One reason brain tumors are more common in men
New research helps explain why brain tumors occur more often in males and frequently are more harmful. For example, glioblastomas, the most common malignant brain tumors, are diagnosed twice as often in males, who suffer greater cognitive impairments than females and do not survive as long. The researchers found that retinoblastoma protein, a protein known to reduce cancer risk, is significantly less active in male brain cells than in female brain cells. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - August 2, 2014 Category: Science Source Type: news
Drug shows promise for the first time against metastatic melanoma of the eye
For the first time, a therapy has been found that can delay progression of metastatic uveal melanoma, a rare and deadly form of melanoma of the eye. Results from a multicenter clinical trial show that a new drug called selumetinib increases progression-free survival, the length of time during and after treatment that a patient with metastases lives with the disease without it progressing. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 19, 2014 Category: Science Source Type: news
Drug shows promise for the first time against metastatic melanoma of the eye
(Columbia University Medical Center) For the first time, a therapy has been found that can delay progression of metastatic uveal melanoma, a rare and deadly form of melanoma of the eye. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 19, 2014 Category: Biology Source Type: news
Selumetinib Yields Modest Benefits in Rare Eye CancerSelumetinib Yields Modest Benefits in Rare Eye Cancer
The first randomized controlled trial of the MEK inhibitor selumetinib finds modest improvement in clinical outcomes of advanced uveal melanoma but high rates of adverse effects. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 17, 2014 Category: Cancer & Oncology Tags: Hematology-Oncology News Source Type: news
Study compares survival for treatments of uncommon eye cancer
(The JAMA Network Journals) In patients with advanced uveal melanoma, treatment with the agent selumetinib, compared with chemotherapy, resulted in an improved cancer progression-free survival time and tumor response rate, but no improvement in overall survival, according to a study in the June 18 issue of JAMA. The modest improvement in clinical outcomes was accompanied by a high rate of adverse events. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 17, 2014 Category: Cancer & Oncology Source Type: news
Analyzing RB and E2F During the G1–S Transition
The G1/S-phase restriction point is an important landmark in the mammalian cell division cycle. The key regulator of the G1/S transition is the retinoblastoma gene product (pRB). It prevents the transcription of genes required for S-phase progression by repressing E2F transcription factors. An increase in Cdk phosphorylation of pRB causes the release of E2F transcription factors and advancement into S phase. Here we describe two simple techniques used to assess pRB phosphorylation and E2F transcription during G1/S progression. (Source: Springer protocols feed by Cell Biology)
Source: Springer protocols feed by Cell Biology - June 10, 2014 Category: Cytology Source Type: news
“White Eye” Photos May Be Sign Of Serious Disease
BOSTON (CBS) – “Red Eyes” are a common frustration when it comes to taking pictures. But doctors are warning parents that “White Eyes” in a child’s photo can be an indication of a serious medical condition.
In rare cases, it can be a sign of retinoblastoma, a cancer of the eye. “It can spread outside the eye and be fatal if it is not picked up,” said Dr. Michael Hunt, a pediatric eye specialist.
That was Makenzie Foreman’s diagnosis. She had tumors in her left eye and began chemotherapy when she was just six months old. Her eye eventually had to be removed.
“It was obviously extremely emotional,...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 7, 2014 Category: Consumer Health News Authors: deanreddington Tags: Health Local News Seen On WBZ-TV Syndicated Local Watch Listen Cancer Dr. Mallika Marshall retinoblastoma white eye Source Type: news
Animal Trials Show Promise for Treating Eye Cancer
Title: Animal Trials Show Promise for Treating Eye CancerCategory: Health NewsCreated: 5/29/2014 4:35:00 PMLast Editorial Review: 5/30/2014 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - May 30, 2014 Category: Cancer & Oncology Source Type: news
Animal Trials Show Promise for Treating Eye Cancer
Researchers target genetic mutations common among uveal melanoma patients (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - May 29, 2014 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Nursing, Oncology, Ophthalmology, Research, News, Source Type: news
Melanoma of the eye caused by two gene mutations
A therapeutic target for treating the most common form of eye cancer in adults has been identified by researchers. They have also, in experiments with mice, been able to slow eye tumor growth with an existing FDA-approved drug. The researchers looked specifically at uveal melanoma. Uveal collectively refers to parts of the eye, notably the iris, that contain pigment cells. As with melanoma skin cancer, uveal melanoma is a malignancy of these melanin-producing cells. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 29, 2014 Category: Science Source Type: news
Melanoma of the eye caused by 2 gene mutations
(University of California - San Diego) Researchers at the University of California, San Diego School of Medicine have identified a therapeutic target for treating the most common form of eye cancer in adults. They have also, in experiments with mice, been able to slow eye tumor growth with an existing FDA-approved drug. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 29, 2014 Category: Cancer & Oncology Source Type: news
The Royle Family star Caroline Aherne reveals she is fighting lung cancer
Caroline Aherne has fought bladder and eye cancer in the past and is now facing lung cancer (Source: Telegraph Health)
Source: Telegraph Health - May 13, 2014 Category: Consumer Health News Source Type: news
New way to enhance nerve growth following injury discovered
A mechanism to promote growth in damaged nerve cells as a means to restore connections after injury has been uncovered by scientists who have discovered a key molecule that directly regulates nerve cell growth in the damaged nervous system. "We made the surprising discovery that a protein called Retinoblastoma (Rb) is present in adult neurons," explains the lead researcher. "This protein appears to normally act as a brake -- preventing nerve growth." (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - April 22, 2014 Category: Science Source Type: news
Mum diagnoses eye cancer in her three-year-old son by using camera flash
THE mother of a toddler who is battling a serious illness advises parents that spotting a tumour in your child's eye can be as simple as taking a photograph (Source: Daily Express - Health)
Source: Daily Express - Health - April 9, 2014 Category: Consumer Health News Source Type: news
Model diagnosed with rare eye cancer blames using sunbeds without goggles
Mother-of-one Debi Gibson from Stoke-on-Trent, Staffordshire, pictured with her husband and daughter left, starting using sunbeds at the age of 14. (Source: the Mail online | Health)
Source: the Mail online | Health - April 6, 2014 Category: Consumer Health News Source Type: news
