Expanding Our Horizons: Editorial Comment on “The Effect of Laparoscopic Gastric Ischemic Preconditioning Prior to Esophagectomy on Anastomotic Stricture Rate with Comparison to Esophagectomy-Alone Controls”
(Source: Annals of Surgical Oncology)
Source: Annals of Surgical Oncology - April 3, 2024 Category: Cancer & Oncology Source Type: research

Cancers, Vol. 16, Pages 1378: Chemotherapy Plus Atezolizumab Pre- and Post-Resection in Localized Esophageal or Gastroesophageal Junction Adenocarcinomas: A Phase I/II Single-Arm Study
arry Lyons Norelle Reilly James C. Yao Jaffer A. Ajani Mariela Blum Murphy Efforts to improve the prognosis for patients with locally advanced esophageal or gastroesophageal junction (GEJ) adenocarcinoma have focused on neoadjuvant approaches to increase the pathological complete response (pathCR) rate, improve surgical resection, and prolong event-free and overall survival (OS). Building on the recent evidence that PD-1 inhibition plus chemotherapy improves the OS of patients with metastatic GEJ adenocarcinoma, we evaluated whether the application of this strategy in the neoadjuvant setting would improve the p...
Source: Cancers - March 31, 2024 Category: Cancer & Oncology Authors: Matheus Sewastjanow-Silva Lianchun Xiao Graciela N. Gonzalez Xuemei Wang Wayne Hofstetter Stephen Swisher Reza Mehran Boris Sepesi Manoop S. Bhutani Brian Weston Emmanuel Coronel Rebecca E. Waters Jane E. Rogers Jackie Smith Larry Lyons Norelle Reilly Jam Tags: Article Source Type: research

Comparison of clinical outcomes of robotic-assisted and video-assisted esophagectomy for esophageal cancer
CONCLUSION: Robotic procedures can be safely performed in esophageal cancers with complication rates and oncological radicality similar to those of other minimally invasive techniques.PMID:38554354 | DOI:10.4103/jcrt.jcrt_2518_22 (Source: Cell Research)
Source: Cell Research - March 30, 2024 Category: Cytology Authors: Sercan Y üksel U ğur Topal Mehmet Z Song ür İsmail Çalıkoğlu Erdal Karak öse Erdal Ercan Zafer Teke Hasan Bekta ş Source Type: research

Lymph node volume predicts survival in esophageal squamous cell carcinoma treated with neoadjuvant chemoradiotherapy and surgery
In conclusion, this study demonstrated that large LN volume is correlated with poor OS, DFS, and locoregional control in ESCC treated with neoadjuvant CCRT and esophagectomy.PMID:38547184 | DOI:10.1371/journal.pone.0300173 (Source: Cancer Control)
Source: Cancer Control - March 28, 2024 Category: Cancer & Oncology Authors: Tzu-Hui Pao Ying-Yuan Chen Wei-Lun Chang Shang-Yin Wu Wu-Wei Lai Yau-Lin Tseng Ta-Jung Chung Forn-Chia Lin Source Type: research

Does the time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery affect outcomes for locally advanced esophageal squamous cell carcinoma?
CONCLUSIONS: Locally advanced ESCC patients with time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery > 8 weeks were associated with worse long-term survival.PMID:38536527 | DOI:10.1007/s00432-024-05696-4 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - March 27, 2024 Category: Cancer & Oncology Authors: Jiacong Liu Linhai Zhu Xuhua Huang Zhongjie Lu Yanye Wang Yuhong Yang Jiayue Ye Chen Gu Wang Lv Chong Zhang Jian Hu Source Type: research

Does the time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery affect outcomes for locally advanced esophageal squamous cell carcinoma?
CONCLUSIONS: Locally advanced ESCC patients with time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery > 8 weeks were associated with worse long-term survival.PMID:38536527 | DOI:10.1007/s00432-024-05696-4 (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - March 27, 2024 Category: Cancer & Oncology Authors: Jiacong Liu Linhai Zhu Xuhua Huang Zhongjie Lu Yanye Wang Yuhong Yang Jiayue Ye Chen Gu Wang Lv Chong Zhang Jian Hu Source Type: research

Neoadjuvant chemoimmunotherapy for locally advanced esophageal squamous cell carcinoma: Data from literature review and a real ‐world analysis
ConclusionNCIT is safe and provides potential survival benefits for patients with locally advanced ESCC. However, randomized phase 3 trial data is still needed. (Source: Thoracic Cancer)
Source: Thoracic Cancer - March 27, 2024 Category: Cancer & Oncology Authors: Yao Zhang, Huiting Li, Bo Yu, Si Sun, Zhihuang Hu, Xianghua Wu, Yang Zhang, Bin Li, Yawei Zhang, Jiaqing Xiang, Jialei Wang, Hui Yu Tags: ORIGINAL ARTICLE Source Type: research

Does the time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery affect outcomes for locally advanced esophageal squamous cell carcinoma?
ConclusionsLocally advanced ESCC patients with time interval from neoadjuvant camrelizumab combined with chemotherapy to surgery  >  8 weeks were associated with worse long-term survival. (Source: Journal of Cancer Research and Clinical Oncology)
Source: Journal of Cancer Research and Clinical Oncology - March 27, 2024 Category: Cancer & Oncology Source Type: research

Influence of Neoadjuvant Immunotherapy-Chemotherapy on Perioperative Outcomes in Locally Advanced Esophageal Adenocarcinoma
CONCLUSION: The addition of immunotherapy to neoadjuvant chemotherapy for locally advanced esophageal adenocarcinoma does not appear to alter perioperative short-term outcomes significantly after esophagectomy.PMID:38530527 | DOI:10.1245/s10434-024-15186-z (Source: Ann Oncol)
Source: Ann Oncol - March 26, 2024 Category: Cancer & Oncology Authors: Yehonatan Nevo James Tankel Hedi Zhao Jaime Ramirez Jonathan Cools-Lartigue Carmen Muller Thierry Alcindor Lorenzo Ferri Source Type: research

Rapid formation of aortoesophageal fistula complicated by mycotic thoracic aortic aneurysm secondary to infective endocarditis
Rev Esp Enferm Dig. 2024 Mar 25. doi: 10.17235/reed.2024.10397/2024. Online ahead of print.ABSTRACTA 73-year-old man was admitted with four weeks of intermittent fever. He had a history of total aortic arch replacement for aortic arch aneurysm four years prior. CT scans showed no abnormalities before admission. Repeated blood cultures yielded Streptococcus anginosus and Prevotella melaninogenica, suggesting infective endocarditis (IE). Transesophageal echocardiography revealed a vegetation on the aortic valve, confirming IE. He suddenly presented with massive hematemesis and hypotension. Endoscopy revealed an elevated lesi...
Source: Revista Espanola de Enfermedades Digestivas - March 25, 2024 Category: Gastroenterology Authors: Maki Setake Yasuhiro Uechi Yuzuru Kinjo Masaru Miyazato Noriya Nakachi Ryosaku Tomiyama Namio Higa Akira Hokama Source Type: research