The appropriateness of the use of statins for the secondary and primary prevention of atherosclerotic cardiovascular disease: a cross-sectional study from Jordan
CONCLUSIONS: The use of statins was not in concordance with the guidelines. Many of the patients surveyed were undertreated and adequate follow-up to identify the extent of patients' compliance and response was missing.PMID:37401284 | DOI:10.26355/eurrev_202306_32785 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - July 4, 2023 Category: Drugs & Pharmacology Authors: L Gharaibeh S Al Zoubi H Sartawi D Ayyad M Al-Hawamdeh R Alrashdan Source Type: research

Association between Statins Types with Incidence of Liver Cancer: An Updated Meta-analysis
Conclusion: Both lipophilic and hydrophilic statins contribute to the prevention of liver cancer. Moreover, the efficacy was influenced by the region and the specific type of statins used.PMID:37393552 | DOI:10.2174/0929867330666230701000400 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - July 2, 2023 Category: Chemistry Authors: Xingfen Zhang Dandi Lou Rongrong Fu Feng Wu Dingcheng Zheng Xueqiang Ma Source Type: research

Association between Statins Types with Incidence of Liver Cancer: An Updated Meta-analysis
Conclusion: Both lipophilic and hydrophilic statins contribute to the prevention of liver cancer. Moreover, the efficacy was influenced by the region and the specific type of statins used.PMID:37393552 | DOI:10.2174/0929867330666230701000400 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - July 2, 2023 Category: Chemistry Authors: Xingfen Zhang Dandi Lou Rongrong Fu Feng Wu Dingcheng Zheng Xueqiang Ma Source Type: research

Association between Statins Types with Incidence of Liver Cancer: An Updated Meta-analysis
Conclusion: Both lipophilic and hydrophilic statins contribute to the prevention of liver cancer. Moreover, the efficacy was influenced by the region and the specific type of statins used.PMID:37393552 | DOI:10.2174/0929867330666230701000400 (Source: Current Medicinal Chemistry)
Source: Current Medicinal Chemistry - July 2, 2023 Category: Chemistry Authors: Xingfen Zhang Dandi Lou Rongrong Fu Feng Wu Dingcheng Zheng Xueqiang Ma Source Type: research

Associations between SLCO1B1, APOE and  CYP2C9 and lipid-lowering efficacy and pharmacokinetics of fluvastatin: a meta-analysis
Pharmacogenomics, Ahead of Print. (Source: Future Medicine: Pharmacogenomics)
Source: Future Medicine: Pharmacogenomics - June 15, 2023 Category: Genetics & Stem Cells Authors: Zi Hao Zhang Li Chao Yue Sun Hong Yan Gu De Chun Jiang Zhan Miao Yi Source Type: research

MYD88 and Proinflammatory Chemokines in Aortic Atheromatosis: Exploring Novel Statin Effects
In conclusion, statin therapy can halt proatherogenic inflammation in hyperlipidemic animals. Rosuvastatin may be more effective in downregulating MYD88 in atherosclerotic thoracic aortas.PMID:37298199 | PMC:PMC10252457 | DOI:10.3390/ijms24119248 (Source: Atherosclerosis)
Source: Atherosclerosis - June 10, 2023 Category: Cardiology Authors: Konstantinos S Mylonas Michail Peroulis Dimitrios Schizas Alkistis Kapelouzou Source Type: research

MYD88 and Proinflammatory Chemokines in Aortic Atheromatosis: Exploring Novel Statin Effects
In conclusion, statin therapy can halt proatherogenic inflammation in hyperlipidemic animals. Rosuvastatin may be more effective in downregulating MYD88 in atherosclerotic thoracic aortas.PMID:37298199 | DOI:10.3390/ijms24119248 (Source: Atherosclerosis)
Source: Atherosclerosis - June 10, 2023 Category: Cardiology Authors: Konstantinos S Mylonas Michail Peroulis Dimitrios Schizas Alkistis Kapelouzou Source Type: research

Statins exert anti-growth effects by suppressing YAP/TAZ expressions via JNK signal activation and eliminate the immune suppression by downregulating PD-L1 expression in pancreatic cancer
In conclusion, Statins display two distinct anti-cancer effects (direct anti-growth effect and elimination of immune suppression by downregulating PD-L1 expression) by targeting YAP/TAZ expression.PMID:37293171 | PMC:PMC10244110 (Source: Cell Research)
Source: Cell Research - June 9, 2023 Category: Cytology Authors: Norio Uemura Hiromitsu Hayashi Zhao Liu Kazuki Matsumura Yoko Ogata Noriko Yasuda Hiroki Sato Yuta Shiraishi Tatsunori Miyata Shigeki Nakagawa Kosuke Mima Hidetoshi Nitta Hideo Baba Source Type: research

Statins exert anti-growth effects by suppressing YAP/TAZ expressions via JNK signal activation and eliminate the immune suppression by downregulating PD-L1 expression in pancreatic cancer
In conclusion, Statins display two distinct anti-cancer effects (direct anti-growth effect and elimination of immune suppression by downregulating PD-L1 expression) by targeting YAP/TAZ expression.PMID:37293171 | PMC:PMC10244110 (Source: Cell Research)
Source: Cell Research - June 9, 2023 Category: Cytology Authors: Norio Uemura Hiromitsu Hayashi Zhao Liu Kazuki Matsumura Yoko Ogata Noriko Yasuda Hiroki Sato Yuta Shiraishi Tatsunori Miyata Shigeki Nakagawa Kosuke Mima Hidetoshi Nitta Hideo Baba Source Type: research

Retraction Note: Fluvastatin-Loaded Emulsomes Exhibit Improved Cytotoxic and Apoptosis in Prostate Cancer Cells
AAPS PharmSciTech. 2023 Jun 2;24(5):128. doi: 10.1208/s12249-023-02591-y.NO ABSTRACTPMID:37266798 | DOI:10.1208/s12249-023-02591-y (Source: AAPS PharmSciTech)
Source: AAPS PharmSciTech - June 2, 2023 Category: Drugs & Pharmacology Authors: Nabil A Alhakamy Shaimaa M Badr-Eldin Hibah M Aldawsari Anas Alfarsi Thikryat Neamatallah Solomon Z Okbazghi Usama A Fahmy Osama A A Ahmad Basma G Eid Wael Ali Mahdi Adel F Alghaith Sultan Alshehri Shadab Md Source Type: research