MKSAP: 40-year-old man with a new skin rash of 10 days ’ duration
Test your medicine knowledge with the  MKSAP challenge, in partnership with the American College of Physicians. A 40-year-old man is evaluated for a new skin rash of 10 days’ duration. The rash appeared abruptly and is not tender or pruritic. The patient has poorly controlled type 2 diabetes mellitus. His current medications include metformin and glyburide. Family […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 9, 2019 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > < /span > Tags: Conditions Dermatology Diabetes Endocrinology Source Type: blogs
Video of Investor Jim Mellon Presenting at Abundance 360 Summit 2019
Jim Mellon's Juvenescence venture is at present one of the few major venture organizations focused on approaches to treat aging as a medical condition. Mellon and his colleagues outlined their take on the field in a 2017 book, also called Juvenescence. We are fortunate in that he is among the first few high net worth individuals to both agree with the SENS philosophy of damage repair, and then, much more importantly, follow through in action as well as word. He is not just seeing a massive market opportunity in treating aging, though that is certainly there, but is doing this because he wishes to achieve the goal of radica...
Source: Fight Aging! - March 4, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Ask D'Mine: Diabetes Medicines Mailbag
Our weekly DiabetesMine advice column answers readers ' logistical questions about taking metformin, Toujeo and other diabetes medications. (Source: Diabetes Mine)
Source: Diabetes Mine - February 23, 2019 Category: Endocrinology Authors: Wil Dubois Source Type: blogs
Stack the odds in favor of reversing type 2 diabetes
A carb-restricted diet is only a START in stacking the odds in favor of fully reversing, or at least minimizing, type 2 diabetes.
You must address the several factors in health that allow insulin to do its job, i.e., restore INSULIN RESISTANCE. This is what we do in the Wheat Belly Total Heath and now Undoctored lifestyles.
Transcript:
Let’s talk about how you can stack the odds in favor of a full reversal of Type II diabetes. You know what, about 90% of people, who have Type II diabetes — even if they’ve had it for 5 years, 10 years, or longer, can become confidently non-diabetic, or at the very least,...
Source: Wheat Belly Blog - February 10, 2019 Category: Cardiology Authors: Dr. Davis Tags: News & Updates blood sugar diabetes gluten-free grain-free grains low-carb undoctored wheat belly Wheat Belly Total Health Source Type: blogs
Fight Aging! Newsletter, February 11th 2019
We report that the bone marrow stromal cell senescence is driven by p16INK4a expression. The p16INK4a-expressing senescent stromal cells then feedback to promote AML blast survival and proliferation via the SASP.
Importantly, selective elimination of p16INK4a-positive senescent bone marrow stromal cells in vivo improved the survival of mice with leukemia. Next, we find that the leukemia-driven senescent tumor microenvironment is caused by AML induced NOX2-derived superoxide. Finally, using the p16-3MR mouse model we show that by targeting NOX2 we reduced bone marrow stromal cell senescence and consequently reduced A...
Source: Fight Aging! - February 10, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Thoughts on the Longevity Therapeutics Conference, January 2019
I attended the small Longevity Therapeutics conference in San Francisco last week, there to talk a little about the work taking place at Repair Biotechnologies. This was another first conference of a forthcoming series, but, unlike most of the prior conferences in our community, this was organized by Hanson-Wade, a company that specializes in hosting conferences. The company finds areas of growing interest in business and science, sets up conferences, and tries to make a business out of that process. It is a sign of growth that companies of this nature are arriving in our community to launch conferences relating to the dev...
Source: Fight Aging! - February 4, 2019 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
ZERO tolerance for hypoglycemia
As more and more type 2 diabetics discover the Wheat Belly and other low-carb lifestyles, they are also discovering how rapidly and easily blood sugars drop.
As diabetics become less diabetic–a process that can occur VERY quickly, often within 24 hours of removing all wheat/grains from their diet–but they are taking insulin or certain diabetes drugs, there is potential for hypoglycemia or low blood sugar. Low blood sugar from diabetes drugs can be dangerous and should be avoided at all costs. (Imagine if a non-diabetic started administering insulin or blood sugar-reducing drugs–it would result in life-threate...
Source: Wheat Belly Blog - December 23, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates blood sugar diabetes undoctored wheat belly Source Type: blogs
Tammy Talks About Her Wheat Belly Success
I previously shared Tammy’s Wheat Belly success story that illustrates just how far you can take back health and reverse numerous chronic health conditions. Besides losing over 70 pounds in weight, she also:
Reversed type 2 diabetes, reducing HbA1c from the diabetic range of 8.4% to 4.9%—an ideal level.
Reversed hypertension
Reversed gastroesophageal reflux
Reversed irritable bowel syndrome
Reversed rheumatoid arthritis
She has also been able to discontinue a list of toxic medications, including metformin, Prilosec, and Remicade. And, as you can readily see, turned the clock back 20 years in appearance...
Source: Wheat Belly Blog - December 3, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates autoimmune blood sugar diabetes gastroesphageal gerd Gliadin gluten gluten-free grain-free grains high blood pressure hypertension Inflammation irritable bowel its Weight Loss wheat belly Source Type: blogs
Fight Aging! Newsletter, November 26th 2018
This study is the culmination of a decade of research that has repeatedly demonstrated that this vaccine can effectively and safely target in animal models what we think may cause Alzheimer's disease. I believe we're getting close to testing this therapy in people."
Although earlier research established that antibodies significantly reduce amyloid buildup in the brain, researchers needed to find a safe way to introduce them into the body. A vaccine developed elsewhere showed promise in the early 2000s, but when tested in humans, it caused brain swelling in some patients. The new idea was to start with DNA coding for...
Source: Fight Aging! - November 25, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Can Money Buy You Longevity And Health?
Better treatment options, dietary conditions and (perhaps) less stress could make the life of the rich also healthier. However, when it comes to longevity and aging, do they really have better chances? Can the upper 0.1 percent secure their health for long decades or even reverse the process of growing old? Could society somehow also benefit from the quest of the richest for longevity?
Are health and longevity on the shopping list?
You can have an awful lot of things with money. For a starter, you can buy ice cream or Nutella, which are synonymous to self-love, so the Beatles was only partly right in singing that you canâ€...
Source: The Medical Futurist - November 22, 2018 Category: Information Technology Authors: nora Tags: Bioethics Cyborgization Future of Medicine Medical Professionals Patients Policy Makers age aging aging research blood eternal life genetics immortality Innovation life sciences longevity silicon valley stem cell Source Type: blogs
Future Directions for the Senescence Field
Today's open access paper is, I think, chiefly interesting for the later section in which the authors ponder future directions for the treatment of aging via means of destroying or manipulating the activity of senescent cells. The accumulation of senescent cells is one of the root causes of aging. The creation of senescent cells happens constantly in the undamaged and fully functional tissues of young people, a tiny fraction of these senescent cells manage to evade destruction and linger to cause issues, and given enough time that fraction will grow large enough to kill you. Cellular senescence isn't the only harmful cause...
Source: Fight Aging! - November 19, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, November 19th 2018
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more.
This content is...
Source: Fight Aging! - November 18, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Milken Institute's Longevity Innovators Interviews
The Milken Institute has published a set of interviews with a variety of scientists and non-scientists on topics of human longevity. A few these are of interest to those of who would like to see a fast path to rejuvenation therapies unfold in the years ahead. Some of the others illustrate a point I made last week, which is that while all that really needs to happen in this field is for the biotechnologies of rejuvenation to be developed, and as quickly and directly as possible, there are those who feel that the sociological aspects of human longevity must be talked to death in advance. Thus broader advocacy initiatives ten...
Source: Fight Aging! - November 16, 2018 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
Fight Aging! Newsletter, November 5th 2018
In conclusion, weight cycling significantly increased life-span relative to remaining with obesity and had a similar benefit to sustained modest weight loss.
Support for Oxidized Cholesterol as a Primary Cause of Atherosclerosis
https://www.fightaging.org/archives/2018/11/support-for-oxidized-cholesterol-as-a-primary-cause-of-atherosclerosis/
In the paper I'll point out today, the authors provide evidence in support of the concept that it is specifically oxidized cholesterol that is the primary cause of atherosclerosis rather than the condition resulting from too much cholesterol in general. In atherosc...
Source: Fight Aging! - November 4, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Combinations of Approaches to Slow Aging are Not Well Explored
Scores of distinct ways to modestly slow aging in short-lived species have been demonstrated in the laboratory over the past decades. Many are redundant, influencing the same underlying mechanism, but others produce effects on the operation of cellular metabolism that are different enough to be synergistic. Unfortunately the research community does very little work on combined therapies; this true for all fields of medicine, not just aging. This is perhaps partially the culture of science, and partially the consequence of heavy handed regulation and intellectual property law. The financial incentives at all level of resear...
Source: Fight Aging! - October 31, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
