Effect of Potassium Permanganate on Staphylococcal Isolates Derived from the Skin of Patients with Atopic Dermatitis
Acta Derm Venereol. 2024 Feb 28;104:adv18642. doi: 10.2340/actadv.v104.18642.ABSTRACTIn atopic dermatitis (AD), Staphylococcus aureus frequently colonizes lesions, leading to superinfections that can then lead to exacerbations. The presence of biofilm-producing isolates has been associated with worsening of the disease. Potassium permanganate is used as a topical treatment of infected eczema, blistering conditions, and wounds. Little is known of its effects against microbes in AD skin. The aim of this study was to explore antibacterial and antibiofilm properties of potassium permanganate against staphylococcal isolates der...
Source: Acta Derm Venereol A... - February 28, 2024 Category: Dermatology Authors: Sigrid Lundgren Andreas Sonesson Source Type: research

Effect of Potassium Permanganate on Staphylococcal Isolates Derived from the Skin of Patients with Atopic Dermatitis
Acta Derm Venereol. 2024 Feb 28;104:adv18642. doi: 10.2340/actadv.v104.18642.ABSTRACTIn atopic dermatitis (AD), Staphylococcus aureus frequently colonizes lesions, leading to superinfections that can then lead to exacerbations. The presence of biofilm-producing isolates has been associated with worsening of the disease. Potassium permanganate is used as a topical treatment of infected eczema, blistering conditions, and wounds. Little is known of its effects against microbes in AD skin. The aim of this study was to explore antibacterial and antibiofilm properties of potassium permanganate against staphylococcal isolates der...
Source: Acta Derm Venereol A... - February 28, 2024 Category: Dermatology Authors: Sigrid Lundgren Andreas Sonesson Source Type: research

Effect of Potassium Permanganate on Staphylococcal Isolates Derived from the Skin of Patients with Atopic Dermatitis
Acta Derm Venereol. 2024 Feb 28;104:adv18642. doi: 10.2340/actadv.v104.18642.ABSTRACTIn atopic dermatitis (AD), Staphylococcus aureus frequently colonizes lesions, leading to superinfections that can then lead to exacerbations. The presence of biofilm-producing isolates has been associated with worsening of the disease. Potassium permanganate is used as a topical treatment of infected eczema, blistering conditions, and wounds. Little is known of its effects against microbes in AD skin. The aim of this study was to explore antibacterial and antibiofilm properties of potassium permanganate against staphylococcal isolates der...
Source: Acta Dermato-Venereologica - February 28, 2024 Category: Dermatology Authors: Sigrid Lundgren Andreas Sonesson Source Type: research

CrAss-Like Phages: From Discovery in Human Fecal Metagenome to Application as a Microbial Source Tracking Marker
AbstractCrAss-like phages are a diverse group of bacteriophages genetically similar to the prototypical crAssphage (p-crAssphage), which was discovered in the human gut microbiome through a metagenomics approach. It was identified as a ubiquitous and highly abundant bacteriophage group in the gut microbiome. Initial co-occurrence analysis postulatedBacteroides spp. as the prospective bacterial host. Subsequent studies have confirmed multiple host species under Phylum Bacteroidetes and some Firmicutes. Detection of crAss-like phages in sewage-contaminated environmental water and robust correlation with enteric viruses and b...
Source: Food and Environmental Virology - February 27, 2024 Category: Virology Source Type: research

Genes, Vol. 15, Pages 285: Full-Length Transcriptome Sequencing and RNA-Seq Analysis Offer Insights into Terpenoid Biosynthesis in Blumea balsamifera (L.) DC.
Yuxin Pang Blumea balsamifera (L.) DC., an important economic and medicinal herb, has a long history of being used as a traditional Chinese medicine. Its leaves have always been used as a raw material for the extraction of essential oils, comprising large amounts of terpenoids, which have good therapeutic effects on many diseases, such as eczema, bacterial infection, and hypertension. However, the genetic basis of terpenoid biosynthesis in this plant is virtually unknown on account of the lack of genomic data. Here, a combination of next-generation sequencing (NGS) and full-length transcriptome sequencing was applie...
Source: Genes - February 24, 2024 Category: Genetics & Stem Cells Authors: Zhigang Ju Lin Liang Yaqiang Zheng Hongxi Shi Wenxuan Zhao Wei Sun Yuxin Pang Tags: Article Source Type: research

Anti-psoriatic characteristics of ROCEN (topical Arthrocen) in comparison with Cyclosporine A in a murine model
Topical ROCEN (Roc), liposomal arthrocen hydrogel, is a robust anti-inflammatory formulation which has been developed for skin diseases such as eczema. Therefore, we aimed to evaluate the efficacy of Roc 2% on... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - February 24, 2024 Category: Complementary Medicine Authors: Ramin Goudarzi, Min-Ho  Kim and Alireza Partoazar Tags: Research Source Type: research

Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis
Conclusions: Topical application of emollients containing coconut oil- and sunflower seed oil-derived fatty esters may improve itch, reduce topical steroid use, and reduce the relative abundance of S. aureus in mild-to-moderate AD. CTR number: NCT04831892.PMID:38394048 | DOI:10.1089/derm.2023.0329 (Source: Dermatitis)
Source: Dermatitis - February 23, 2024 Category: Dermatology Authors: Dawnica Nadora Waqas Burney Ratan K Chaudhuri Aidan Galati Mildred Min Sydney Fong Kenny Lo Cindy J Chambers Raja K Sivamani Source Type: research

Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis
Conclusions: Topical application of emollients containing coconut oil- and sunflower seed oil-derived fatty esters may improve itch, reduce topical steroid use, and reduce the relative abundance of S. aureus in mild-to-moderate AD. CTR number: NCT04831892.PMID:38394048 | DOI:10.1089/derm.2023.0329 (Source: Dermatitis)
Source: Dermatitis - February 23, 2024 Category: Dermatology Authors: Dawnica Nadora Waqas Burney Ratan K Chaudhuri Aidan Galati Mildred Min Sydney Fong Kenny Lo Cindy J Chambers Raja K Sivamani Source Type: research

Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis
Conclusions: Topical application of emollients containing coconut oil- and sunflower seed oil-derived fatty esters may improve itch, reduce topical steroid use, and reduce the relative abundance of S. aureus in mild-to-moderate AD. CTR number: NCT04831892.PMID:38394048 | DOI:10.1089/derm.2023.0329 (Source: Dermatitis)
Source: Dermatitis - February 23, 2024 Category: Dermatology Authors: Dawnica Nadora Waqas Burney Ratan K Chaudhuri Aidan Galati Mildred Min Sydney Fong Kenny Lo Cindy J Chambers Raja K Sivamani Source Type: research

Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis
Conclusions: Topical application of emollients containing coconut oil- and sunflower seed oil-derived fatty esters may improve itch, reduce topical steroid use, and reduce the relative abundance of S. aureus in mild-to-moderate AD. CTR number: NCT04831892.PMID:38394048 | DOI:10.1089/derm.2023.0329 (Source: Dermatitis)
Source: Dermatitis - February 23, 2024 Category: Dermatology Authors: Dawnica Nadora Waqas Burney Ratan K Chaudhuri Aidan Galati Mildred Min Sydney Fong Kenny Lo Cindy J Chambers Raja K Sivamani Source Type: research

Prospective Randomized Double-Blind Vehicle-Controlled Study of Topical Coconut and Sunflower Seed Oil-Derived Isosorbide Diesters on Atopic Dermatitis
Conclusions: Topical application of emollients containing coconut oil- and sunflower seed oil-derived fatty esters may improve itch, reduce topical steroid use, and reduce the relative abundance of S. aureus in mild-to-moderate AD. CTR number: NCT04831892.PMID:38394048 | DOI:10.1089/derm.2023.0329 (Source: Dermatitis)
Source: Dermatitis - February 23, 2024 Category: Dermatology Authors: Dawnica Nadora Waqas Burney Ratan K Chaudhuri Aidan Galati Mildred Min Sydney Fong Kenny Lo Cindy J Chambers Raja K Sivamani Source Type: research

Janus kinase inhibitors in atopic dermatitis: an umbrella review of meta-analyses
ConclusionCompared to placebo or dupilumab, the administration of JKIs can ameliorate IGA response more effectively, improve the EASI75, and relieve pruritus without severe adverse effect, while accompanied by more acne, nasopharyngitis, headache, and digestive disturbances. The curative effect of 200 mg of abrocitinib is significant and more caution should be given in patients with gastrointestinal dysfunction, herpes zoster, and those who are acne-prone. Baricitinib and upadacitinib should be avoided in populations at high risk for cardiovascular events.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/di...
Source: Frontiers in Immunology - February 23, 2024 Category: Allergy & Immunology Source Type: research

Kaposi varicelliform eruption: an unusual presentation caused by varicella zoster virus in a healthy adult patient - a case report
CONCLUSION: This case underscores the importance of prompt KVE identification and consideration of antiviral therapy to enhance patient outcomes. Further research is warranted to elucidate predisposing factors for this rare condition.PMID:38388418 | DOI:10.1186/s12879-024-09115-4 (Source: Herpes)
Source: Herpes - February 22, 2024 Category: Infectious Diseases Authors: Hassan El-Masry Safia Essam Hamed Gaber Nour Shaheen Ahmed Abdelbary Naglaa Mohamed Sayed Salma Samir Omar Source Type: research

Kaposi varicelliform eruption: an unusual presentation caused by varicella zoster virus in a healthy adult patient - a case report
Kaposi Varicelliform Eruptions (KVE), also known as eczema herpeticum, is a rare and potentially life-threatening dermatological condition primarily attributed to herpes simplex virus (HSV) infection, with les... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - February 22, 2024 Category: Infectious Diseases Authors: Hassan El-Masry, Safia Essam, Hamed Gaber, Nour Shaheen, Ahmed Abdelbary, Naglaa Mohamed Sayed and Salma Samir Omar Tags: Case Report Source Type: research

Dietary Intervention for Control of Clinical Symptom in Patients with Systemic Metal Allergy: A Single Center Randomized Controlled Clinical Study
In conclusion, dietary intervention by a registered dietitian is effective in improving skin symptoms with a reduction in metal intake.PMID:38379275 | DOI:10.24546/0100486230 (Source: Kobe J Med Sci)
Source: Kobe J Med Sci - February 21, 2024 Category: General Medicine Authors: Reiko Mikajiri Atsushi Fukunaga Makoto Miyoshi Noriaki Maeshige Ken Washio Taro Masaki Chikako Nishigori Ikuko Yamamoto Akiyo Toda Michiko Takahashi Shun-Ichiro Asahara Yoshiaki Kido Makoto Usami Source Type: research