Fight Aging! Newsletter, January 30th 2023
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes. Communication Between Blood and Brain in Aging and Rejuvenation https://www.fightaging.org/archives/2023/01/communication-between-blood-and-brain-in-aging-and-rejuvenation/ As noted here, joining the circulatory systems of an old and young mouse results in some degree of rejuvenation in the old mouse. Where brain function is improved, researchers are inte...
Source: Fight Aging! - January 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Clearing Senescent Cells as a Treatment for Type 2 Diabetes
In conclusion, deletion of p16Ink4a cells did not negatively impact beta-cell mass and blood glucose under basal and HFD conditions and proliferation was restored in a subset of HFD mice opening further therapeutic targets in the treatment of diabetes. Link: https://doi.org/10.18632/aging.204483 (Source: Fight Aging!)
Source: Fight Aging! - January 26, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

The Fruit That Helps Weight Loss And Prevents Diabetes
A compound found only in this food can help stop type 2 diabetes and fight obesity. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 15, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Diabetes Source Type: blogs

The Mental Technique That Reduces Belly Fat
The way of thinking is linked to a 34 percent lower obesity risk. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - January 15, 2023 Category: Psychiatry & Psychology Authors: Jeremy Dean Tags: Weight Loss Source Type: blogs

Why body type standards are misleading in assessing health [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! In this episode, we explore the concept of normal weight obesity and skinny fat with scientific researcher Marc Nelson. Marc discusses how genetics, diet, exercise, and lifestyle all play a role in determining our body type, and how new research is helping us better Read more… Why body type standards are misleading in assessing health [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - January 14, 2023 Category: General Medicine Authors: Tags: Podcast Obesity Source Type: blogs

Health Equity and SDoH – 2023 Health IT Predictions
As we head into 2023, we wanted to kick off the new year with a series of 2023 Health IT predictions.  We asked the Healthcare IT Today community to submit their predictions and we received a wide ranging set of responses that we grouped into a number of themes.  Check out our communities predictions below and be sure to add your own thoughts and/or places you disagree with these predictions in the comments and on social media. Check out our community’s health equity and SDoH (Social Determinants of Health) predictions. Ted Quinn, CEO and founder at Activate Care Continued economic instability will put more America...
Source: EMR and HIPAA - January 10, 2023 Category: Information Technology Authors: John Lynn Tags: Health IT Company Healthcare IT 2023 Health IT Predictions Activate Care Adrienne Boissy Carenet Health Chelsea King Arthur Get Well Health Equity Matt Dickson Patient Discovery Qualtrics SDOH Social Determinants of Health Sunw Source Type: blogs

Weight Loss: Ozempic Could Be ‘ Game-Changing ’ Drug (Semaglutide)
Weekly injection of this anti-obesity medication could lead to a weight loss of 37 lb (17 kg). (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - December 29, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Weight Loss Source Type: blogs

Ozempic: The Obesity Drug That Leads To Dramatic Weight Loss
Once-a-week injection of this drug led overweight or obese people to lose more than a fifth of their weight. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - December 28, 2022 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Weight Loss Source Type: blogs

Fight Aging! Newsletter, December 26th 2022
This article on senolytic therapies to selectively remove senescent cells in old tissues is in part a matter of Unity Biotechnology talking up their position. The company suffered from first mover disadvantage in bringing senolytic drugs into clinical development. The field has made progress very rapidly over the last decade, and startups founded even just a couple of years after Unity's launch benefited from greater knowledge and a selection of better technologies to work with. Still, one can be talking up one's position and also be right. The accumulation of senescent cells is profoundly harmful, a significant contributi...
Source: Fight Aging! - December 25, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

On the Aging of the Kidneys
The longevity-associated gene klotho is known to act in kidney tissue, in ways that are protective of cell function in the aging environment of damage and inflammation. One of the conclusions that might be drawn from the extended life span produced by increased klotho expression in animal studies is that declining kidney function is an important aspect of aging. If the kidneys are not efficiently clearing waste from the bloodstream, and otherwise providing their contribution to bodily function, then all organs suffer as a result. Faster loss of kidney function means a faster decline into disease and mortality. The...
Source: Fight Aging! - December 23, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Correlations Between Gut Microbiome Composition and Longevity
A great deal of research is focused on cataloguing and correlating specific differences in the gut microbiome with aspects of aging. In years ahead, techniques will be developed to more precisely control the composition of the gut microbiome, removing issues such as too great a number of inflammatory microbes, or those producing harmful metabolites. At the moment, only more crude approaches such as fecal microbiota transplantation from a young donor are well developed. In principle it should be possible to take a probiotic approach and use oral administration to achieve a similar outcome, a rejuvenated gut microbiome, but ...
Source: Fight Aging! - December 22, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Republicanism is bad for your health . . .
 and might even kill you.Nancy Krieger and colleagues studied Covid-19 mortality rates and stress on hospital capacity in all 435 congressional districts, and its association with the political ideology of the relevant congresscritters and whether there was one-party control of state government. Abstract:MethodsWe analyzed observational cross-sectional data on COVID-19 mortality rates (age-standardized) and stress on hospital intensive care unit (ICU) capacity for all 435 US Congressional Districts (CDs) in a period of adult vaccine availability (April 2021 –March 2022). Political metrics comprised: (1) ideological ...
Source: Stayin' Alive - December 20, 2022 Category: American Health Source Type: blogs

Fight Aging! Newsletter, December 19th 2022
In conclusion, p16 deletion or p16 positive cell clearance could be a novel strategy preventing long term HFD-induced skin aging. Association of LDL-Cholesterol with Mortality https://www.fightaging.org/archives/2022/12/association-of-ldl-cholesterol-with-mortality/ Researchers here report on a study of LDL-cholesterol and mortality risk in older people. As they note, data on this topic is conflicted once one moves beyond the matter of cardiovascular disease. Over a lifetime, higher LDL-cholesterol makes it easier to reach the tipping point at which cholesterol deposited in blood vessel walls produces e...
Source: Fight Aging! - December 18, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Nutrition ’ s impact on pain and obesity [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! “Both pain and obesity can have a multitude of causes. Therefore, reducing pain and body weight should be approached in a multifactorial way; nutritionally, physically, mentally, and emotionally. Failure to do so may result in short-term success but long-term failure.” Francisco M. Torres is an Read more… Nutrition’s impact on pain and obesity [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - December 16, 2022 Category: General Medicine Authors: Tags: Podcast Obesity Pain Management Source Type: blogs

A High Fat Diet Promotes Cellular Senescence in Skin
In conclusion, p16 deletion or p16 positive cell clearance could be a novel strategy preventing long term HFD-induced skin aging. Link: https://doi.org/10.1155/2022/3415528 (Source: Fight Aging!)
Source: Fight Aging! - December 12, 2022 Category: Research Authors: Reason Tags: Daily News Source Type: blogs