling with fluorescent molecules. Researchers captured this image while investigating the promise of gene therapy for glaucoma, a progressive eye disease. It all happened at the National Center for Micro...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - November 2, 2016 Category: Research Authors: Alisa Zapp Machalek Tags: Cell Biology Cells Cellular Imaging Cellular Processes Cool Images Source Type: blogs

Fight Aging! Newsletter, October 3rd 2016
In conclusion, in order to allow faithful and meaningful discoveries, future analysis of iPSCs and their derivatives should not shy away from mitochondrial genome monitoring and single-cell technology. A Copy of the Self: Today's Airy Philosophy is Tomorrow's Practical Concern https://www.fightaging.org/archives/2016/09/a-copy-of-the-self-todays-airy-philosophy-is-tomorrows-practical-concern/ The march of technology turns matters of philosophy into matters of practical action. The process of taking visions and making them concrete makes once airy hypotheticals relevant in everyday life. The theoria of t...
Source: Fight Aging! - October 2, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

WOMEN ’S BRAIN HEALTH SERIES: Diverse Women in Clinical Trials—We Can Make a Difference
Today we wrap up our Disruptive Women WOMEN’S BRAIN HEALTH SERIES with a post by FDA’s Marsha Henderson.  Clinical research will play an important role in helping to advance our understanding of Alzheimer’s disease and dementia in women. During my 20+ year career at the FDA Office of Women’s Health, I have seen improvements in women’s overall participation in clinical trials and advancements in clinical research design and recruitment. However, I know that despite this progress our work is not done. Many women are still uninformed about clinical trials or they simply haven’t been asked ...
Source: Disruptive Women in Health Care - September 30, 2016 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Alzheimer’s Disease Health Women Women's Health Source Type: blogs

Alternate Day Fasting Slows Progression of Glaucoma in an Animal Model
Calorie restriction is here demonstrated to slow the progression of glaucoma in a mouse model of the condition, without affecting the rising pressure inside the eye that is usually the cause of harm. It is an interesting demonstration of the way in which the shifts in cellular metabolism that occur with calorie restriction prime cells to be more resistant to a range of stresses that typically cause significant amounts of cell death: Glaucoma is characterized by progressive degeneration of retinal ganglion cells (RGCs) and their axons. We previously reported that loss of glutamate transporters (EAAC1 or GLAST) in m...
Source: Fight Aging! - September 30, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

D-EYE Digital Ophthalmoscope Proving Itself in a Clinical Trial for Diagnosing Glaucoma
Conclusions: Smartphone ophthalmoscopy showed substantial agreement with slit-lamp examination for the estimation of the VCDR. The ubiquitous diffusion of the smartphones, together with their connectivity and portability features, enables an extensive benefit for this technology to be used in glaucoma screening, especially in low-resource settings. Flashbacks: Review of the D-EYE Digital Ophthalmoscope…; A Low-Cost Digital Ophthalmoscope for Your Smartphone [Interview]… Study in Journal of Glaucoma: Comparison of Smartphone Ophthalmoscopy With Slit-Lamp Biomicroscopy for Grading Vertical Cup-to-Disc Ratio̷...
Source: Medgadget - September 22, 2016 Category: Medical Equipment Authors: Editors Tags: Net News Ophthalmology Source Type: blogs

Fight Aging! Newsletter, September 12th 2016
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - September 11, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs