Cancers, Vol. 16, Pages 989: Sex Differences in Cancer Incidence Rates by Race and Ethnicity: Results from the Surveillance, Epidemiology, and End Results (SEER) Registry (2000 & ndash;2019)
This study investigated sex differences in cancer incidence by race and ethnicity. Cancer incidence data from the Surveillance, Epidemiology, and End Result (SEER) program (2000–2019) were used to calculate male-to-female incidence rate ratios (MF IRRs) for each cancer site, stratified by race and ethnicity, and age-standardized to the 2000 U.S. population for individuals ages ≥ 20 years. Among 49 cancer sites, 44 showed male predominance (MF IRR > 1), with seven inconsistencies across race and ethnicity, including cancers of the lip, tongue, hypopharynx, retroperitoneum, larynx, pleura ...
Source: Cancers - February 29, 2024 Category: Cancer & Oncology Authors: Sararat Tosakoon Wayne R. Lawrence Meredith S. Shiels Sarah S. Jackson Tags: Article Source Type: research
Laparoscopic predictability of minimally invasive interval debulking in advanced ovarian cancer: The MIID-SOC trial
CONCLUSION: This predictive index model may help to guide future inclusion criteria in randomized studies evaluating the MIS approach in advanced epithelial ovarian cancer.PMID:38417209 | DOI:10.1016/j.ygyno.2024.02.019 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - February 28, 2024 Category: Cancer & Oncology Authors: Anthony B Costales Erin K Crane Laura Chambers Meng Yao Danielle Chau Wendel R Naumann Robert Debernardo Stephanie Ricci Peter G Rose Chad M Michener Source Type: research
Laparoscopic predictability of minimally invasive interval debulking in advanced ovarian cancer: The MIID-SOC trial
CONCLUSION: This predictive index model may help to guide future inclusion criteria in randomized studies evaluating the MIS approach in advanced epithelial ovarian cancer.PMID:38417209 | DOI:10.1016/j.ygyno.2024.02.019 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - February 28, 2024 Category: Cancer & Oncology Authors: Anthony B Costales Erin K Crane Laura Chambers Meng Yao Danielle Chau Wendel R Naumann Robert Debernardo Stephanie Ricci Peter G Rose Chad M Michener Source Type: research
Laparoscopic Dissection of Lymph Node Station 16-Why and How?
CONCLUSIONS: While station 16 provides important prognostic information for risk stratification, a strategic and stepwise approach is needed for a safe sampling. This is accomplished by wide mobilization of the duodenum, implementation of thermal fusion to minimize chyle leak, and careful dissection below the left renal vein.PMID:38411760 | DOI:10.1245/s10434-024-15040-2 (Source: Ann Oncol)
Source: Ann Oncol - February 27, 2024 Category: Cancer & Oncology Authors: William Kawahara Eduardo A Vega Omid Salehi Sebastian Mellado Oscar Salirrosas Richard Freeman Elena Panettieri Claudius Conrad Source Type: research
Laparoscopic Dissection of Lymph Node Station 16-Why and How?
CONCLUSIONS: While station 16 provides important prognostic information for risk stratification, a strategic and stepwise approach is needed for a safe sampling. This is accomplished by wide mobilization of the duodenum, implementation of thermal fusion to minimize chyle leak, and careful dissection below the left renal vein.PMID:38411760 | DOI:10.1245/s10434-024-15040-2 (Source: Ann Oncol)
Source: Ann Oncol - February 27, 2024 Category: Cancer & Oncology Authors: William Kawahara Eduardo A Vega Omid Salehi Sebastian Mellado Oscar Salirrosas Richard Freeman Elena Panettieri Claudius Conrad Source Type: research
Innovations in surgery for gallbladder cancer: A review of robotic surgery as a feasible and safe option
This study evaluates the efficacy and safety of robotic-assisted surgical techniques in the treatment of gallbladder cancer, comparing it with traditional open and laparoscopic methods. (Source: American Journal of Surgery)
Source: American Journal of Surgery - February 27, 2024 Category: Surgery Authors: Sebastian Mellado, Ariana M. Chirban, Emanuel Shapera, Belen Rivera, Elena Panettieri, Marcelo Vivanco, Claudius Conrad, Iswanto Sucandy, Eduardo A. Vega Tags: Review Article Source Type: research
Management of incidentally detected gallbladder polyps: a review of clinical scenarios using the 2022 SRU gallbladder polyp consensus guidelines
AbstractGallbladder (GB) polyps are a common incidental finding on sonography, but only a small fraction of polyps become GB cancer. The Society of Radiologists in Ultrasound (SRU) consensus committee recently performed an extensive literature review and published guidelines for GB polyp follow-up/management to provide clarity among the many heterogeneous recommendations that are available to clinicians. As these guidelines have become adopted into clinical practice, challenging clinical scenarios have arisen including GB polyps in primary sclerosing cholangitis (PSC), high risk geographic/genetic patient populations, shri...
Source: Abdominal Imaging - February 27, 2024 Category: Radiology Source Type: research
An unusual case series of synchronous primary malignancies: Carcinoma gallbladder with renal cell carcinoma, carcinoma gallbladder with carcinoma colon, carcinoma gallbladder with carcinoma breast
J Cancer Res Ther. 2023 Jan 1;19(Suppl 2):S958-S962. doi: 10.4103/jcrt.jcrt_976_22. Epub 2023 Apr 30.ABSTRACTSynchronous primary cancers are very rare. Due to their low incidence rate and insidious onset, they may be easily overlooked or misdiagnosed. In addition, there is currently no international consensus for their clinical diagnosis and treatment. Three exceedingly unusual synchronous primary malignancies, carcinoma gallbladder with renal cell carcinoma, carcinoma gallbladder with carcinoma colon, and carcinoma gallbladder with carcinoma breast, are presented here. Together with their clinical presentation, therapeuti...
Source: Cell Research - February 22, 2024 Category: Cytology Authors: Sashibhusan Dash Subrat K Samantara Krushna C Pani Manoranjan Ranjit Source Type: research
A Comprehensive narrative review of transcriptomics and epigenomics of gallbladder cancer
J Cancer Res Ther. 2023 Jan 1;19(Suppl 2):S499-S507. doi: 10.4103/jcrt.jcrt_1823_23. Epub 2024 Feb 21.ABSTRACTGallbladder cancer (GBC) is one of the quiet prevalent and aggressive biliary tract malignant neoplasms distinguished by significant cellular heterogeneity, metastatic activity, and a poor prognosis, with varied frequency worldwide. Most cases are detected incidentally while routine screening imaging or pathological investigation of cholecystectomy tissues and usually present with advanced disease. The surgical resection is usually done in the initial clinical stage having limited spread. Despite the surgical thera...
Source: Cell Research - February 22, 2024 Category: Cytology Authors: Pranay Tanwar Shilpi Minocha Ishaan Gupta Source Type: research
The anticancer activity of bile acids in drug discovery and development
Bile acids (BAs) constitute essential components of cholesterol metabolites that are synthesized in the liver, stored in the gallbladder, and excreted into the intestine through the biliary system. They play a crucial role in nutrient absorption, lipid and glucose regulation, and the maintenance of metabolic homeostasis. In additional, BAs have demonstrated the ability to attenuate disease progression such as diabetes, metabolic disorders, heart disease, and respiratory ailments. Intriguingly, recent research has offered exciting evidence to unveil their potential antitumor properties against various cancer cell types incl...
Source: Frontiers in Pharmacology - February 20, 2024 Category: Drugs & Pharmacology Source Type: research
Drug approach to treatment for obesity in adults: perspectives and considerations
Rev Esp Enferm Dig. 2024 Feb 12;116. doi: 10.17235/reed.2024.10206/2023. Online ahead of print.ABSTRACTObesity is considered a chronic disease and a serious public-health issue in Spain, as well as in many other countries, primarily because of it being a significant risk factor for multiple chronic conditions, including diabetes mellitus type 2, cardiovascular disease, respiratory disease, metabolic dysfunction-associated fatty liver disease, gastrointestinal conditions (gastroesophageal reflux, diverticulosis), musculoskeletal difficulties, infertility, and even development of some malignancies such as postmenopausal brea...
Source: Revista Espanola de Enfermedades Digestivas - February 12, 2024 Category: Gastroenterology Authors: Javier Escalada Source Type: research
