For Ocular Melanoma Mets to Liver, Fotemustine DisappointsFor Ocular Melanoma Mets to Liver, Fotemustine Disappoints
For patients with uveal melanoma (UM) metastases in the liver, response rates and progression-free survival are only slightly better if fotemustine is given through the hepatic artery rather then intravenously, new data show. Reuters Health Information (Source: Medscape Ophthalmology Headlines)
Source: Medscape Ophthalmology Headlines - March 27, 2014 Category: Opthalmology Tags: Hematology-Oncology News Source Type: news
Early detection of childhood eye cancer doesn't always improve survival, prevent eye loss
For the most common form of childhood eye cancer, unilateral retinoblastoma, shortening the time from the first appearance of symptoms to diagnosis of disease has no bearing on survival or stage of the disease, according to a study by researchers at Columbia University Mailman School of Public Health in partnership with the Hospital Infantil de Mexico. The results appear online in the journal Cancer Epidemiology, Biomarkers & Prevention. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 20, 2014 Category: Consumer Health News Tags: Eye Health / Blindness Source Type: news
Early detection of childhood eye cancer doesn't always improve survival, prevent eye loss
(Columbia University's Mailman School of Public Health) For the most common form of childhood eye cancer, unilateral retinoblastoma, shortening the time from the first appearance of symptoms to diagnosis of disease has no bearing on survival or stage of the disease, according to a study by researchers at Columbia University Mailman School of Public Health in partnership with the Hospital Infantil de Mexico. The results appear online in the journal Cancer Epidemiology, Biomarkers & Prevention. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - March 18, 2014 Category: Cancer & Oncology Source Type: news
Pancreatic cancer cell growth promoted by retinoblastoma dysfunction
Indiana University cancer researchers have discovered that a protein that normally suppresses tumors actually promotes the growth and spread of pancreatic cancer.Murray Korc, M.D., the Myles Brand Professor of Cancer Research at the Indiana University School of Medicine and a researcher at the Indiana University Melvin and Bren Simon Cancer Center, and colleagues have shown that the retinoblastoma protein, a tumor suppressor, often malfunctions in pancreatic cancer. That dysfunction enables an inhibitory protein to promote pancreatic cancer growth. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 20, 2013 Category: Consumer Health News Tags: Pancreatic Cancer Source Type: news
Doctors Eye Cancer Risk in Uterine Procedure
An increasingly popular method of removing common uterine growths is coming under assault by some doctors worried about the risk of spreading a potentially deadly cancer. (Source: WSJ.com: Health)
Source: WSJ.com: Health - December 18, 2013 Category: Pharmaceuticals Tags: PAID Source Type: news
IU cancer researchers: Retinoblastoma dysfunction promotes pancreatic cancer cell growth
(Indiana University) Indiana University cancer researchers have discovered that a protein that normally suppresses tumors actually promotes the growth and spread of pancreatic cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 16, 2013 Category: Global & Universal Source Type: news
Researchers unravel important role of Rb tumor suppressor in aggressive form of breast cancer
The retinoblastoma (Rb) protein plays a critical role in suppressing the multi-step process of cell migration through the bloodstream, lymphovascular invasion and the metastasis of an aggressive type of breast cancer to the lung, researchers at the University of Cincinnati (UC) Cancer Institute, the Cincinnati Cancer Center (CCC) and the UC Brain Tumor Center have found.The findings of Rb's role at multiple points in the disease process point to a potential new therapeutic target in patients with the most aggressive subset of breast cancer, known as basal-like breast carcinomas. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 6, 2013 Category: Consumer Health News Tags: Breast Cancer Source Type: news
UC researchers unravel important role of Rb tumor suppressor in aggressive form of breast cancer
(University of Cincinnati Academic Health Center) The retinoblastoma protein plays a critical role in suppressing the multi-step process of cell migration through the bloodstream, lymphovascular invasion and the metastasis of an aggressive type of breast cancer to the lung, researchers at the University of Cincinnati (UC) Cancer Institute, the Cincinnati Cancer Center and the UC Brain Tumor Center have found. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 4, 2013 Category: Cancer & Oncology Source Type: news
Parents can check their kids for retinoblastoma using digital photography
Can parents use digital cameras and smart phones to potentially screen their children for the most common form of pediatric eye cancer? Baylor University and Harvard Medical School researchers believe so. In their study, published online this week in PLOS One, the researchers discovered, through the use of amateur digital photography, evidence of leukocoria or "white eye," the cardinal symptom of retinoblastoma, which can be seen in photographs during the earliest stages of the disease... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 8, 2013 Category: Consumer Health News Tags: Eye Health / Blindness Source Type: news
How Pictures Of Infant Boy's Eyes Helped Diagnose Cancer
A research chemist applied his analytical smarts to his son's eye cancer. By analyzing family photos starting with some taken just a few days after birth, the dad found that signs of retinoblastoma, a rare eye cancer, could be detected quite early.» E-Mail This » Add to Del.icio.us (Source: NPR Health and Science)
Source: NPR Health and Science - November 6, 2013 Category: Consumer Health News Source Type: news
Researchers help make pediatric eye cancer easier to detect
(Massachusetts Eye and Ear Infirmary) Can parents use digital cameras and smart phones to potentially screen their children for the most common form of pediatric eye cancer? Baylor University and Harvard Medical School researchers believe so. Findings in PLOS One. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - November 6, 2013 Category: Global & Universal Source Type: news
JCI early table of contents for Nov. 1, 2013
(Journal of Clinical Investigation) This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Nov. 1, 2013 in the JCI: "Liver tropism is key for B cell deletion immunotherapy," "Dysfunctional chemokine receptor promotes candidiasis," "Retinoblastoma protein prevents enteric nervous system defects and intestinal pseudo-obstruction," "Transmembrane protein ESDN promotes endothelial VEGF signaling and regulates angiogenesis," "Apelin is a positive regulator of ACE2 in failing hearts," and more. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 1, 2013 Category: Global & Universal Source Type: news
Surgical Management of Posterior Uveal MelanomaSurgical Management of Posterior Uveal Melanoma
Uveal melanoma is the most common primary malignancy of the eye in adults and affects approximately 4 people per million in the US each year. Find out how globe-salvaging treatment and more are improving outcomes. Expert Review of Ophthalmology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 24, 2013 Category: Consumer Health News Tags: Ophthalmology Journal Article Source Type: news
Castle Biosciences launches tissue repository for eye cancer patients
Castle Biosciences Inc. has announced the availability of a tumor tissue repository for patients whose tumors are being tested with the Company's gene test for uveal, or ocular, melanoma. Patients will now have the option of storing an additional sample of their tumor free of charge for up to five years, and will be able to access it to take advantage of future developments in the disease. Castle Biosciences would provide the samples to third parties only with permission of the patient for legitimate research, treatment guidance or diagnostic purposes... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 2, 2013 Category: Consumer Health News Tags: Eye Health / Blindness Source Type: news
An unusual route to saving a child’s eye
Poppy Biagini (left) and Liam Klagges (right), each with the white glow of retinoblastoma in one eye. (Courtesy Dana Biagini and Amy Klagges)
All Poppy Biagini’s family knew was that something was off about her right eye. Liam Klagges’ family’s first sign that something was wrong was that his eyes didn’t always track properly, and that his left eyelid hung a little lower than his right.
Both children, it turns out, had a tumor called a retinoblastoma. Usually diagnosed in children younger than 5, it’s rare—only about 300 children in the United States are diagnosed with it every year—but grows...
Source: Thrive, Children's Hospital Boston - August 2, 2013 Category: Pediatrics Authors: Tom Ulrich Tags: All posts Cancer Allison O'Neill Ankoor Shah Dana-Farber/Boston Children's Cancer and Blood Disorders Center Darren Orbach Deborah VanderVeen intra-arterial (IA) MD our patients' stories PhD retinoblastoma Solid Tumors Center at Da Source Type: news
