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Fight Aging! Newsletter, April 3rd 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 2, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Glucagon-like Peptide-1 Receptor Agonists as an Approach to Modestly Slow Aging
Semaglutide is probably the best known of the glucagon-like peptide-1 receptor agonists, a class of drug deployed to treat type 2 diabetes and other consequences of obesity. This is one of a number of classes of diabetes drug where there is some suspicion that maybe these small molecules can modestly slow aging through much the same set of mechanisms that help to steer the abnormal metabolism of obesity and diabetes into a modestly less terrible state, e.g. reduced blood glucose and inflammatory signaling. Equally, the data to support that belief is far from compelling, and the effect sizes are small in comparison to, say,...
Source: Fight Aging! - March 29, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Bonus Features, ViVE Edition – March 27, 2023 – Amazon announces 23 startup partners, Divurgent and NTT DATA partner on IT transformation, plus product news from Care Evolution, Philips, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. This edition is a special dispatch from the first days of ViVE 2023. There have been a lot of new research reports, products, and partnerships announced in Nashville. We wanted to try and cover as many announcements for the Heal...
Source: EMR and HIPAA - March 27, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Bonus Features ViVE ViVE 2023 ViVE2023 Source Type: blogs

Bonus Features, ViVE Edition – March 27, 2023 – Amazon Web Services announces 23 startup partners, Divurgent and NTT DATA partner on IT transformation, plus product news from Care Evolution, Philips, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. This edition is a special dispatch from the first days of ViVE 2023. There have been a lot of new research reports, products, and partnerships announced in Nashville. We wanted to try and cover as many announcements for the Heal...
Source: EMR and HIPAA - March 27, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Bonus Features ViVE ViVE 2023 ViVE2023 Source Type: blogs

Fight Aging! Newsletter, March 27th 2023
This study has potentially significant implications in the field of OA as it provides a novel strategy for OA treatment. A Vicious Cycle of Heart Failure and Dementia https://www.fightaging.org/archives/2023/03/a-vicious-cycle-of-heart-failure-and-dementia/ The end of life is not pretty. The body is a failing machine of many complex essential parts, and the failures cascade and feed into one another as it breaks down. There is pain, loss of capacity, loss of the self as the brain runs down. There is a tendency to paper over the ugly reality in public discussion, to not talk about the facts of the matter...
Source: Fight Aging! - March 26, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Unlocking the secret to successful weight loss: Curiosity is the key
The obesity epidemic is reaching an all-time high. It’s no surprise why – the fitness industry pushing expensive diets and intense workouts, combined with limited access to affordable health care options, makes it difficult for people to maintain health in our society today. And what’s even more concerning? More than 72 percent of Americans are Read more… Unlocking the secret to successful weight loss: Curiosity is the key originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 21, 2023 Category: General Medicine Authors: Tags: Conditions Obesity Source Type: blogs

Cellular Senescence in Type 2 Diabetes
It has been a few years since researchers suggested a role for senescent cells in mediating the damage done by excess fat tissue in the context of type 2 diabetes. Senescent cells accumulate with age, but accumulate significantly faster in people who are meaningfully overweight or obese. The inflammatory signaling produced by lingering senescent cells is disruptive of tissue structure and function throughout the body, and that includes problems in the insulin-generating regions of the pancreas that take place in diabetes patients. Interestingly, senescent cells may also be important in type 1 diabetes, a completely differe...
Source: Fight Aging! - March 20, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, March 20th 2023
This study also provides the potential for de novo generation of complex organs in vivo. T Cells May Play a Role in the Brain Inflammation Characteristic of Neurodegenerative Conditions https://www.fightaging.org/archives/2023/03/t-cells-may-play-a-role-in-the-brain-inflammation-characteristic-of-neurodegenerative-conditions/ Alzheimer's disease, and other forms of neurodegenerative condition, are characterized by chronic inflammation in brain tissue. Unresolved inflammatory signaling is disruptive of tissue structure and function. Here, researchers provide evidence for T cells to become involved in thi...
Source: Fight Aging! - March 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Insulin Metabolism May Affect Life Span via Effects on Innate Immune Function
Insulin metabolism is one of the better studied areas of biochemistry in connection with aging, and one of the earliest areas of focus for the aging research community. Dysfunction of insulin metabolism, meaning loss of insulin sensitivity, is characteristic of obesity and the slide into type 2 diabetes, and the manifestations of diabetes in some ways resemble accelerated aging. While one should not consider high levels of a single form of dysfunction to be accelerated aging, since normal aging is a specific mix of various forms of damage and dysfunction, it can be worth bearing in mind that there are mechanistic overlaps ...
Source: Fight Aging! - March 17, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Lifestyle change: the forgotten solution in health care
Lifestyle change is a first-line treatment for many diseases. However, change is inherently challenging. This difficulty is exacerbated by a lack of lifestyle change “breakthroughs,” whereas multiple pharmaceutical breakthroughs have occurred over the years. Thus, pharmaceutical interventions are emphasized. For example, the American Academy of Pediatrics issued new obesity treatment guidelines that included medications and Read more… Lifestyle change: the forgotten solution in health care originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 15, 2023 Category: General Medicine Authors: Tags: Conditions Primary Care Source Type: blogs

Breaking the cycle of childhood obesity
Every specialty has its burden, and pediatric endocrinology’s is obesity. Primary care providers refer because they or the child’s parents suspect the cause is hormonal. It almost never is. The overly adipose child invariably has, using older terminology, exogenous obesity. Traditionally, this has implied excessive calorie intake and inadequate expenditure (the “overactive fork and underactive Read more… Breaking the cycle of childhood obesity originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 14, 2023 Category: General Medicine Authors: Tags: Conditions Obesity Pediatrics Source Type: blogs

WeightWatchers to Acquire Sequence, a Digital Health Platform for Clinical Weight Management
First-of-Its-Kind Weight Management Solution to Pair WeightWatchers Proven Nutrition and Behavioral Science with the Sequence Clinical Platform WW International, Inc. (WeightWatchers, WW, or the Company) has entered into a definitive agreement to acquire Weekend Health, Inc., d/b/a Sequence, a subscription telehealth platform offering access to healthcare providers specializing in chronic weight management. Sequence seamlessly integrates the patient and clinician experience for ongoing clinical care and medication management, while providing high-touch support in navigating the insurance approval process. Obesity is a comp...
Source: EMR and HIPAA - March 14, 2023 Category: Information Technology Authors: Healthcare IT News Tags: Health IT Company Healthcare IT Clinical Intervention d/b/a Sequence Dr. Gary Foster Health IT Acquisitions Healthcare M&A obesity Rémi Cossart Sima Sistani Telehealth Weekend Health Weekend Health Inc. Weight Management Weigh Source Type: blogs

The holistic solution to obesity: Addressing mind, body, and behaviors for lasting weight loss
Ozempic, Wegovy, Mounjaro. These names have entered our common parlance within the last year via news articles, television stories, and celebrity exposes. Everyone from Hollywood to your neighbor seems to be on medication for weight loss or trying to find a way to access one via their medical provider, from primary care physicians to dermatologists. Read more… The holistic solution to obesity: Addressing mind, body, and behaviors for lasting weight loss originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 13, 2023 Category: General Medicine Authors: Tags: Conditions Obesity Source Type: blogs

Bonus Features – March 12, 2023 – 87% of docs used telemedicine in 2021, 65% of healthcare orgs collect more trivial data once they adopt the cloud, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. News Three Democratic Senators have introduced legislation to expand protections for Americans’ personal health data privacy. Sponsored by Amy Klobuchar (Minnesota), Elizabeth Warren (Massachusetts), and Mazie Hirono (Hawaii),...
Source: EMR and HIPAA - March 12, 2023 Category: Information Technology Authors: Brian Eastwood Tags: C-Suite Leadership Healthcare IT Accenture ACCESS Family Care Amy Klobuchar Anne Walker ATA Atropos Health Avi Mukherjee Blancco Technology Group Bright.md Cardinal Health CLEAR Converged Outreach COTA CRIP Crossroads Treat Source Type: blogs

Semaglutide – the “ skinny jab ”
TL:DR – Semaglutide is known to US celebrities as the “skinny jab” and has apparently been the subject of a weight-loss craze. It has now been approved in the UK for weight-loss in the clinically obese. Semaglutide is a pharmaceutical that can help control the symptoms of Type 2 diabetes for which it was first used. The nickname, the “skinny jab” comes from the drug’s activity as an appetite suppressant used in helping overweight people and the obese reduce their body weight. It is sold under the brand names Ozempic, Wegovy and Rybelsus and was originally developed by Novo Nordisk in 20...
Source: David Bradley Sciencebase - Songs, Snaps, Science - March 8, 2023 Category: Science Authors: David Bradley Tags: Health and Medicine Obesity Source Type: blogs