First degree AV block, sinus pause, QT prolongation on ECG
(Source: Cardiophile MD)
Source: Cardiophile MD - February 4, 2024 Category: Cardiology Authors: Johnson Francis Tags: ECG / Electrophysiology ECG Library Source Type: blogs
Wellens syndrome and more on ECG
(Source: Cardiophile MD)
Source: Cardiophile MD - February 4, 2024 Category: Cardiology Authors: Johnson Francis Tags: ECG / Electrophysiology ECG Library Source Type: blogs
What are the ECG Changes in Intracranial Hemorrhage?
(Source: Cardiophile MD)
Source: Cardiophile MD - February 3, 2024 Category: Cardiology Authors: Johnson Francis Tags: ECG / Electrophysiology ECG Library Source Type: blogs
GRCr8: A new rat reference assembly is released!
GRCr8 (GCA_036323735.1), the latest version of the rat reference genome assembly, is now available. GRCr8 is an evolution of mRatBN7.2 (GCA_015227675.2), the Vertebrate Genomes Project-generated rat assembly that was the first reference for this species to be adopted by the GRC for stewardship. mRatBN7.2 was an assembly of a Brown Norway (BN) male rat from the same colony at the Medical College of Wisconsin that supplied the female rat used in the 2004 RGSC_v3.4 assembly (AABR00000000.3/GCF_000001895.1). While the assembly of mRatBN7.2 was a substantial improvement over prior versions (https://pubmed.ncbi.nlm.nih.gov/37214...
Source: GenomeRef - February 2, 2024 Category: Genetics & Stem Cells Source Type: blogs
Enhancing Payment Integrity in Healthcare through Pre-Payment Reviews
The following is a guest article by Tom Magnotta, COO & President at Apixio
Albert Einstein famously said, “Whoever is careless with the truth in small matters cannot be trusted with important matters.” This quote lies at the heart of integrity, a powerful concept that applies equally critically in the healthcare payments environment as it does in daily life. Payment integrity is essential for ensuring financial accuracy, maintaining compliance with regulations, optimizing the healthcare delivery system, and removing administrative waste, which impacts the focus on patient care and quality outcomes. It also plays...
Source: EMR and HIPAA - February 2, 2024 Category: Information Technology Authors: Guest Author Tags: Administration AI/Machine Learning Ambulatory Health IT Company Healthcare IT Hospital - Health System Revenue Cycle Management Apixio Healthcare Claims Healthcare Costs Insurance Payments Payment Integrity Pre-Payment Model RCM Source Type: blogs
Calling out the bullshit
Conclusions and Relevance Results of this study indicated that research and development
investments did not explain the variation in list prices for the 60
drugs in this sample. Drug companies should make further data available
to support their claims that high drug prices are needed to recover
research and development investments, if they are to continue to use
this argument to justify high prices. In case you don ' t know much about statistics, this is as zero of a correlation as you will ever get. I mean no association at all, zip, zilch, nada. And I might add that the basic research to identify biol...
Source: Stayin' Alive - January 26, 2024 Category: American Health Source Type: blogs
The Business Case for a Biosimilar Company to Bring a Copy of Levemir to Market
My readers may recall that in November 2023, I blogged that Novo Nordisk announced it plans to retire (stop making) its first " Lantus killer " known as Levemir (insulin detemir injection) in the U.S. in 2024 (catch my post at https://blog.sstrumello.com/2023/11/novo-nordisk-to-discontinue-levemir-in.html for more). At the time I learned of the announcement, I was on vacation in Amsterdam, so I just made a note of the development and blogged about it a few weeks later upon my return.Like other patients my age, I have endured the company ' s previous insulin " retirements " . Novo Nordisk ' s time-frame for withdr...
Source: Scott's Web Log - January 25, 2024 Category: Endocrinology Tags: 2024 Biosimilar Levemir Novo Nordisk PBM Source Type: blogs
7 Things To Expect From AI In Healthcare This Year
The past year was all about artificial intelligence, with a particular focus on its integration into healthcare in our universe. At The Medical Futurist, we have extensively explored how AI is reshaping the healthcare landscape, outlining what to expect and how to prepare for these transformative changes.
As we move into 2024, it’s time to continue our forward-looking journey. This year promises to be a blend of consolidation and revolution. Some trends we’ve previously identified are beginning to solidify and integrate into the fabric of healthcare systems, while others are just starting to unfold.
In th...
Source: The Medical Futurist - January 25, 2024 Category: Information Technology Authors: Andrea Koncz Tags: TMF AI AI in medicine artificial intelligence artificial intelligence in healthcare Source Type: blogs
Drug prices continued: Innovation?
Pharmaceutical manufacturers claim that they need patent protection and marketing exclusivity so they can charge high prices to recoup the costs of drug development and clinical trials. There are a few things wrong with this argument, but they add up to the general fact that the system does not serve the public interest. Drug companies care about one thing only, that is profit. And the pursuit of profit does not serve the interests of public health or social welfare.One obvious mismatch between the goal of public health and the goal of profit is that a relatively cheap drug that you can take once or for a week or so, that ...
Source: Stayin' Alive - January 23, 2024 Category: American Health Source Type: blogs
Data discovery: seasonal speed
Just writing this one quickly as it’s been hanging around my browser tabs for weeks…
I wrote Taking steps (in XML) almost 7 years ago and once in a while, I still grab Apple Health data from my phone and play around with it in R for a few minutes. Sometimes, curve fitting to a cloud of points generates a surprise.
library(tidyverse)
library(xml2)
theme_set(theme_bw())
health_data <- read_xml("~/Documents/apple_health_export/export.xml")
ws <- xml_find_all(health_data, ".//Record[@type='HKQuantityTypeIdentifierWalkingSpeed']") %>%
map(xml_attrs) %>%
map_df(as.li...
Source: What You're Doing Is Rather Desperate - January 23, 2024 Category: Bioinformatics Authors: nsaunders Tags: R statistics health rstats walking xml Source Type: blogs
Fight Aging! Newsletter, January 22nd 2024
In this study, we found that DMC reduced the SASP level in senescent cells. Furthermore, senescent cells enter irreversible cell cycle arrest, which involves the activation of p53/p21 and Rb/p16. In this study we found that the expression levels of p21 and p16 were decreased after DMC treatment. The downregulation of p21 may be attributed to the decrease of p53. In this study, we found that the mRNA level of p53 was reduced after DMC treatment.
Ferroptosis is an iron-dependent cell death process, which is accompanied by iron accumulation. Our previous study reported an important role of FECH, an enzyme inserts ferro...
Source: Fight Aging! - January 21, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Novel Proteomic Aging Clock
By now there are most likely dozens of published aging clocks constructed from various omics databases. The proliferation of new clocks isn't helping to solve the fundamental problem with this approach to assessing biological age, which is that the predicted biological age produced by a clock isn't actionable, as no-one yet understands how the clocks relate to causative processes of aging. Thus factions within the research community are arguing for standardization to a single clock, followed by focused effort on understand how those clock measurements relate to underlying processes of aging.
Using a large proteomi...
Source: Fight Aging! - January 19, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
2024 Intentions
After nearly 20 years of blogging about self-development, this year I intend to contribute mainly through video instead of writing, which is a big change for me. I want this to be the first year that I publish more new videos than articles. I’ll still share new YouTube videos via my blog, but if you’re into YouTube, you may want to subscribe to my channel there.
In this first new video of 2024, I also reveal many other intentions; recent decisions; and updates about psychedelics explorations, Conscious Growth Club, the new Engage course, and more. I recorded this one mainly for long-term members of this comm...
Source: Steve Pavlina's Personal Development Blog - January 16, 2024 Category: Psychiatry & Psychology Authors: Steve Pavlina Tags: Creating Reality Values Video Source Type: blogs
What ’ s in a name?
What names we give the flora and fauna. Names are critical for scientific discourse and general conversation alike. They can be weird and wonderful, informative, confusing, hilarious even, and sometimes baffling. While common, or vernacular, names vary wildly, science, of course, has a relatively standardised method of naming living things. The common format, which is often colloquially known as the Latin name, is to have the species in a genus, a family group, and then to follow that genus name with the species name.
For example, in the UK, we might talk of the Snowdrop, or the Common Snowdrop. This delicate plant with wh...
Source: David Bradley Sciencebase - Songs, Snaps, Science - January 16, 2024 Category: Science Authors: David Bradley Tags: Biology Science Source Type: blogs
How AI and AIOps are Reshaping the Future of Healthcare IT
The following is a guest article by Scott Pross, VP of Technology at Monalytic, a SolarWinds Company
The future of healthcare will be powered by artificial intelligence (AI).
AI can enhance the speed and accuracy of diagnosis, book appointments, support clinical trials, reduce costs and errors, and improve cybersecurity posture. AI can also address the shortage of skilled healthcare workers – particularly in the field of IT operation. Indeed, a study by the Health Management Academy found that 47.5% of health systems currently use AI solutions to address workforce challenges and improve productivity, with the rest consid...
Source: EMR and HIPAA - January 16, 2024 Category: Information Technology Authors: Guest Author Tags: AI/Machine Learning Health IT Company Healthcare IT Hospital - Health System IT Infrastructure and Dev Ops AIOps Cybersecurity Health IT Monitoring Healthcare AI Monalytic Scott Pross SolarWinds Source Type: blogs
