UnitedHealthcare Extends Coverage to Abbott ’s Unique Neurostimulation Therapy for Nerve Pain
- Abbott ’s Proclaim™ dorsal root ganglion (DRG) neurostimulation system is the only FDA-approved DRG technology for the treatment of CRPS I and causalgia of the lower extremitiesi (Source: Abbott.com)
Source: Abbott.com - February 3, 2022 Category: Pharmaceuticals Source Type: news
TRPV1 and Migraines
Conclusion-the present findings indicate that insulin may activate TRPV1 receptors in the trigeminovascular system. Modified TRPV1 receptor function induced by insulin may also increase the sensitivity of both neural and vascular TRPV1 receptor for its agonists. Our data may provide a pathophysiological basis for the increased incidence of migraine in patients with hyperinsulin levels. (Source: Neuromics)
Source: Neuromics - January 21, 2022 Category: Neuroscience Source Type: news
How Do You Get Rid of a Ganglion Cyst on Your Foot?
Title: How Do You Get Rid of a Ganglion Cyst on Your Foot?Category: Diseases and ConditionsCreated: 8/18/2021 12:00:00 AMLast Editorial Review: 8/18/2021 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - August 18, 2021 Category: Rheumatology Source Type: news
What Is the Best Treatment for a Ganglion Cyst?
Title: What Is the Best Treatment for a Ganglion Cyst?Category: Diseases and ConditionsCreated: 8/10/2021 12:00:00 AMLast Editorial Review: 8/10/2021 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - August 10, 2021 Category: Dermatology Source Type: news
Stellate Ganglion Phototherapy Promising for Electrical Storm Stellate Ganglion Phototherapy Promising for Electrical Storm
SG phototherapy reduced sympathetic activity and might be a useful temporary adjunctive therapy to control electrical storm, a pilot study finds.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - July 8, 2021 Category: Cardiology Tags: Cardiology News Source Type: news
The retinal ganglion cell response to blast-mediated traumatic brain injury is genetic background dependent - Harper MM, Boehme N, Dutca LM, Anderson MG.
PURPOSE: The purpose of this study was to examine the influence of genetic background on the retinal ganglion cell (RGC) response to blast-mediated traumatic brain injury (TBI) in Jackson Diversity Outbred (J:DO), C57BL/6J and BALB/cByJ mice. METHO... (Source: SafetyLit)
Source: SafetyLit - June 11, 2021 Category: International Medicine & Public Health Tags: Burns, Electricity, Explosions, Fire, Scalds Source Type: news
Trigeminal Neuralgia (Facial Pain)
Markers for Pain ResearchTrigeminal Neuralgia is a progress chronic condition. Dysfunctional trigeminal signaling can lead to intense, searing facial pain. It is caused by pressure on the trigeminal nerve.The root causes of the condition are not well understood. Ourpain research markers have been widely used and frequently published through the years and have been important contributors to our growth, Here ' s a recent pub referencing use of one ourP2X3 Antibodies-Momoko Koizumi, Sayaka Asano, Akihiko Furukawa, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Katsuhiko Hayashi, Fusao Kato, Koichi Iwata, and Masamichi...
Source: Neuromics - May 27, 2021 Category: Neuroscience Tags: Craniofacial pain P2X3 Antibody P2X3 Receptor Antibody Trigeminal Neurons Source Type: news
AI spots neurons better than human experts
(Duke University) A combination of optical coherence tomography (OCT), adaptive optics and deep neural networks can easily and precisely track changes in the number and shape of retinal ganglion cells in the eye. This new AI-driven method can enable better diagnosis and monitoring for neuron-damaging eye and brain diseases like glaucoma. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 25, 2021 Category: International Medicine & Public Health Source Type: news
Man Blind for 40 Years Regains Some Sight Through Gene Therapy
MONDAY, May 24, 2021 -- Doctors for the first time have used a form of gene therapy to restore partial vision in a blind person, according to findings announced Monday.
The research team genetically altered retinal ganglion cells to become... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 24, 2021 Category: General Medicine Source Type: news
Bilateral visual projections exist in non-teleost bony fish and predate the emergence of tetrapods
In most vertebrates, camera-style eyes contain retinal ganglion cell neurons that project to visual centers on both sides of the brain. However, in fish, ganglion cells were thought to innervate only the contralateral side, suggesting that bilateral visual projections appeared in tetrapods. Here we show that bilateral visual projections exist in non-teleost fishes and that the appearance of ipsilateral projections does not correlate with terrestrial transition or predatory behavior. We also report that the developmental program that specifies visual system laterality differs between fishes and mammals, as the Zic2 transcri...
Source: ScienceNOW - April 8, 2021 Category: Science Authors: Vigouroux, R. J., Duroure, K., Vougny, J., Albadri, S., Kozulin, P., Herrera, E., Nguyen-Ba-Charvet, K., Braasch, I., Suarez, R., Del Bene, F., Chedotal, A. Tags: Evolution, Neuroscience r-articles Source Type: news
A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets
In the peripheral nervous system, ligand-receptor interactions between cells and neurons shape sensory experience, including pain. We set out to identify the potential interactions between sensory neurons and peripheral cell types implicated in disease-associated pain. Using mouse and human RNA sequencing datasets and computational analysis, we created interactome maps between dorsal root ganglion (DRG) sensory neurons and an array of normal cell types, as well as colitis-associated glial cells, rheumatoid arthritis–associated synovial macrophages, and pancreatic tumor tissue. These maps revealed a common correlation...
Source: Signal Transduction Knowledge Environment - March 16, 2021 Category: Science Authors: Wangzhou, A., Paige, C., Neerukonda, S. V., Naik, D. K., Kume, M., David, E. T., Dussor, G., Ray, P. R., Price, T. J. Tags: STKE Research Resources Source Type: news
Abbott to Launch the NeuroSphere(TM) myPath(TM) Digital Health App Designed to Track and Report Pain Relief in Chronic Pain Patients With Physicians Prior to Device Implant
New app will allow patients to record their pain relief during the device trial period with spinal cord stimulation or dorsal root ganglion therapy, simplify reporting outcomes and connect patients to physicians who have real-time access to this data
Ne... Devices, Neurology, Monitoring, Product Launch Abbott, NeuroSphere, myPath, spinal cord stimulation, neuromodulation (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - January 14, 2021 Category: Pharmaceuticals Source Type: news
Abbott to Launch the NeuroSphere ™ myPath™ Digital Health App Designed to Track and Report Pain Relief in Chronic Pain Patients With Physicians Prior to Device Implant
- New app will allow patients to record their pain relief during the device trial period with spinal cord stimulation or dorsal root ganglion therapy, simplify reporting outcomes and connect patients to physicians who have real-time access to this data (Source: Abbott.com)
Source: Abbott.com - January 14, 2021 Category: Pharmaceuticals Source Type: news
Sex does not influence visual outcomes after blast-mediated traumatic brain injury but IL-1 pathway mutations confer partial rescue - Evans LP, Boehme N, Wu S, Burghardt EL, Akurathi A, Todd BP, Newell EA, Ferguson PJ, Mahajan VB, Dutca LM, Harper MM, Bassuk AG.
PURPOSE: In a mouse model of blast-mediated traumatic brain injury (bTBI), interleukin-1 (IL-1)-pathway components were tested as potential therapeutic targets for bTBI-mediated retinal ganglion cell (RGC) dysfunction. Sex was also evaluated as a variable ... (Source: SafetyLit)
Source: SafetyLit - October 14, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Toxicity of dorsal root ganglia is widely associated with CNS AAV gene therapy
(Mary Ann Liebert, Inc./Genetic Engineering News) A meta-analysis of non-human primate (NHP) studies showed that adeno-associated virus (AAV) gene therapy often caused dorsal root ganglion (DRG) pathology. There were no clinical effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 2, 2020 Category: International Medicine & Public Health Source Type: news
