Association of Neutrophil –Lymphocyte Ratio with Clinical Outcomes in Patients with Cystic Fibrosis
(Source: Indian Journal of Pediatrics)
Source: Indian Journal of Pediatrics - April 1, 2024 Category: Pediatrics Source Type: research
Outcomes of Combined Liver-Lung Transplant in Pediatric Patients with Cystic Fibrosis: An ISHLT Study
This study aims to analyze pre-transplant predictors and post-transplant outcomes of ConLi-LTx and lung transplant (LTx) only recipients. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , B. Langlais, B. Aqel, J. D'Cunha, P. Reck dos Santos Source Type: research
Assessing the Relationship Between Pre-Operative Opioid Use and Outcomes of Patients with Cystic Fibrosis Undergoing Lung Transplantation
Purpose: Pain syndromes are well characterized in patients with cystic fibrosis (CF) with up to 53% requiring opioid use. Recent evidence suggests that preoperative opioid use is associated with higher complication rates and worse survival outcomes for patients undergoing lung transplantation (LT) however this has not been well characterized among patients with CF undergoing LT who might require longer and higher opioid dosing compared to patients with other indications for LT. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J.M. Ruck, J.S. Ha, E. Bush, C. Merlo Source Type: research
Successful NTM Eradication and Lung Transplantation in Pediatric CF Patients
We present two pediatric cystic fibrosis (CF) patients with MABSC lung disease who underwent successful lung transplantation without NTM recurrence. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , C. Burton, O.G. Vanderkooi, M. McKinney, D. Lien, N. Avdimiretz Source Type: research
Paediatric Lung Transplantation for Childhood Interstitial Lung Disease Shows Favorable Outcome Compared with LuTx for Cystic Fibrosis or Pulmonary Hypertension
Purpose: Childhood interstitial lung disease (ChILD) is an umbrella term for more than 200 different rare diseases with a significant morbidity and mortality. Lung transplantation (LuTx) is an established treatment option for ChILD in patients with endstage lung disease. There is limited data on the indications and outcomes following LuTx in ChILD. The aim of this study is to evaluate the long term outcome in ChILD-patients following LuTx and its possible interrelation with the type and severity of the underlying disease. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , F. L änger, F. Ius, C. Müller, K. Schütz, D. Bobylev, J. Salman, N. Schwerk, J. Carlens Source Type: research
Trends in Pediatric Lung Transplantation Following the Height of the COVID-19 Pandemic
Purpose: The landscape of diagnostic indications for lung transplantation (LTX) in children is changing. We previously showed a reduction in pediatric LTX for cystic fibrosis (CF) in the U.S. The most notable attrition was in 2020 at the height of the COVID-19 pandemic. With data previously only available through September 2021, it was unclear if this change would continue post-pandemic. Here, we provide an update on the trends in pediatric LTX in the U.S. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , C. Benden Source Type: research
Fat-Soluble Vitamin Levels in Supplemented versus Non-Supplemented Individuals with Cystic Fibrosis Following Lung Transplantation
Purpose: Cystic Fibrosis (CF) patients are routinely supplemented with fat soluble vitamins (FSV ’s). However, there is some signal that in patients with CF who receive a lung transplant (LT), levels can rise above reference range. Current guidelines recommend stopping combination FSV’s after LT. We sought to compare the effect of stopping FSV supplementation after LT in patients with CF co mpared to previous practice. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: B. Doyle, , T. Ronnie, D.F. Dilling Source Type: research
Right Single Lung Transplantation After Left Pneumonectomy
Introduction: Single lung transplantation (SLTX) following a remote contralateral pneumonectomy (PN) is a rare, yet life-saving procedure that requires strategic surgical planning because of mediastinal shifts, enlarged pleural cavity and anatomical changes in the bronchovascular structures.Case Report: A 34-year-old man with non-cystic fibrosis (CF) bronchiectasis underwent left PN 15 years prior to undergoing right SLTX. Prior to transplantation, he was hospitalized numerous times with respiratory failure and consequently developed infections with multi-drug resistant Pseudomonas and Achromobacter. (Source: The Journal o...
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , A. Mehta, K. McCurry, S. Alparslan Source Type: research
Recurrence of Bronchiectasis Following Living Donor Lobar Lung Transplantation (LDLLT)
We describe recurrence of bronchiectasis in a CF patient in only one of two lobe allografts. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , B. Keller Source Type: research
The Multicenter KOALA Study: The Effects of Kaftrio After Lung Transplantation in Cystic Fibrosis
Purpose: Historically, the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) modulator Kaftrio has been withheld from lung transplant (LTx) recipients with Cystic Fibrosis (CF) due to uncertainty regarding its efficacy, concerns about potential drug interactions and costs. The focus of Kaftrio therapy has been on pulmonary improvement instead of extrapulmonary benefits. However, considering the multi-systemic nature of CF, and the persistence of extrapulmonary symptoms after LTx, Kaftrio may also have potential relevant benefits for CF patients post-transplant. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , B. Luijk, M. Hellemons, K.A. Visser, C.M. Hansen, R. van der Meer, T. Gan, H. van der Vaart, O. Akkerman, W.N. Steenhuis, H.G. Heijerman, E.A. Verschuuren Source Type: research
Utilization of Pseudomonas Eradication Protocols Amongst Lung Transplant Centers
Purpose: Chronic airway colonization with Pseudomonas is associated with the development of chronic lung allograft dysfunction (CLAD) in lung transplant recipients (LTRs). Eradication efforts with inhaled and/or systemic antibiotics are common in the cystic fibrosis population. The aim of our survey is to understand current Pseudomonas eradication practices within the lung transplant population. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , K. Saharia, E. Heil, J. Baddley, R. Reed, M. Eberlein, K. Prakash Source Type: research
Mycotic Aortic Infection with Exophiala Dermatitidis in a Lung Transplant Patient with Cystic Fibrosis
We present a case of a patient who had lung transplantation for cystic fibrosis complicated by late invasive Exophiala dermatitidis infection. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: , J. Samuel, B. Ramesh, S. Clark, A. Fisher, G. Meachery, A. Nair, J. Lordan Source Type: research
The impact of switching to race-neutral reference equations on FEV1 percent predicted among people with cystic fibrosis,
Racial and ethnic disparities in health, shaped by implicit and overt racism, are pervasive and substantial. Societal structures such as health care, economic and legal systems, education and housing profoundly impact health [1 –3]. Experiences of racism, both direct and vicarious, also contribute to poorer health outcomes among minoritized individuals [4]. With the growing emphasis on improving health equity over the past two decades has come increased attention to the racist origins and racial biases in a range of clin ical tests [5], including spirometry [6], glomerular filtration rate [7] and pulse oximetry [8]. (Sou...
Source: Journal of Cystic Fibrosis - March 30, 2024 Category: Respiratory Medicine Authors: Margaret Rosenfeld, Elizabeth A. Cromwell, Michael S. Schechter, Clement Ren, Patrick A. Flume, Rhonda D. Szczesniak, Wayne J. Morgan, Raksha Jain Tags: Original Article Source Type: research
Retracted: Discovering Common Pathophysiological Processes between COVID-19 and Cystic Fibrosis by Differential Gene Expression Pattern Analysis
Biomed Res Int. 2024 Mar 20;2024:9789856. doi: 10.1155/2024/9789856. eCollection 2024.ABSTRACT[This retracts the article DOI: 10.1155/2022/8078259.].PMID:38550179 | PMC:PMC10973241 | DOI:10.1155/2024/9789856 (Source: Biomed Res)
Source: Biomed Res - March 29, 2024 Category: Research Authors: BioMed Research International Source Type: research
Retracted: Discovering Common Pathophysiological Processes between COVID-19 and Cystic Fibrosis by Differential Gene Expression Pattern Analysis
Biomed Res Int. 2024 Mar 20;2024:9789856. doi: 10.1155/2024/9789856. eCollection 2024.ABSTRACT[This retracts the article DOI: 10.1155/2022/8078259.].PMID:38550179 | PMC:PMC10973241 | DOI:10.1155/2024/9789856 (Source: Biomed Res)
Source: Biomed Res - March 29, 2024 Category: Research Authors: BioMed Research International Source Type: research
