Gastrointestinal Stromal Tumor (GIST) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Whole-lesion iodine map histogram analysis in the risk classification of gastrointestinal stromal tumors: comparison with single-slice iodine concentration measurements
ConclusionsBoth whole-lesion IM histogram analysis and single-slice IC measurement can differentiate LG-GISTs and HG-GISTs with similar diagnostic performances. (Source: Abdominal Imaging)
Source: Abdominal Imaging - March 12, 2024 Category: Radiology Source Type: research

Frequency of Clinically Significant Findings in the Surgical Pathology Specimen Following Laparoscopic Sleeve Gastrectomy and Concordance with Preoperative Endoscopy: Insights from a Large Single-Center Experience
ConclusionThis is one of the largest studies describing clinically significant postoperative pathology after SG. AMAG, in particular, is of particular importance as it is associated with a 3 –fivefold increase in risk for gastric cancer. The incidence of significant postoperative pathology in this population is small but potentially clinically significant and requires validation in larger studies. We recommend wider sampling in preoperative endoscopy (body and antrum), especially in p atients being planned for gastric bypass, consideration for routine pathological examination of SG surgical specimens, with careful gross ...
Source: Obesity Surgery - March 12, 2024 Category: Surgery Source Type: research

Reply to comment on predicting the risk stratification of gastrointestinal stromal tumors using machine learning ‑based ultrasound radiomics
(Source: Journal of Medical Ultrasonics)
Source: Journal of Medical Ultrasonics - March 11, 2024 Category: Radiology Source Type: research

Harnessing the supremacy of MEG3 LncRNA to defeat gastrointestinal malignancies
Pathol Res Pract. 2024 Feb 23;256:155223. doi: 10.1016/j.prp.2024.155223. Online ahead of print.ABSTRACTEvidence suggests that long non-coding RNAs (lncRNAs) play a pivotal role in the carcinogenesis and progression of various human malignancies including gastrointestinal malignancies. This comprehensive review reports the functions and mechanisms of the lncRNA maternally expressed gene 3 (MEG3) involved in gastrointestinal malignancies. It summarizes its roles in mediating the regulation of cellular proliferation, apoptosis, migration, invasiveness, epithelial-to-mesenchymal transition, and drug resistance in several gast...
Source: Pathology, Research and Practice - March 7, 2024 Category: Pathology Authors: H H Rashwan A M Taher H A Hassan A A Awaji C J Kiriacos R A Assal R A Youness Source Type: research

GSE241926 Dissection of a CTCF insulator and its impact on chromosome topology and oncogene expression in gastrointestinal stromal tumor (RNA-Seq)
Contributors : Kyung L Kim ; Bradley E BernsteinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensEnhancer-Promoter communication is dependent on the topological organization of genomic DNA, including topologically-associated domains (TADs) and boundaries enforced by the CTCF insulator protein. Here, we characterized the structure and function of the FGF3/4 locus and the boundary element that insulates the region from an enhancer in the adjacent TAD. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - March 6, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

GSE241925 Dissection of a CTCF insulator and its impact on chromosome topology and oncogene expression in gastrointestinal stromal tumor (micro-C)
Contributors : Kyung L Kim ; Bradley E BernsteinSeries Type : OtherOrganism : Homo sapiensEnhancer-Promoter communication is dependent on the topological organization of genomic DNA, including topologically-associated domains (TADs) and boundaries enforced by the CTCF insulator protein. Here, we characterized the structure and function of the FGF3/4 locus and the boundary element that insulates the region from an enhancer in the adjacent TAD. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - March 6, 2024 Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research

GSE241924 Dissection of a CTCF insulator and its impact on chromosome topology and oncogene expression in gastrointestinal stromal tumor (ChIP-Seq)
Contributors : Kyung L Kim ; Bradley E BernsteinSeries Type : Genome binding/occupancy profiling by high throughput sequencingOrganism : Homo sapiensEnhancer-Promoter communication is dependent on the topological organization of genomic DNA, including topologically-associated domains (TADs) and boundaries enforced by the CTCF insulator protein. Here, we characterized the structure and function of the FGF3/4 locus and the boundary element that insulates the region from an enhancer in the adjacent TAD. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - March 6, 2024 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research

Mechanisms of splenic metastasis in gastrointestinal stromal tumors
Asian J Surg. 2024 Mar 4:S1015-9584(24)00382-8. doi: 10.1016/j.asjsur.2024.02.120. Online ahead of print.NO ABSTRACTPMID:38443254 | DOI:10.1016/j.asjsur.2024.02.120 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - March 5, 2024 Category: Surgery Authors: Shengjin Wang Feng Sun Xinghong Wang Source Type: research

Preoperative differentiation of gastric schwannomas and gastrointestinal stromal tumors based on computed tomography: a retrospective multicenter observational study
ConclusionThe proposed nomogram model based on CT imaging features can be used to differentiate gastric schwannoma from GIST before surgery. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - March 5, 2024 Category: Cancer & Oncology Source Type: research

Uncommon Mimicker of a High-Grade Thyroid Carcinoma: Solitary Thyroid Metastasis of Gastrointestinal Stromal Tumor (GIST)
(Source: Endocrine Pathology)
Source: Endocrine Pathology - March 5, 2024 Category: Pathology Source Type: research

Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution
Cell Death & Disease, Published online: 05 March 2024; doi:10.1038/s41419-024-06571-3Deciphering the tumor immune microenvironment of imatinib-resistance in advanced gastrointestinal stromal tumors at single-cell resolution (Source: Cell death and disease)
Source: Cell death and disease - March 5, 2024 Category: Internal Medicine Authors: Xuechao Liu Jing Yu Yi Li Hailei Shi Xuelong Jiao Xiaodong Liu Dong Guo Zequn Li Yulong Tian Fan Dai Zhaojian Niu Yanbing Zhou Source Type: research