Side-by-side comparison of the two widely studied GRPR radiotracers, radiolabeled NeoB and RM2, in a preclinical setting
CONCLUSION: Based on these findings, we conclude that the in vivo tumor-targeting capability of radiolabeled NeoB and RM2 is similar. Additional studies are needed to determine whether the differences observed in physiological organ uptakes, i.e., the pancreas, kidneys, and blood, result in relevant differences in organ absorbed doses when the radiotracers are applied for therapeutic purposes.PMID:37584725 | DOI:10.1007/s00259-023-06364-4 (Source: Molecular Medicine)
Source: Molecular Medicine - August 16, 2023 Category: Molecular Biology Authors: T S T Damiana P Para ïso C de Ridder D Stuurman Y Seimbille S U Dalm Source Type: research
Undergraduate nursing students' knowledge and experience in infusion therapy and peripheral vascular acces
CONCLUSIONS: practical classes and execution of procedures in health services were predictors for a better knowledge about infusion therapy and vascular access by undergraduate nursing students.PMID:37556688 | DOI:10.1590/0034-7167-2022-0219 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - August 9, 2023 Category: Nursing Authors: Jaciara Tiago Antunes Alvarenga Adriana Cristina Nicolussi Aline Maria Pereira Cruz Ramos Lucas Fernando Antunes Gomes Damiana Aparecida Trindade Monteiro Silmara Elaine Malaguti Toffano Source Type: research
Undergraduate nursing students' knowledge and experience in infusion therapy and peripheral vascular acces
CONCLUSIONS: practical classes and execution of procedures in health services were predictors for a better knowledge about infusion therapy and vascular access by undergraduate nursing students.PMID:37556688 | DOI:10.1590/0034-7167-2022-0219 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - August 9, 2023 Category: Nursing Authors: Jaciara Tiago Antunes Alvarenga Adriana Cristina Nicolussi Aline Maria Pereira Cruz Ramos Lucas Fernando Antunes Gomes Damiana Aparecida Trindade Monteiro Silmara Elaine Malaguti Toffano Source Type: research
Undergraduate nursing students' knowledge and experience in infusion therapy and peripheral vascular acces
CONCLUSIONS: practical classes and execution of procedures in health services were predictors for a better knowledge about infusion therapy and vascular access by undergraduate nursing students.PMID:37556688 | PMC:PMC10405391 | DOI:10.1590/0034-7167-2022-0219 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - August 9, 2023 Category: Nursing Authors: Jaciara Tiago Antunes Alvarenga Adriana Cristina Nicolussi Aline Maria Pereira Cruz Ramos Lucas Fernando Antunes Gomes Damiana Aparecida Trindade Monteiro Silmara Elaine Malaguti Toffano Source Type: research
Undergraduate nursing students' knowledge and experience in infusion therapy and peripheral vascular acces
CONCLUSIONS: practical classes and execution of procedures in health services were predictors for a better knowledge about infusion therapy and vascular access by undergraduate nursing students.PMID:37556688 | PMC:PMC10405391 | DOI:10.1590/0034-7167-2022-0219 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - August 9, 2023 Category: Nursing Authors: Jaciara Tiago Antunes Alvarenga Adriana Cristina Nicolussi Aline Maria Pereira Cruz Ramos Lucas Fernando Antunes Gomes Damiana Aparecida Trindade Monteiro Silmara Elaine Malaguti Toffano Source Type: research
Undergraduate nursing students' knowledge and experience in infusion therapy and peripheral vascular acces
CONCLUSIONS: practical classes and execution of procedures in health services were predictors for a better knowledge about infusion therapy and vascular access by undergraduate nursing students.PMID:37556688 | PMC:PMC10405391 | DOI:10.1590/0034-7167-2022-0219 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - August 9, 2023 Category: Nursing Authors: Jaciara Tiago Antunes Alvarenga Adriana Cristina Nicolussi Aline Maria Pereira Cruz Ramos Lucas Fernando Antunes Gomes Damiana Aparecida Trindade Monteiro Silmara Elaine Malaguti Toffano Source Type: research
Undergraduate nursing students' knowledge and experience in infusion therapy and peripheral vascular acces
CONCLUSIONS: practical classes and execution of procedures in health services were predictors for a better knowledge about infusion therapy and vascular access by undergraduate nursing students.PMID:37556688 | PMC:PMC10405391 | DOI:10.1590/0034-7167-2022-0219 (Source: Revista Brasileira de Enfermagem)
Source: Revista Brasileira de Enfermagem - August 9, 2023 Category: Nursing Authors: Jaciara Tiago Antunes Alvarenga Adriana Cristina Nicolussi Aline Maria Pereira Cruz Ramos Lucas Fernando Antunes Gomes Damiana Aparecida Trindade Monteiro Silmara Elaine Malaguti Toffano Source Type: research
Physicochemical Study, Chemical Profiling and Molecular Docking Study for Standardisation of the Homoeopathic Drug Damiana
Conclusion Our study provides pharmacopoeial standards which show that even for exotic plants the quality of mother tinctures from Indian and international companies is similar. [...] Thieme Medical and Scientific Publishers Pvt. Ltd. A-12, 2nd Floor, Sector 2, Noida-201301 UP, IndiaArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Homoeopathic Links)
Source: Homoeopathic Links - August 7, 2023 Category: Complementary Medicine Authors: Biswas, Bibaswan Maity, Satyajit Bhar, Kaushik Sett, Sudeshna Kumar, G.V. Narasimha Tags: Original Article Source Type: research
Cancers, Vol. 15, Pages 3599: The Multiple Faces of the MRN Complex: Roles in Medulloblastoma and Beyond
useppe Giannini
Hypomorphic mutations in MRN complex genes are frequently found in cancer, supporting their role as oncosuppressors. However, unlike canonical oncosuppressors, MRN proteins are often overexpressed in tumor tissues, where they actively work to counteract DSBs induced by both oncogene-dependent RS and radio-chemotherapy. Moreover, at the same time, MRN genes are also essential genes, since the constitutive KO of each component leads to embryonic lethality. Therefore, even though it is paradoxical, MRN genes may work as oncosuppressive, oncopromoting, and essential genes. In this review, we discussed how a...
Source: Cancers - July 13, 2023 Category: Cancer & Oncology Authors: Marialaura Petroni Veronica La Monica Francesca Fabretti Mariaconcetta Augusto Damiana Battaglini Francesca Polonara Stefano Di Giulio Giuseppe Giannini Tags: Review Source Type: research
Ketogenic diet ameliorates autism spectrum disorders-like behaviors via reduced inflammatory factors and microbiota remodeling in BTBR mice
Exp Neurol. 2023 May 4:114432. doi: 10.1016/j.expneurol.2023.114432. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is increasing, but its complete etiology is still lacking. Recently, application of ketogenic diet (KD) has shown to reduce abnormal behaviors while improving psychological/sociological status in neurodegenerative diseases. However, KD role on ASD and underlying mechanism remains unknown. In this work, KD administered to BTBR and C57BL/6 J (C57) mice reduced social deficits (p = 0.002), repetitive behaviors (p < 0.001) and memory impairments (p = 0.001) in BTBR. Behavioral effects were relate...
Source: Experimental Neurology - May 6, 2023 Category: Neurology Authors: Ilaria Olivito Ennio Avolio Damiana Minervini Teresa Soda Carmine Rocca Tommaso Angelone Francesco Salvatore Iaquinta Dina Bellizzi Francesco De Rango Rosalinda Bruno Loredana De Bartolo Raffaella Al ò Marcello Canonaco Rosa Maria Facciolo Source Type: research
Ketogenic diet ameliorates autism spectrum disorders-like behaviors via reduced inflammatory factors and microbiota remodeling in BTBR mice
Exp Neurol. 2023 May 4:114432. doi: 10.1016/j.expneurol.2023.114432. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is increasing, but its complete etiology is still lacking. Recently, application of ketogenic diet (KD) has shown to reduce abnormal behaviors while improving psychological/sociological status in neurodegenerative diseases. However, KD role on ASD and underlying mechanism remains unknown. In this work, KD administered to BTBR and C57BL/6 J (C57) mice reduced social deficits (p = 0.002), repetitive behaviors (p < 0.001) and memory impairments (p = 0.001) in BTBR. Behavioral effects were relate...
Source: Experimental Neurology - May 6, 2023 Category: Neurology Authors: Ilaria Olivito Ennio Avolio Damiana Minervini Teresa Soda Carmine Rocca Tommaso Angelone Francesco Salvatore Iaquinta Dina Bellizzi Francesco De Rango Rosalinda Bruno Loredana De Bartolo Raffaella Al ò Marcello Canonaco Rosa Maria Facciolo Source Type: research
PE, or not PE, that is the question: the case of overlooked Lyso-N-acyl-phosphatidylethanolamines
CONCLUSIONS: Overall, our methodology demonstrates to be a robust approach to recognising L-NAPE in complex samples. L-NAPE 18:2-N-18:2, 18:2-N-18:3, 18:3-N-18:2, and 18:2-N-18:1 were the prevailing compounds in the analyzed tomato samples, accounting for more than 90%. In summary, a reliable method for identifying L-NAPE in complex samples is described. The proposed method could prevent overlooking L-NAPE and overestimating isomeric PE species in future lipid analyses.PMID:37117037 | DOI:10.1002/rcm.9527 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - April 28, 2023 Category: Chemistry Authors: Giovanni Ventura Cosima Damiana Calvano Mariachiara Bianco Andrea Castellaneta Ilario Losito Tommaso R I Cataldi Source Type: research
PE, or not PE, that is the question: the case of overlooked Lyso-N-acyl-phosphatidylethanolamines
CONCLUSIONS: Overall, our methodology demonstrates to be a robust approach to recognising L-NAPE in complex samples. L-NAPE 18:2-N-18:2, 18:2-N-18:3, 18:3-N-18:2, and 18:2-N-18:1 were the prevailing compounds in the analyzed tomato samples, accounting for more than 90%. In summary, a reliable method for identifying L-NAPE in complex samples is described. The proposed method could prevent overlooking L-NAPE and overestimating isomeric PE species in future lipid analyses.PMID:37117037 | DOI:10.1002/rcm.9527 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - April 28, 2023 Category: Chemistry Authors: Giovanni Ventura Cosima Damiana Calvano Mariachiara Bianco Andrea Castellaneta Ilario Losito Tommaso R I Cataldi Source Type: research
PE, or not PE, that is the question: the case of overlooked Lyso-N-acyl-phosphatidylethanolamines
CONCLUSIONS: Overall, our methodology demonstrates to be a robust approach to recognising L-NAPE in complex samples. L-NAPE 18:2-N-18:2, 18:2-N-18:3, 18:3-N-18:2, and 18:2-N-18:1 were the prevailing compounds in the analyzed tomato samples, accounting for more than 90%. In summary, a reliable method for identifying L-NAPE in complex samples is described. The proposed method could prevent overlooking L-NAPE and overestimating isomeric PE species in future lipid analyses.PMID:37117037 | DOI:10.1002/rcm.9527 (Source: Rapid Communications in Mass Spectrometry : RCM)
Source: Rapid Communications in Mass Spectrometry : RCM - April 28, 2023 Category: Chemistry Authors: Giovanni Ventura Cosima Damiana Calvano Mariachiara Bianco Andrea Castellaneta Ilario Losito Tommaso R I Cataldi Source Type: research
Exploring different high-capacity tools and extraction modes to characterize the aroma of brewed coffee
Anal Bioanal Chem. 2023 Apr 12. doi: 10.1007/s00216-023-04654-2. Online ahead of print.ABSTRACTIn the present work, the potential benefit of using multi-cumulative trapping headspace extraction was explored by comparing the results using solid-phase microextraction (SPME) coated with divinylbenzene/carboxen/polydimethylsiloxane and a probe-like tool coated with polydimethylsiloxane. The efficiency of a single 30-min extraction, already explored in previous work, was compared with that of multiple shorter extractions. We evaluated three different conditions, i.e., three repeated extractions for 10 min each from different sa...
Source: Analytical and Bioanalytical Chemistry - April 11, 2023 Category: Chemistry Authors: Damien Eggermont Natasha Damiana Spadafora Juan Aspromonte Roc ío Pellegrino Giorgia Purcaro Source Type: research
