Spread of deadly eye cancer halted in cells and animals
(Johns Hopkins Medicine) By comparing genetic sequences in the eye tumors of children whose cancers spread with tumors that didn't spread, Johns Hopkins Medicine researchers report new evidence that a domino effect in cells is responsible for the cancer spreading. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 12, 2018 Category: International Medicine & Public Health Source Type: news

Toddler loses her eye to a rare form of cancer after her mother noticed she couldn't see
Alice Taylor, from Poole, Dorset, was diagnosed with the aggressive eye cancer retinoblastoma in May last year when she was just two years old. She had been going blind in her left eye for months. (Source: the Mail online | Health)
Source: the Mail online | Health - October 11, 2018 Category: Consumer Health News Source Type: news

CHLA team identifies developmental stage for no. 1 eye tumor in children
(Children's Hospital Los Angeles) Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door for future interventions in retinoblastoma (RB), a tumor of the retina that affects children under five years of age. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 14, 2018 Category: International Medicine & Public Health Source Type: news

Eye cancer signs: Watch out for this symptom on the coloured part of your eye
EYE CANCER is not a common type of cancer but noticing certain signs as early as possible will help with your outlook. One of the symptoms to watch out for will appear on the coloured part of the eye, otherwise known as the iris. (Source: Daily Express - Health)
Source: Daily Express - Health - September 7, 2018 Category: Consumer Health News Source Type: news

Scientists identify weak point in deadly eye melanoma
(Washington University School of Medicine) A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - September 5, 2018 Category: Cancer & Oncology Source Type: news

Targeting nucleotide exchange to inhibit constitutively active G protein {alpha} subunits in cancer cells
Constitutively active G protein α subunits cause cancer, cholera, Sturge-Weber syndrome, and other disorders. Therapeutic intervention by targeted inhibition of constitutively active Gα subunits in these disorders has yet to be achieved. We found that constitutively active Gαq in uveal melanoma (UM) cells was inhibited by the cyclic depsipeptide FR900359 (FR). FR allosterically inhibited guanosine diphosphate–for–guanosine triphosphate (GDP/GTP) exchange to trap constitutively active Gαq in inactive, GDP-bound Gαβ heterotrimers. Allosteric inhibition of other Gα subunits...
Source: Signal Transduction Knowledge Environment - September 4, 2018 Category: Science Authors: Onken, M. D., Makepeace, C. M., Kaltenbronn, K. M., Kanai, S. M., Todd, T. D., Wang, S., Broekelmann, T. J., Rao, P. K., Cooper, J. A., Blumer, K. J. Tags: STKE Research Articles Source Type: news

Two-year-old boy battling rare cancer risks blindness as painful mass grows over his eye
Muhammad Junaid, from a small village in Mirpur Khas, Pakistan, suffers from Retinoblastoma - a type of carcinoma that usually affects children under the age of five. (Source: the Mail online | Health)
Source: the Mail online | Health - August 16, 2018 Category: Consumer Health News Source Type: news

Ocular oncologist Renelle Lim on the importance of regular eye exams
The Yale Medicine ophthalmologist says eye cancer treatments work best when the cancer is caught early. (Source: Yale Science and Health News)
Source: Yale Science and Health News - July 25, 2018 Category: Universities & Medical Training Source Type: news

Eye Cancer Intraocular Uveal Melanoma Treatment
Eye Cancer: Intraocular (Uveal) Melanoma Treatment (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - July 20, 2018 Category: General Medicine Source Type: news

International conference brings together world leaders in eye cancer
(Champalimaud Centre for the Unknown) The world's leading ocular oncology scientists and clinicians meet to discuss the latest research and treatment developments in eye cancer. The Ocular Oncogenesis and Oncology Conference (OOO) is held by the Association for Research in Vision and Ophthalmology (ARV0) in partnership with the Champalimaud Foundation, July 18-21 at the Champalimaud Centre in Lisbon, Portugal. The conference features international experts from ophthalmic and cancer centers from around the world, including the Americas, Asia and Europe. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 12, 2018 Category: Cancer & Oncology Source Type: news

Ocular Melanoma (Intraocular Melanoma or Uveal Melanoma)
Title: Ocular Melanoma (Intraocular Melanoma or Uveal Melanoma)Category: Diseases and ConditionsCreated: 5/8/2018 12:00:00 AMLast Editorial Review: 6/19/2018 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - June 19, 2018 Category: Cancer & Oncology Source Type: news

Mayo Clinic Q and A: Melanoma can begin in the eye
DEAR MAYO CLINIC: Is it true that melanoma can develop in the eyes? If so, how common is it? How is it treated? ANSWER:?Melanoma can begin in the eye ? a condition called intraocular melanoma. Treatment for intraocular melanoma used to primarily involve removing the affected eye. Now, however, radiation therapy often can be used [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 19, 2018 Category: Databases & Libraries Source Type: news

Uveal Melanoma: Better Survival With Liver-Directed Therapy Uveal Melanoma: Better Survival With Liver-Directed Therapy
Treatment for liver metastases in uveal cancer has changed over 50 years. At ASCO, one study charted the survival benefits seen with newer localized therapies; the other showed benefits of radioembolization.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 12, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Sidney Kimmel Cancer Center scientists to present at ASCO Annual Meeting
(Thomas Jefferson University) Scientists from the Sidney Kimmel Cancer Center (SKCC) at Jefferson Health will be presenting research and leading discussions on various topics, including metastatic uveal melanoma, genetic counseling in men, immunotherapy in early stage lung cancer and solid tumors, quality of life among patients receiving treatment for T cell lymphoma and updates on the Cancer Moonshot during the Biden Cancer Initiative Colloquium at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting, being held June 1-5 in Chicago. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 1, 2018 Category: Cancer & Oncology Source Type: news

FDA OKs First Artificial Iris for Aniridia, Other Iris Defects FDA OKs First Artificial Iris for Aniridia, Other Iris Defects
The CustomFlex Artificial Iris treats adults and children with congenital aniridia or iris defects due to other reasons or conditions, such as albinism, traumatic injury, or surgical removal due to melanoma.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 30, 2018 Category: Consumer Health News Tags: Ophthalmology News Alert Source Type: news

FDA clears first artificial iris from HumanOptics
The FDA today granted pre-market approval and a breakthrough device designation for HumanOptics‘ CustomFlex artificial iris, touting it as the first stand-alone prosthetic iris to win approval in the US. The CustomFlex artificial iris is designed to be surgically implanted in adults and children to treat individuals whose iris is completely missing or damaged due to either a congenital condition called aniridia or other damage to the eye, according to an FDA release. The newly cleared device is also indicated to treat iris defects due to other reasons or conditions, such as albinism, traumatic injury or surgical remo...
Source: Mass Device - May 30, 2018 Category: Medical Devices Authors: Fink Densford Tags: Food & Drug Administration (FDA) Optical/Ophthalmic Pre-Market Approval (PMA) Regulatory/Compliance humanoptics Source Type: news

FDA Approves First Artificial Iris
A German company has become the first to score FDA approval for a stand-alone prosthetic iris in the United States. The agency said Wednesday afternoon that it approved the CustomFlex Artificial Iris, made by Erlangen, Germany-based HumanOptics. The device, which is surgically implanted, is approved to treat adults and children whose iris is completely missing or damaged due to a congenital condition called aniridia or other damage to the eye. “Patients with iris defects may experience severe vision problems, as well as dissatisfaction with the appearance of their eye,” said Malvina Eydelman, MD, dire...
Source: MDDI - May 30, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Implants Source Type: news

Parents of two children who died of a cancer that 95% survive are suing doctor
Damian Creed and Salette Ruiz were both diagnosed with retinoblastoma aged two in Miami, Florida. Though 95 percent of sufferers survive, Damian and Salette died the same week in 2016. (Source: the Mail online | Health)
Source: the Mail online | Health - May 18, 2018 Category: Consumer Health News Source Type: news

Tanzania:Eye Cancer - Save Children
[Citizen] Recent revelations that more than half of the children under the age of 5, who are diagnosed with eye cancer in the country die, should worry everyone and jolt the authorities to action. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 18, 2018 Category: African Health Source Type: news

Jarrow toddler diagnosed with deadly eye cancer from a photograph
During a family trip to Tenerife in January 2017, a photographer snapped Presley, who was just seven months old at the time. The photographer, noticed Presley had one white eye in the picture. (Source: the Mail online | Health)
Source: the Mail online | Health - May 18, 2018 Category: Consumer Health News Source Type: news

Toddler, two, was diagnosed with deadly eye cancer from a photograph
During a family trip to Tenerife in January 2017, a photographer snapped Presley, who was just seven months old at the time. The photographer, noticed Presley had one white eye in the picture. (Source: the Mail online | Health)
Source: the Mail online | Health - May 18, 2018 Category: Consumer Health News Source Type: news

Tanzania:Eye Cancer in Children 'Worrying'
[Citizen] Dar es Salaam -Experts in Tanzania have raised concerns about rising cases of eye cancer also known as Retinoblastoma, which commonly affects children. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - May 17, 2018 Category: African Health Source Type: news

Doctors Stumped By Rare Eye Cancer Cases In North Carolina, Alabama
Ocular melanoma typically affects six out of every 1 million people, but doctors have found dozens of cases where the patients have connections to either Huntersville, N.C., or Auburn, Ala. (Image credit: Karen Bleier/AFP/Getty Images) (Source: NPR Health and Science)
Source: NPR Health and Science - May 4, 2018 Category: Consumer Health News Authors: Samantha Raphelson Source Type: news

CBS News report on rare eye cancer gets widespread response
A CBS News report about a rare eye cancer affecting people in Georgia and North Carolina is getting reaction from around the world. Many people say they or someone they know has also been diagnosed with ocular melanoma. CBS News correspondent Anna Werner has the latest. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - May 3, 2018 Category: Consumer Health News Source Type: news

After CBS News report on rare eye cancer mystery, hundreds share similar stories
Doctors are intensifying efforts to find out what caused groups of people in two different cities to mysteriously develop ocular melanoma (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - May 3, 2018 Category: Consumer Health News Source Type: news

After CBS News report on rare eye cancer mystery, hundreds share stories
Doctors are intensifying efforts to find out what caused groups of people in two different cities to mysteriously develop a rare eye cancer. Ocular melanoma typically occurs in just six out of every one million people. After our report Monday, hundreds of people reached out to say they or someone they know have had this same rare cancer. Anna Werner reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - May 3, 2018 Category: Consumer Health News Source Type: news

In Retinoblastoma Survivors, Oculo - Visual Issues Tied to QoL
Oculo - visual problems associated with functional status, vision - targeted health - related quality of life (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - May 2, 2018 Category: Cancer & Oncology Tags: Oncology, Ophthalmology, Journal, Source Type: news

Morning Break: Stolen Trump Records; Gyns in Trouble; Eye Cancer Cluster?
(MedPage Today) -- Health news and commentary from around the Web gathered by the MedPage Today staff (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - May 2, 2018 Category: American Health Source Type: news

In Retinoblastoma Survivors, Oculo-Visual Issues Tied to QoL
WEDNESDAY, May 2, 2018 -- Oculo-visual problems among adult retinoblastoma survivors are associated with patient-reported vision-targeted health-related quality of life (HRQoL), according to a study published online April 26 in JAMA... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - May 2, 2018 Category: Pharmaceuticals Source Type: news

Group of rare eye cancer cases baffles experts
A group of patients with a rare type of eye cancer called ocular melanoma has researchers and epidemiologists stumped. (Source: CNN.com - Health)
Source: CNN.com - Health - May 1, 2018 Category: Consumer Health News Source Type: news

Doctors Fret Over Cases of Rare Eye Cancer
Ocular melanoma typically occurs in just six of every one million people, but has been diagnosed in a group of 18 patients in North Carolina and Alabama. (Source: WebMD Health)
Source: WebMD Health - May 1, 2018 Category: Consumer Health News Source Type: news

Diseases spread by ticks, mosquitoes and fleas more than tripled in the U.S.
The warmer weather of spring and summer means the start of tick and mosquito season and the diseases they transmit, including Lyme disease, Rocky Mountain spotted fever, West Nile and Zika. A new report from the Centers for Disease Control and Prevention has found that illnesses from mosquito, tick and flea bites more than tripled in […]Related:Liquid nicotine for e-cigs looks like kids’ juice boxes and candy, government saysShe modeled in New York and worked for the Navy. At 93, parasites ate her alive at a nursing home.A rare eye cancer showed up in three friends. Doctors want to know if the cases are c...
Source: Washington Post: To Your Health - May 1, 2018 Category: Consumer Health News Source Type: news

Medical mystery shines light on rare eye cancer
A closer look at ocular melanoma, an extremely rare form of cancer that has been identified in groups of patients in two states (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - May 1, 2018 Category: Consumer Health News Source Type: news

She modeled in New York and worked for the Navy. At 93, parasites ate her alive at a nursing home.
Pictures of Rebecca Zeni during her younger years showed her with flawless skin, well-defined eyebrows and long, thick lashes. Her hair, parted in the middle, was neatly tied with a bow behind her ear. Her beauty could capture a room, her daughter said, but she was more than just a beautiful face. She was a modern-day […]Related:A rare eye cancer showed up in three friends. Doctors want to know if the cases are connected.CDC director asks that his $375,000 salary be cut after questions raisedA scientist just turned 104. His birthday wish is to die. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - May 1, 2018 Category: Consumer Health News Source Type: news

A rare eye cancer showed up in three friends. Doctors want to know if the cases are connected.
At least a dozen and a half people have been diagnosed with a rare form of eye cancer in two locations in North Carolina and Alabama, leaving medical experts mystified about the cause. Ocular melanoma occurs in about six out of every 1 million people, according CBS News and at least 18 people who have been […]Related:CDC director asks that his $375,000 salary be cut after questions raisedA scientist just turned 104. His birthday wish is to die.A doctor flew into a sudden rage and threatened to decapitate, disembowel employees and patients (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - April 30, 2018 Category: Consumer Health News Source Type: news

Rare eye cancer affects 2 groups of people in N.C. and Alabama
Researchers want to know what may be causing ocular melanoma, a rare eye cancer in two states. First, a group of 18 patients were identified in Huntersville, North Carolina. Now there's a second group in Auburn, Alabama, home of Auburn University. CBS News correspondent Anna Werner reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - April 30, 2018 Category: Consumer Health News Source Type: news

Eye cancer mystery baffles doctors
Usually found in just six in one million people, ocular melanoma has been identified in 18 people in Huntersville, N.C. and a group of former Auburn students (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - April 30, 2018 Category: Consumer Health News Source Type: news

"What's going on?" Rare form of eye cancer detected in two groups
Ocular melanoma, usually found in just six of every one million people, has been identified in patients from Huntersville, N.C., and in a group of former Auburn University students (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - April 30, 2018 Category: Consumer Health News Source Type: news

"What's going on?" Extremely rare form of eye cancer detected in 2 groups
Ocular melanoma, usually found in just six of every one million people, has been identified in patients from Huntersville, N.C., and in a group of former Auburn University students (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - April 30, 2018 Category: Consumer Health News Source Type: news

Rare eye cancer affects two groups of people in N.C. and Alabama
Researchers want to know what may be causing ocular melanoma, a rare eye cancer in two states. First, a group of 18 patients were identified in Huntersville, North Carolina. Now there's a second group in Auburn, Alabama, home of Auburn University. Anna Werner reports. (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - April 30, 2018 Category: Consumer Health News Source Type: news

Selumetinib Fails to Improve Outcomes With Dacarbazine in Uveal Melanoma
The combination of selumetinib with dacarbazine did not offer improved survival outcomes over placebo/dacarbazine in patients with metastatic uveal melanoma. (Source: CancerNetwork)
Source: CancerNetwork - March 20, 2018 Category: Cancer & Oncology Authors: Dave Levitan Tags: Melanoma News Source Type: news

Study shows need for early support among people with uveal melanoma
FINDINGSUCLA researchers found that nearly all people diagnosed with uveal melanoma had a number of unmet psychological and health information needs, particularly during the first three months after their diagnoses. The study is the first to examine long-term supportive care needs among patients with this disease, and suggested there are more acute needs among people with uveal melanoma than people with other cancers. Social and psychological circumstances that affect these patients, such as personality factors, the social support they receive and the size of their social network, contributed more to a greater need for sup...
Source: UCLA Newsroom: Health Sciences - March 5, 2018 Category: Universities & Medical Training Source Type: news

Retinoblastoma Eye Cancer
Retinoblastoma (Eye Cancer) (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 20, 2018 Category: General Medicine Source Type: news

Boston Doctors Try To Save Girl ’ s Vision Using New Cancer Treatment
BOSTON (CBS) – It’s a parent’s worst nightmare, hearing not only that your child has cancer but that she might also lose her eye. That’s exactly what happened to an Andover family and their 3-year-old daughter. But as Dr. Mallika Marshall reports, doctors at Boston Children’s Hospital are using a revolutionary technique to try to save her vision and her life. A little over a year ago Dania Snyder was a typical toddler until her parents noticed something unusual about her right eye. “You could see a little flash of a fleshy piece sort of through her pupil,” explains PJ, Dania’...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 23, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health Local News Syndicated Local Boston Children's Hospital Cancer Dr. Mallika Marshall Source Type: news

Wills Eye Hospital hosts presentation of inaugural Brady Shields Chair
(Wills Eye Hospital) Renowned Eye Cancer specialist, Dr. Jerry Shields receives the first distinguished Brady-Shields Chair in Ocular Oncology. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - January 18, 2018 Category: International Medicine & Public Health Source Type: news

Rare form of deadly eye cancer normally diagnosed in older men is killing young women in North Carolina – and doctors don’t know why
(Natural News) Ophthalmologists in North Carolina were reportedly baffled by the increasing cases of an eye cancer known as ocular melanoma across the state, which affected nearly two dozen people and killed four patients within a 15-mile radius of Huntersville. According to experts, the eye disease affects five in one million patients and may commonly manifest in older men in... (Source: NaturalNews.com)
Source: NaturalNews.com - January 11, 2018 Category: Consumer Health News Source Type: news

Eye cancer cluster affects dozens in North Carolina
Nearly two dozen cases of ocular melanoma have been diagnosed in and near Huntersville, North Carolina, and researchers have not found any environmental or genetic link. (Source: the Mail online | Health)
Source: the Mail online | Health - January 6, 2018 Category: Consumer Health News Source Type: news

Mother with rare eye cancer gives birth to healthy twins
Jessica Boesmiller, 37, from Charlotte, North Carolina, was diagnosed with ocular melanoma while eight months pregnant and had her right eye removed three weeks later. (Source: the Mail online | Health)
Source: the Mail online | Health - January 2, 2018 Category: Consumer Health News Source Type: news

Intravitreous Chemo Poses Minimal Extraocular Extension Risk in Retinoblastoma Intravitreous Chemo Poses Minimal Extraocular Extension Risk in Retinoblastoma
Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 8, 2017 Category: Consumer Health News Tags: Medscape Today News Source Type: news