Intestinal Parasitic Infections in People Referring to the Central Laboratory of Meshkin Shahr County, Ardabil Province, Iran
CONCLUSION: In- spite of betterment of the health condition in Iran and reduction of parasitic infection, intestinal parasitic infections are still a considerable public health issue in some parts of Iran.PMID:38654952 | PMC:PMC11033542 | DOI:10.18502/ijpa.v19i1.15217 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - April 24, 2024 Category: Parasitology Authors: Pooria Asadi Zabihollah Zarei Mehdi Mohebali Zahra Alizadeh Faezeh Najafi Shahrokh Izadi Zahra Heidari Source Type: research

Evaluation of Th1/Th2, regulatory cytokines and transcriptional factor FoxP3 in sheep immunized with a partially protective and non-protective vaccine and challenged with Fasciola hepatica
AbstractGene expression for Th1/Th2 cytokines (IL-4 and IFN- ɣ), regulatory cytokines (TGF-β and IL-10) and the transcriptional factor FoxP3 was analyzed in the liver and hepatic lymph nodes (HLN) from sheep immunized with partially protective and non-protective vaccine candidates and challenged withFasciola hepatica. FoxP3 T cells were also evaluated by immunohistochemistry (IHQ). The most remarkable difference between the partially protected vaccinated (V1) group and the non-protected vaccinated (V2) group was a more severe expansion of FoxP3 T cells recorded by IHQ in both the liver and HLN of the V2 group as compared...
Source: Veterinary Research - April 24, 2024 Category: Veterinary Research Source Type: research

In vitro assessment of the anthelmintic activity of copper oxide and zinc oxide nanoparticles on egg and adult stages of Fasciola hepatica: evidence on oxidative stress biomarkers, and DNA damage
Fasciolosis is of significant economic and public health importance worldwide. The lack of a successful vaccine and emerging resistance in flukes to the drug of choice, triclabendazole, has initiated the searc... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - April 4, 2024 Category: Veterinary Research Authors: Amirhassan Ravvaz, Farnaz Malekifard and Bijan Esmaeilnejad Tags: Research Source Type: research

Citizens can help to map putative transmission sites for snail-borne diseases
Conclusions and recommendationsOur results demonstrate the potential of citizen science to map putative schistosomiasis transmission sites. We therefore argue that this inclusive, powerful and cost-effective approach can be more sustainable than top-down monitoring and intervention campaigns. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 4, 2024 Category: Tropical Medicine Authors: Julius Tumusiime Source Type: research

GSE254115 Examining the non-coding RNA profiles of macrophages from mice infected with Fasciola hepatica reveals a co-operation between host and parasite to reduce pro-inflammatory responses and promote tissue repair
Contributors : Dayna Sais ; Sheila Donnelley ; Nham TranSeries Type : Expression profiling by high throughput sequencing ; Non-coding RNA profiling by high throughput sequencingOrganism : Mus musculusParasitic worms (helminths) ensure their survival to establish chronic infection within mammalian hosts by strategically regulating their host ’s immune responses. Deciphering the mechanisms behind this immune modulation will inform the development of novel strategies for infection control. It is now understood that the co-ordinated control of gene expression by non-coding RNAs (ncRNA) underpins the activation and regulat...
Source: GEO: Gene Expression Omnibus - April 3, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Non-coding RNA profiling by high throughput sequencing Mus musculus Source Type: research

New benzimidazole derivative compounds with in vitro fasciolicidal properties
Control of the zoonotic food-borne parasite Fasciola hepatica remains a major challenge in humans and livestock. It is estimated that annual economic losses due to fasciolosis can reach US$3.2 billion in agricult... (Source: Parasites and Vectors)
Source: Parasites and Vectors - April 3, 2024 Category: Microbiology Authors: Elora Valderas-Garc ía, Verónica Castilla-Gómez de Agüero, Laura González del Palacio, Giulio Galli, Nerea Escala, Marta Ruiz-Somacarrera, Marta González-Warleta, Esther del Olmo, Rafael Balaña-Fouce and María Martínez-Valladares Tags: Research Source Type: research

Blood parameters and parasite burden in cattle with chronic fascioliasis
The objective of this work was to gain insight in these aspects. Cattle from Mendoza province, Argentina, were inspected at a farm and at the abattoir determining the presence or absence of Fasciola hepatica. Each animal was sampled for blood and feces and in the slaughterhouse the livers were inspected. Hematology and blood chemistry parameters were determined, feces were examined for F. hepatica eggs by a quantitative sedimentation technique and livers were thoroughly inspected to determine the number of flukes. Infected cattle presented a mild burden of liver flukes per animal, strongly correlated (r=0.72) to the number...
Source: Acta Tropica - March 29, 2024 Category: Infectious Diseases Authors: Gisela Neira Roberto Meray Sierra Franco Cremaschi Noelia Sohaefer Mariana Gonz ález Dayana Godoy Silvana Scarcella Source Type: research

Blood parameters and parasite burden in cattle with chronic fascioliasis
The objective of this work was to gain insight in these aspects. Cattle from Mendoza province, Argentina, were inspected at a farm and at the abattoir determining the presence or absence of Fasciola hepatica. Each animal was sampled for blood and feces and in the slaughterhouse the livers were inspected. Hematology and blood chemistry parameters were determined, feces were examined for F. hepatica eggs by a quantitative sedimentation technique and livers were thoroughly inspected to determine the number of flukes. Infected cattle presented a mild burden of liver flukes per animal, strongly correlated (r=0.72) to the number...
Source: Acta Tropica - March 29, 2024 Category: Infectious Diseases Authors: Gisela Neira Roberto Meray Sierra Franco Cremaschi Noelia Sohaefer Mariana Gonz ález Dayana Godoy Silvana Scarcella Source Type: research

Correction: Fasciola hepatica soluble antigens (FhAg) induce ovine PMN innate immune reactions and NET formation in vitro and in vivo
(Source: Veterinary Research)
Source: Veterinary Research - March 26, 2024 Category: Veterinary Research Source Type: research

Correlation between the Fasciola hepatica infection rate (number of parasites in the liver parenchyma) and the antibody titration, detected by ELISA assay
This study aimed to demonstrate the existence of a possible correlation between the level of liver fluke infection in cattle caused byFasciola hepatica and the titers of anti-parasite antibodies in the blood. 113 blood samples were taken from non-dewormed pasture cattle in the communal slaughterhouse of the Jijel city in order to determine the serological titration of anti-fluke antibodies by the ELISA method. After slaughtering the animals studied, a count of parasites present in the inspected livers was carried out in order to assess the level of parasitic infection. The prevalence of bovine fasciolosis (due toFasciola h...
Source: Journal of Parasitic Diseases - March 11, 2024 Category: Parasitology Source Type: research

Gastropod invasions in anthropogenically impacted impoundments in South Africa: tracing their origins and exploring field evidence of parasite spillback and amplification
Int J Parasitol. 2024 Mar 5:S0020-7519(24)00050-X. doi: 10.1016/j.ijpara.2024.02.004. Online ahead of print.ABSTRACTInvasive snails are associated with ecological problems in freshwater bodies worldwide. However, their impact on the transmission of digenean infections remain underreported. In the present study, 1708 specimens representing four snail species were sampled from four impoundments in the Limpopo River system in South Africa. Gyraulus chinensis (Planorbidae), Physella acuta (Physidae) and Pseudosuccinea columella (Lymnaeidae), which are invasive, were found in all the sampling sites. In contrast, the native lymn...
Source: International Journal for Parasitology - March 7, 2024 Category: Parasitology Authors: James Omondi Outa Parthi Bhika Annemari è Avenant-Oldewage Source Type: research

Gastropod invasions in anthropogenically impacted impoundments in South Africa: tracing their origins and exploring field evidence of parasite spillback and amplification
Int J Parasitol. 2024 Mar 5:S0020-7519(24)00050-X. doi: 10.1016/j.ijpara.2024.02.004. Online ahead of print.ABSTRACTInvasive snails are associated with ecological problems in freshwater bodies worldwide. However, their impact on the transmission of digenean infections remain underreported. In the present study, 1708 specimens representing four snail species were sampled from four impoundments in the Limpopo River system in South Africa. Gyraulus chinensis (Planorbidae), Physella acuta (Physidae) and Pseudosuccinea columella (Lymnaeidae), which are invasive, were found in all the sampling sites. In contrast, the native lymn...
Source: International Journal for Parasitology - March 7, 2024 Category: Parasitology Authors: James Omondi Outa Parthi Bhika Annemari è Avenant-Oldewage Source Type: research

Letter to the Editor: A Case Report of Biliary Obstruction Caused by Live Fasciola hepatica
Surgical Infections, Ahead of Print. (Source: Surgical Infections)
Source: Surgical Infections - March 6, 2024 Category: Surgery Authors: Hui Wei Jianhao Huang Xiaoli Yang Kai He Source Type: research

Laboratory Assessment of Molluscicidal Activities of Cannabis sativa, Acacia nilotica, and Tinospora cordifolia Against Snail Host of Fasciola spp.
Vector-Borne and Zoonotic Diseases, Ahead of Print. (Source: Vector-Borne and Zoonotic Diseases)
Source: Vector-Borne and Zoonotic Diseases - February 16, 2024 Category: Infectious Diseases Authors: Nilay Vishal Singh Arundhati Singh Vinay Kumar Singh Source Type: research