Fight Aging! Newsletter, January 22nd 2024
In this study, we found that DMC reduced the SASP level in senescent cells. Furthermore, senescent cells enter irreversible cell cycle arrest, which involves the activation of p53/p21 and Rb/p16. In this study we found that the expression levels of p21 and p16 were decreased after DMC treatment. The downregulation of p21 may be attributed to the decrease of p53. In this study, we found that the mRNA level of p53 was reduced after DMC treatment.
Ferroptosis is an iron-dependent cell death process, which is accompanied by iron accumulation. Our previous study reported an important role of FECH, an enzyme inserts ferro...
Source: Fight Aging! - January 21, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Novel Proteomic Aging Clock
By now there are most likely dozens of published aging clocks constructed from various omics databases. The proliferation of new clocks isn't helping to solve the fundamental problem with this approach to assessing biological age, which is that the predicted biological age produced by a clock isn't actionable, as no-one yet understands how the clocks relate to causative processes of aging. Thus factions within the research community are arguing for standardization to a single clock, followed by focused effort on understand how those clock measurements relate to underlying processes of aging.
Using a large proteomi...
Source: Fight Aging! - January 19, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
2024 Intentions
After nearly 20 years of blogging about self-development, this year I intend to contribute mainly through video instead of writing, which is a big change for me. I want this to be the first year that I publish more new videos than articles. I’ll still share new YouTube videos via my blog, but if you’re into YouTube, you may want to subscribe to my channel there.
In this first new video of 2024, I also reveal many other intentions; recent decisions; and updates about psychedelics explorations, Conscious Growth Club, the new Engage course, and more. I recorded this one mainly for long-term members of this comm...
Source: Steve Pavlina's Personal Development Blog - January 16, 2024 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Creating Reality Values Video Source Type: blogs
What ’ s in a name?
What names we give the flora and fauna. Names are critical for scientific discourse and general conversation alike. They can be weird and wonderful, informative, confusing, hilarious even, and sometimes baffling. While common, or vernacular, names vary wildly, science, of course, has a relatively standardised method of naming living things. The common format, which is often colloquially known as the Latin name, is to have the species in a genus, a family group, and then to follow that genus name with the species name.
For example, in the UK, we might talk of the Snowdrop, or the Common Snowdrop. This delicate plant with wh...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 16, 2024 Category: Science Authors: David Bradley Tags: Biology Science Source Type: blogs
How AI and AIOps are Reshaping the Future of Healthcare IT
The following is a guest article by Scott Pross, VP of Technology at Monalytic, a SolarWinds Company
The future of healthcare will be powered by artificial intelligence (AI).
AI can enhance the speed and accuracy of diagnosis, book appointments, support clinical trials, reduce costs and errors, and improve cybersecurity posture. AI can also address the shortage of skilled healthcare workers – particularly in the field of IT operation. Indeed, a study by the Health Management Academy found that 47.5% of health systems currently use AI solutions to address workforce challenges and improve productivity, with the rest consid...
Source: EMR and HIPAA - January 16, 2024 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops AIOps Cybersecurity Health IT Monitoring Healthcare AI Monalytic Scott Pross SolarWinds Source Type: blogs
Anatomy of Trust: Promoting Integrity in A & P Education | Winter Shorts | TAPP 146
Episode 146 of The A&P Professor podcast is one of ourwinter shorts, where I replay interesting segments from previous episodes. In this one, we discuss the importance ofacademic integrity in the Anatomy& Physiology course. We emphasize the need to incorporatediscussions about integrity in the syllabus and course materials and sharereal-life examples of violations in the healthcare field. We highlight how dishonesty can haveserious consequences and discuss strategies for prevention, such as using multiple test versions and unique topics for papers/projects. Providingexamples of acceptable practices and discouraging...
Source: The A and P Professor - January 16, 2024 Category: Physiology Authors: Kevin Patton Source Type: blogs
Using our Journal Evaluation Tool to determine credibility of a journal
It’s been about seven years since we developed a tool (a downloadable rubric and explainer) to help our faculty determine the credibility of a journal. You can download the tool at https://digitalcommons.lmu.edu/librarian_pubs/40/ and read about the development of it at https://jlsc-pub.org/articles/abstract/10.7710/2162-3309.2250/. People have told us – often! – how they use the tool in their personal decision-making about where to publish, as well as sharing the tool in their classrooms and with friends. When we developed the tool, I hoped the set of decision criteria in it would be used to further the broader disc...
Source: Organization Monkey - January 14, 2024 Category: Databases & Libraries Authors: Marie Kennedy Tags: library OA publishers writing Source Type: blogs
New Book Sketches
One of my favorite things when writing children ' s books is when my wonderful and talented illustrator,Kyra Teis, takes my notes and creates the characters and illustrations for the picture book. It ' s so exciting to see my ideas come to life, and to have the beginning artwork take shape. My next book will focus on jealousy in children in late 2024. Can ' t wait to share more. (Source: Dr. Deborah Serani)
Source: Dr. Deborah Serani - January 12, 2024 Category: Psychiatry & Psychology Tags: books children jealousy libraries parenting psychology read-aloud visits self help booksteachers wellbeing Source Type: blogs
Drop some positivity in the next article you peer review
We recently received feedback on an article we submitted for publication, and I was delighted that the comments we received were all entirely positively toned and productive. The reviewer(s) brought up some issues that we could act on in the revision, and we were happy to make those changes. Overall, it was a good vibes review experience. Upon reflection, it was nice because of the attitude of the reviewer’s comments.
Over the years I’ve become accustomed to critical reviews that are couched in either neutral or negative language. That’s fine, I can take a critical review, and I know reviewers are likely just trying ...
Source: Organization Monkey - January 5, 2024 Category: Databases & Libraries Authors: Marie Kennedy Tags: writing Source Type: blogs
What's new in midwifery - 4th January 2024 (Happy New Year!)
Some things that might be useful to know aboutPerinatal bereavementSANDS Listening Project, learning from the experiences of Black and Asian bereaved parents (PDF)Infant feedingBreastfeeding and once-daily small-volume formula supplementation to prevent infant growth impairment, (open access research article)Perinatal mental healthPerinatal mental health conditions, SIGN (Scottish Intercollegiate Guideline Network) Guideline 169 DeliveryPerinatal morbidity among women with a previous caesarean delivery (PRISMA trial): a cluster-randomised trial, link to PubMed record (subscription needed to read the article...
Source: Browsing - January 4, 2024 Category: Databases & Libraries Tags: midwifery Source Type: blogs
What ’ s Special About AI Risks and Remedies in Health Care?
This article looks at what’s special about AI in health care, and some ways to address its needs. For this article, I spoke just to lawyers, because we’ve heard plenty from the technologists about AI’s potential and what they’re doing to minimize risk. The perspective of attorneys with an expertise in health care is illuminating.
An anthology from STAT also contains some relevant analyses and case studies.
Liability and Licensing
Are clinicians facing the risk of lawsuits if they heed the advice of AI engines? Where do the new systems differ from older forms of clinical decision support—or the s...
Source: EMR and HIPAA - December 29, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Clinical Health IT Company Healthcare IT Hospital - Health System Regulations Security and Privacy Bard Berger Singerman LLP ChatGPT Erica Kraus FDA FDA AI Regulations Google Bard Healthcare AI Healthcare Source Type: blogs
LexisNexis Risk Solutions Takes Social Determinants of Health to New Heights
During the past decade, finally, health care is starting to deal in a structured, measurable manner with the life factors and environments that play the biggest role in their patients’ health. A recent offering from LexisNexis Risk Solutions promises to greatly expand access to this data, called social determinants of health (SDoH), for payers, clinicians, public health agencies, pharma companies, and other researchers.
The company LexisNexis Risk Solutions is almost synonymous with the data banks of consumer data that financial firms and other businesses consult for identity verification and outreach. The company...
Source: EMR and HIPAA - December 27, 2023 Category: Information Technology Authors: Andy Oram Tags: Analytics/Big Data C-Suite Leadership Health IT Company Healthcare IT Hospital - Health System Regulations Diana Zuskov Health Data Diversity Health Equity Healthcare AI Bias LexisNexis LexisNexis Risk Solutions McKenzie Funk Pub Source Type: blogs
What's new in midwifery - 19th December 2023
First of all, season ' s greetings and best wishes for a peaceful and happy 2024.Some new things you might find useful.Royal CollegesRoyal College of Nursing resource for nursing and midwifery practice about female genital mutilation (PDF). There is alsothis supplement about sexual health care (also PDF)Royal College of Obstetricians and Gynaecologists Good Practice Paper no. 17, Maternity triage (PDF)New publications from MBRRACEPerinatal confidential enquiry, A comparison of the care of Black and White women who have experienced a stillbirth or neonatal death, published December 2023 (PDF)Perina...
Source: Browsing - December 19, 2023 Category: Databases & Libraries Tags: midwifery Source Type: blogs
Fight Aging! Newsletter, December 18th 2023
In conclusion, given the relative safety and the favourable effects of aspirin, its use in cancer seems justified, and ethical implications of this imply that cancer patients should be informed of the present evidence and encouraged to raise the topic with their healthcare team.
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Aged Transplant Organs Cause Harm to Younger Recipients
https://www.fightaging.org/archives/2023/12/aged-transplant-organs-cause-harm-to-younger-recipients/
Old tissues are dysfunctional in ways that young tissues are not. This has always been known in the context of organ transplants, but absent me...
Source: Fight Aging! - December 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Weekly Roundup – December 16, 2023
Welcome to our Healthcare IT Today Weekly Roundup. Each week, we’ll be providing a look back at the articles we posted and why they’re important to the healthcare IT community. We hope this gives you a chance to catch up on anything you may have missed during the week.
Big News From the ONC Meeting: QHINs, TEFCA, and HTI-1. This week in DC, ONC announced the first five QHINs to complete the TEFCA onboarding process. In addition, the agency released the HTI-1 final rule, with important provisions covering algorithm transparency in certified health IT and updates to information blocking requirements. Read more…
Unp...
Source: EMR and HIPAA - December 16, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Healthcare IT Today Weekly Roundup Source Type: blogs
