Gastrointestinal Stromal Tumor (GIST) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Giant exophytic gastrointestinal stromal tumor (GIST) causing gastric outlet obstruction: case report and review of literature
We present the case of a middle-aged patient diagnosed with a giant gastric GIST, which presented for intermittent gastric outlet obstruction symptoms, and emphasize the major imagistic, histopathological, and therapeutic challenges that may be encountered. There are only several cases of gastric exophytic gastric GIST provoking intermittent gastric outlet obstruction. Tumor resection should be adapted to every patient's status, focused on en bloc extraction, with preservation of invaded organs as much as possible.PMID:38184841 | PMC:PMC10863695 | DOI:10.47162/RJME.64.4.17 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Victor Mihai Sacerdo ţianu Cecil Sorin Mirea Petric ă Popa Dan Ionu ţ Gheonea Maria Camelia Foarf ă Marius Matei Daniela Larisa S ăndulescu Cristian Virgil Lungulescu Tudorel Ciurea Bogdan Silviu Ungureanu Source Type: research

Solitary fibrous tumor developing in the right retroperitoneal space
In conclusion, the early diagnosis of SFTs is essential in establishing an appropriate treatment. Immunohistochemistry is indispensable in establishing the diagnosis of SFTs.PMID:38184840 | PMC:PMC10863682 | DOI:10.47162/RJME.64.4.16 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Cristian Me şină Cosmin Vasile Obleag ă Mihai C ălin Ciorbagiu Cristin Constantin Vere Drago ş Marian Popescu Florina Carmen Popescu Daniel Alin Cristian Mihaela Iustina Me şină-Botoran Source Type: research

Genomic profiling in GIST: Implications in clinical outcome and future challenges
Neoplasia. 2024 Jan 5;48:100959. doi: 10.1016/j.neo.2023.100959. Online ahead of print.ABSTRACTGastrointestinal Stromal Tumors (GIST) are the most frequent mesenchymal neoplasia of the digestive tract. Genomic alterations in KIT, PDFGRA, SDH, and BRAF genes are essential in GIST oncogenesis. Therefore, the mutations in these genes have demonstrated clinical implications. Tumors with deletions in KIT-exon 11 or duplications in exon 9 are associated with a worse prognosis. In contrast, KIT-exon 11 substitutions and duplications are associated with a better clinical outcome. Moreover, mutations in Kit exon 9 and 11 are action...
Source: Neoplasia - January 6, 2024 Category: Cancer & Oncology Authors: German Calderillo-Ru íz Eloy Andr és Pérez-Yepez Mar ía Alejandra García-Gámez Oliver Millan-Catalan Consuelo D íaz-Romero Paul Ugalde-Silva Rodrigo Salas-Benavides Carlos P érez-Plasencia Berenice Carbajal-L ópez Source Type: research

TRIM21/USP15 balances ACSL4 stability and the imatinib resistance of gastrointestinal stromal tumors
CONCLUSION: These findings demonstrate that the TRIM21 and USP15 control ACSL4 stability to maintain the IM sensitive/resistant status of GIST.PMID:38182686 | DOI:10.1038/s41416-023-02562-x (Source: Cancer Control)
Source: Cancer Control - January 5, 2024 Category: Cancer & Oncology Authors: Zhiwei Cui Haoyu Sun Zhishuang Gao Chao Li Tingting Xiao Yibo Bian Zonghang Liu Tianhao Gu Jianan Zhang Tengyun Li Qianzheng Zhou Zhongyuan He Bowen Li Fengyuan Li Zekuan Xu Hao Xu Source Type: research

TRIM21/USP15 balances ACSL4 stability and the imatinib resistance of gastrointestinal stromal tumors
British Journal of Cancer, Published online: 05 January 2024; doi:10.1038/s41416-023-02562-xTRIM21/USP15 balances ACSL4 stability and the imatinib resistance of gastrointestinal stromal tumors (Source: British Journal of Cancer)
Source: British Journal of Cancer - January 5, 2024 Category: Cancer & Oncology Authors: Zhiwei Cui Haoyu Sun Zhishuang Gao Chao Li Tingting Xiao Yibo Bian Zonghang Liu Tianhao Gu Jianan Zhang Tengyun Li Qianzheng Zhou Zhongyuan He Bowen Li Fengyuan Li Zekuan Xu Hao Xu Source Type: research

Bacteremia from streptococcus constellatus revealing a gastrointestinal stromal tumor
ConclusionsDetection ofSc in blood should raise red flags in clinicians as aggressive clinical presentation are possible. (Source: Gut Pathogens)
Source: Gut Pathogens - January 4, 2024 Category: Microbiology Source Type: research

Colonic gastrointestinal stromal tumor (GIST) presenting with colocolonic intussusception: A rare case report
Can Vet J. 2024 Jan;65(1):25-28.ABSTRACTAn 8-year-old spayed female British bulldog was presented with vomiting, hyporexia, and large-bowel diarrhea. Abdominal ultrasound revealed a focal colonic mass with an intussusception located immediately oral to the mass. The intussusception encompassed the ascending and transverse colon and was non-reducible. Colonic resection and anastomosis were completed to include the intussusception and colonic mass. Histopathological examination of the mass demonstrated a spindle cell neoplasm arising within the muscular wall of the intussuscepted segment that obliterated normal architecture....
Source: The Canadian Veterinary Journal - January 2, 2024 Category: Veterinary Research Authors: Emma Dooley Margaret Stalker Monica Jensen Christopher J Pinard Source Type: research