Statins exert anti-growth effects by suppressing YAP/TAZ expressions via JNK signal activation and eliminate the immune suppression by downregulating PD-L1 expression in pancreatic cancer

In conclusion, Statins display two distinct anti-cancer effects (direct anti-growth effect and elimination of immune suppression by downregulating PD-L1 expression) by targeting YAP/TAZ expression.PMID:37293171 | PMC:PMC10244110

Source: Cell Research - June 9, 2023 Category: Cytology Authors: Norio Uemura Hiromitsu Hayashi Zhao Liu Kazuki Matsumura Yoko Ogata Noriko Yasuda Hiroki Sato Yuta Shiraishi Tatsunori Miyata Shigeki Nakagawa Kosuke Mima Hidetoshi Nitta Hideo Baba Source Type: research