Gastrointestinal Stromal Tumor (GIST) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Gastric tumours
encompass adenocarcinoma, the most common type, as well as gastrointestinal stromal tumours, neuroendocrine tumours and gastric lymphoma. They are typically difficult to diagnose early as the ‘red flag’ features of gastric cancer tend to be associated with advanced disease. As a result, survival outcomes of gastric cancer are poor, with 5-year survival in the UK currently at 20%. There have been significant breakthroughs in systemic therapy and surgical technology to increase chances of cure and improve survival. (Source: Medicine)
Source: Medicine - January 24, 2024 Category: Internal Medicine Authors: Nikhil M. Patel, Sacheen Kumar Tags: Stomach Source Type: research

Precision Oncology in Soft Tissue Sarcomas and Gastrointestinal Stromal Tumors
Soft tissue sarcomas (STSs), including gastrointestinal stromal tumors (GISTs), are mesenchymal neoplasms with heterogeneous clinical behavior and represent broad categories comprising multiple distinct biologic entities. Multidisciplinary management of these rare tumors is critical. To date, multiple studies have outlined the importance of biological characterization of mesenchymal tumors and have identified key molecular alterations which drive tumor biology. GIST has represented a flagship for targeted therapy in solid tumors with the advent of imatinib which has revolutionized the way we treat this malignancy. Herein, ...
Source: Surgical Oncology Clinics of North America - January 17, 2024 Category: Surgery Authors: Adam M. Fontebasso, Jeffrey D. Rytlewski, Jean-Yves Blay, Rebecca A. Gladdy, Breelyn A. Wilky Source Type: research

Actionable mutational profiling in solid tumors using hybrid ‐capture‐based next‐generation sequencing in a real‐world setting in Spain
ConclusionThis is the largest cohort-level study in Spain to profile the analyses of biopsy samples of different tumors using NGS in routine clinical practice. Our findings showed that the use of NGS routinely provides good rates of informative results and can improve tumor characterization and identify a greater number of actionable mutations. (Source: Cancer Medicine)
Source: Cancer Medicine - January 12, 2024 Category: Cancer & Oncology Authors: Sandra Zazo, Sandra P érez‐Buira, Nerea Carvajal, Jenifer Plaza‐Sánchez, Rebeca Manso, Nuria Pérez‐González, Carolina Dominguez, Iván Prieto‐Potin, Jaime Rubio, Manuel Dómine, Virginia Lozano, Patricia Mohedano, David Carcedo, R Tags: RESEARCH ARTICLE Source Type: research

Gastrointestinal stromal tumor in North Africa and the middle east: updates in presentation and management from an 11-year retrospective cohort
Volume 51, Issue 5, December 2023, Page 275-287 . (Source: Hospital Practice)
Source: Hospital Practice - January 10, 2024 Category: Hospital Management Authors: Fadi FarhatMarwa HusseinEman SbaityAbdullah AlsharmKakil RasulSaad KhairallahTarek AssiNiloofar AllahverdiAhmad OthmanJoseph Kattana Department of Onco-Hematology, Mount Lebanon Hospital University Medical Center, Balamand University, Beirut, Hazmieh, Leb Source Type: research

Retracted: Might Patients with Metastatic Gastrointestinal Stromal Tumors Benefit from Operative Management? A Population-Based Retrospective Study
Biomed Res Int. 2023 Dec 29;2023:9853712. doi: 10.1155/2023/9853712. eCollection 2023.ABSTRACT[This retracts the article DOI: 10.1155/2022/9432410.].PMID:38188840 | PMC:PMC10769750 | DOI:10.1155/2023/9853712 (Source: Biomed Res)
Source: Biomed Res - January 8, 2024 Category: Research Authors: BioMed Research International Source Type: research

Case report: Benign and malignant tumors in adult patients with neurofibromatosis type 1: a comprehensive case series from a large oncologic reference center
ConclusionIn Mexico, patients diagnosed with NF1 develop diverse tumors as adults. As described in other studies, the most frequent malignant tumor in this patient population is the malignant peripheral nerve sheath tumor. Further studies are required to increase the scarce information available for adult Hispanics with NF1. (Source: Frontiers in Oncology)
Source: Frontiers in Oncology - January 8, 2024 Category: Cancer & Oncology Source Type: research

Giant exophytic gastrointestinal stromal tumor (GIST) causing gastric outlet obstruction: case report and review of literature
We present the case of a middle-aged patient diagnosed with a giant gastric GIST, which presented for intermittent gastric outlet obstruction symptoms, and emphasize the major imagistic, histopathological, and therapeutic challenges that may be encountered. There are only several cases of gastric exophytic gastric GIST provoking intermittent gastric outlet obstruction. Tumor resection should be adapted to every patient's status, focused on en bloc extraction, with preservation of invaded organs as much as possible.PMID:38184841 | DOI:10.47162/RJME.64.4.17 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Victor Mihai Sacerdo ţianu Cecil Sorin Mirea Petric ă Popa Dan Ionu ţ Gheonea Maria Camelia Foarf ă Marius Matei Daniela Larisa S ăndulescu Cristian Virgil Lungulescu Tudorel Ciurea Bogdan Silviu Ungureanu Source Type: research

Solitary fibrous tumor developing in the right retroperitoneal space
In conclusion, the early diagnosis of SFTs is essential in establishing an appropriate treatment. Immunohistochemistry is indispensable in establishing the diagnosis of SFTs.PMID:38184840 | DOI:10.47162/RJME.64.4.16 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Cristian Me şină Cosmin Vasile Obleag ă Mihai C ălin Ciorbagiu Cristin Constantin Vere Drago ş Marian Popescu Florina Carmen Popescu Daniel Alin Cristian Mihaela Iustina Me şină-Botoran Source Type: research

Giant exophytic gastrointestinal stromal tumor (GIST) causing gastric outlet obstruction: case report and review of literature
We present the case of a middle-aged patient diagnosed with a giant gastric GIST, which presented for intermittent gastric outlet obstruction symptoms, and emphasize the major imagistic, histopathological, and therapeutic challenges that may be encountered. There are only several cases of gastric exophytic gastric GIST provoking intermittent gastric outlet obstruction. Tumor resection should be adapted to every patient's status, focused on en bloc extraction, with preservation of invaded organs as much as possible.PMID:38184841 | PMC:PMC10863695 | DOI:10.47162/RJME.64.4.17 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Victor Mihai Sacerdo ţianu Cecil Sorin Mirea Petric ă Popa Dan Ionu ţ Gheonea Maria Camelia Foarf ă Marius Matei Daniela Larisa S ăndulescu Cristian Virgil Lungulescu Tudorel Ciurea Bogdan Silviu Ungureanu Source Type: research

Solitary fibrous tumor developing in the right retroperitoneal space
In conclusion, the early diagnosis of SFTs is essential in establishing an appropriate treatment. Immunohistochemistry is indispensable in establishing the diagnosis of SFTs.PMID:38184840 | PMC:PMC10863682 | DOI:10.47162/RJME.64.4.16 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Cristian Me şină Cosmin Vasile Obleag ă Mihai C ălin Ciorbagiu Cristin Constantin Vere Drago ş Marian Popescu Florina Carmen Popescu Daniel Alin Cristian Mihaela Iustina Me şină-Botoran Source Type: research

Giant exophytic gastrointestinal stromal tumor (GIST) causing gastric outlet obstruction: case report and review of literature
We present the case of a middle-aged patient diagnosed with a giant gastric GIST, which presented for intermittent gastric outlet obstruction symptoms, and emphasize the major imagistic, histopathological, and therapeutic challenges that may be encountered. There are only several cases of gastric exophytic gastric GIST provoking intermittent gastric outlet obstruction. Tumor resection should be adapted to every patient's status, focused on en bloc extraction, with preservation of invaded organs as much as possible.PMID:38184841 | PMC:PMC10863695 | DOI:10.47162/RJME.64.4.17 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Victor Mihai Sacerdo ţianu Cecil Sorin Mirea Petric ă Popa Dan Ionu ţ Gheonea Maria Camelia Foarf ă Marius Matei Daniela Larisa S ăndulescu Cristian Virgil Lungulescu Tudorel Ciurea Bogdan Silviu Ungureanu Source Type: research

Solitary fibrous tumor developing in the right retroperitoneal space
In conclusion, the early diagnosis of SFTs is essential in establishing an appropriate treatment. Immunohistochemistry is indispensable in establishing the diagnosis of SFTs.PMID:38184840 | PMC:PMC10863682 | DOI:10.47162/RJME.64.4.16 (Source: Romanian Journal of Morphology and Embryology)
Source: Romanian Journal of Morphology and Embryology - January 7, 2024 Category: General Medicine Authors: Cristian Me şină Cosmin Vasile Obleag ă Mihai C ălin Ciorbagiu Cristin Constantin Vere Drago ş Marian Popescu Florina Carmen Popescu Daniel Alin Cristian Mihaela Iustina Me şină-Botoran Source Type: research