Clinical Significance of Frequently Down-Regulated Phosphatidylethanolamine-Binding Protein-1 in Gallbladder Cancer
ConclusionPEBP1 is frequently down-regulated and hypermethylated in gallbladder cancer and its promoter hypermethylation is a frequent and early inactivating mechanism in GBC. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - December 22, 2023 Category: Gastroenterology Source Type: research
Long-lasting complete response to SHR-1701 plus famitinib in refractory advanced gallbladder cancer: A case report
Volume 19, Issue 3, December 2023 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - December 21, 2023 Category: Allergy & Immunology Authors: Lixia YiXiaoyan ZhuJing XieZhiqiang Menga Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai, Chinab Department of Minimally Invasive Therapy Center, Fudan University Shanghai Cancer Center, Shanghai, Chinac Department o Source Type: research
Cancers, Vol. 16, Pages 29: Therapeutic Endoscopic Ultrasound for Complications of Pancreatic Cancer
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Progression of pancreatic adenocarcinoma can result in disease complications such as biliary obstruction and gastric outlet obstruction. The recent advances in endoscopic ultrasound (EUS) have transformed EUS from a purely diagnostic technology to a therapeutic modality, particularly with the development of lumen-apposing metal stents. In terms of biliary drainage, EUS-guided choledochoduodenostomy and EUS-guided hepaticogastrostomy offer safe and effective techniques when conventional transpapillary stent placement via ERCP fails or is not possible. If these modalities are not feasible, EUS-guided gallbladder drai...
Source: Cancers - December 20, 2023 Category: Cancer & Oncology Authors: Samuel Han Georgios I. Papachristou Tags: Review Source Type: research
Deep-learning models for differentiation of xanthogranulomatous cholecystitis and gallbladder cancer on ultrasound
ConclusionSOTA DL models have a better performance than radiologists in differentiating XGC and GBC on the US.Graphical abstract (Source: Indian Journal of Gastroenterology)
Source: Indian Journal of Gastroenterology - December 18, 2023 Category: Gastroenterology Source Type: research
Community cancer screening at primary care level in Northern India: determinants and policy implications for cancer prevention
CONCLUSION: Poor follow-up compliance, despite the availability of tertiary cancer care, patient navigation, free transportation and diagnostic services, calls for research to explore the role of contextual factors and develop pragmatic interventions to justify 'close the care gap'. Community cancer screening needs strengthening through cancer awareness, establishing referral system and integration with the National Tobacco Control and Cancer Registry Programmes.PMID:38105243 | DOI:10.1136/fmch-2023-002397 (Source: Cancer Control)
Source: Cancer Control - December 17, 2023 Category: Cancer & Oncology Authors: Priyanka Sharma Divya Khanna Satyajit Pradhan Praveen Birur Source Type: research
Mucosal damage in pancreaticobiliary maljunction is stronger in the gallbladder than in the bile duct
CONCLUSIONS: Mucosal damage may be involved in carcinogenesis, which may be useful for predicting malignant transformation.PMID:38103363 | DOI:10.1016/j.prp.2023.155011 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - December 16, 2023 Category: Pathology Authors: Masato Kamakura Takeshi Uehara Takashi Muraki Mai Iwaya Shiho Asaka Tomoyuki Nakajima Yugo Iwaya Tadanobu Nagaya Takahiro Yoshizawa Akira Shimizu Yasuhiro Kuraishi Hiroyoshi Ota Takeji Umemura Source Type: research
Mucosal damage in pancreaticobiliary maljunction is stronger in the gallbladder than in the bile duct
CONCLUSIONS: Mucosal damage may be involved in carcinogenesis, which may be useful for predicting malignant transformation.PMID:38103363 | DOI:10.1016/j.prp.2023.155011 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - December 16, 2023 Category: Pathology Authors: Masato Kamakura Takeshi Uehara Takashi Muraki Mai Iwaya Shiho Asaka Tomoyuki Nakajima Yugo Iwaya Tadanobu Nagaya Takahiro Yoshizawa Akira Shimizu Yasuhiro Kuraishi Hiroyoshi Ota Takeji Umemura Source Type: research
Mucosal damage in pancreaticobiliary maljunction is stronger in the gallbladder than in the bile duct
CONCLUSIONS: Mucosal damage may be involved in carcinogenesis, which may be useful for predicting malignant transformation.PMID:38103363 | DOI:10.1016/j.prp.2023.155011 (Source: Pathology, Research and Practice)
Source: Pathology, Research and Practice - December 16, 2023 Category: Pathology Authors: Masato Kamakura Takeshi Uehara Takashi Muraki Mai Iwaya Shiho Asaka Tomoyuki Nakajima Yugo Iwaya Tadanobu Nagaya Takahiro Yoshizawa Akira Shimizu Yasuhiro Kuraishi Hiroyoshi Ota Takeji Umemura Source Type: research
Long non ‑coding RNAs in gallbladder cancer: From mechanisms to therapeutic opportunities (Review)
Int J Oncol. 2024 Feb;64(2):16. doi: 10.3892/ijo.2023.5604. Epub 2023 Dec 15.ABSTRACTDue to the lack of specific symptoms, characteristic diagnostic markers and effective comprehensive treatment, gallbladder cancer (GBC) is currently considered one of the most malignant abdominal tumors. With the rapid development of biological technologies, long non‑coding RNAs (lncRNAs), once regarded as transcriptional junk, have been demonstrated to participate in almost the whole process of the central dogma of molecular biology. The central dogma deals with the transfer of sequential information at the level of individual residues....
Source: International Journal of Oncology - December 15, 2023 Category: Cancer & Oncology Authors: Yingjie He Xuezhi Du Fan Yuan Caigu Yan Ming Chen Lei Han Jinjin Sun Source Type: research
FOLFIRI-bevacizumab as a second-line treatment for advanced biliary tract cancer after gemcitabine-based chemotherapy
CONCLUSION: FOLFIRI-bevacizumab as a second-line treatment for advanced BTC after gemcitabine-based chemotherapy showed efficacy and safety with a promising tumor response rate in this retrospective single-center study.PMID:38098503 | PMC:PMC10720590 | DOI:10.3389/fonc.2023.1293670 (Source: Cancer Control)
Source: Cancer Control - December 15, 2023 Category: Cancer & Oncology Authors: Nicolas Roussot Julie Vincent Remi Palmier Guillaume Constantin Leila Bengrine Jean-David Fumet Fran çois Ghiringhelli Source Type: research
Long non ‑coding RNAs in gallbladder cancer: From mechanisms to therapeutic opportunities (Review)
Int J Oncol. 2024 Feb;64(2):16. doi: 10.3892/ijo.2023.5604. Epub 2023 Dec 15.ABSTRACTDue to the lack of specific symptoms, characteristic diagnostic markers and effective comprehensive treatment, gallbladder cancer (GBC) is currently considered one of the most malignant abdominal tumors. With the rapid development of biological technologies, long non‑coding RNAs (lncRNAs), once regarded as transcriptional junk, have been demonstrated to participate in almost the whole process of the central dogma of molecular biology. The central dogma deals with the transfer of sequential information at the level of individual residues....
Source: International Journal of Oncology - December 15, 2023 Category: Cancer & Oncology Authors: Yingjie He Xuezhi Du Fan Yuan Caigu Yan Ming Chen Lei Han Jinjin Sun Source Type: research
Long non ‑coding RNAs in gallbladder cancer: From mechanisms to therapeutic opportunities (Review)
Int J Oncol. 2024 Feb;64(2):16. doi: 10.3892/ijo.2023.5604. Epub 2023 Dec 15.ABSTRACTDue to the lack of specific symptoms, characteristic diagnostic markers and effective comprehensive treatment, gallbladder cancer (GBC) is currently considered one of the most malignant abdominal tumors. With the rapid development of biological technologies, long non‑coding RNAs (lncRNAs), once regarded as transcriptional junk, have been demonstrated to participate in almost the whole process of the central dogma of molecular biology. The central dogma deals with the transfer of sequential information at the level of individual residues....
Source: International Journal of Oncology - December 15, 2023 Category: Cancer & Oncology Authors: Yingjie He Xuezhi Du Fan Yuan Caigu Yan Ming Chen Lei Han Jinjin Sun Source Type: research
Long non ‑coding RNAs in gallbladder cancer: From mechanisms to therapeutic opportunities (Review)
Int J Oncol. 2024 Feb;64(2):16. doi: 10.3892/ijo.2023.5604. Epub 2023 Dec 15.ABSTRACTDue to the lack of specific symptoms, characteristic diagnostic markers and effective comprehensive treatment, gallbladder cancer (GBC) is currently considered one of the most malignant abdominal tumors. With the rapid development of biological technologies, long non‑coding RNAs (lncRNAs), once regarded as transcriptional junk, have been demonstrated to participate in almost the whole process of the central dogma of molecular biology. The central dogma deals with the transfer of sequential information at the level of individual residues....
Source: International Journal of Oncology - December 15, 2023 Category: Cancer & Oncology Authors: Yingjie He Xuezhi Du Fan Yuan Caigu Yan Ming Chen Lei Han Jinjin Sun Source Type: research
