Rate and predictors of insufficient sweat volume in very young infants after pilocarpine gel iontophoresis: prospective, population-based study
Conclusion
QNS rates fulfilled the requirements, but predictors differed from those recommended by the Cystic Fibrosis Foundations guidelines. (Source: Archives of Disease in Childhood)
Source: Archives of Disease in Childhood - March 19, 2024 Category: Pediatrics Authors: Camargos, P., Bedran, R. M., Alvim, C. G., Sader, O. G. Tags: Original research Source Type: research
Clinical outcomes of functional endoscopic sinus surgery in cystic fibrosis patients - a single centre experience
CONCLUSIONS: There was a demonstrated clinical and symptomatic benefit of ESS in CF patients in this study. Stricter guidelines for indications for ESS need to be established with regards to CF patients who will undergo ESS in the future.PMID:38497762 | DOI:10.4193/Rhin23.057 (Source: Rhinology)
Source: Rhinology - March 18, 2024 Category: ENT & OMF Authors: Y Devabalan R Towning J Magill H Saleh C Rennie Source Type: research
Intracellular < em > Pseudomonas aeruginosa < /em > : An Overlooked Reservoir in the Lungs of People with Cystic Fibrosis?
Am J Respir Crit Care Med. 2024 Mar 18. doi: 10.1164/rccm.202402-0388ED. Online ahead of print.NO ABSTRACTPMID:38498854 | DOI:10.1164/rccm.202402-0388ED (Source: American Journal of Respiratory and Critical Care Medicine)
Source: American Journal of Respiratory and Critical Care Medicine - March 18, 2024 Category: Respiratory Medicine Authors: Aur élie Crabbé Source Type: research
Intracellular < em > Pseudomonas aeruginosa < /em > : An Overlooked Reservoir in the Lungs of People with Cystic Fibrosis?
Am J Respir Crit Care Med. 2024 Mar 18. doi: 10.1164/rccm.202402-0388ED. Online ahead of print.NO ABSTRACTPMID:38498854 | DOI:10.1164/rccm.202402-0388ED (Source: Am J Respir Crit Car...)
Source: Am J Respir Crit Car... - March 18, 2024 Category: Intensive Care Authors: Aur élie Crabbé Source Type: research
Intracellular < em > Pseudomonas aeruginosa < /em > : An Overlooked Reservoir in the Lungs of People with Cystic Fibrosis?
Am J Respir Crit Care Med. 2024 Mar 18. doi: 10.1164/rccm.202402-0388ED. Online ahead of print.NO ABSTRACTPMID:38498854 | DOI:10.1164/rccm.202402-0388ED (Source: Respiratory Care)
Source: Respiratory Care - March 18, 2024 Category: Respiratory Medicine Authors: Aur élie Crabbé Source Type: research
Clinical outcomes of functional endoscopic sinus surgery in cystic fibrosis patients - a single centre experience
CONCLUSIONS: There was a demonstrated clinical and symptomatic benefit of ESS in CF patients in this study. Stricter guidelines for indications for ESS need to be established with regards to CF patients who will undergo ESS in the future.PMID:38497762 | DOI:10.4193/Rhin23.057 (Source: Rhinology)
Source: Rhinology - March 18, 2024 Category: ENT & OMF Authors: Y Devabalan R Towning J Magill H Saleh C Rennie Source Type: research
Association of in-line digestive enzyme cartridge with enteral feeds on improvement in anthropometrics among pediatric patients with cystic fibrosis
CONCLUSION: Use of in-line lipase cartridge with enteral feeds improved anthropometrics, especially height, in pediatric patients with CF.PMID:38493301 | DOI:10.1002/ncp.11142 (Source: Nutrition in Clinical Practice)
Source: Nutrition in Clinical Practice - March 17, 2024 Category: Nutrition Authors: Samarth Shrivastava Karyn Shaw MinJae Lee Patricia Reitich Stacie Hunter Mary Klosterman Meghana Sathe Source Type: research
Association of in-line digestive enzyme cartridge with enteral feeds on improvement in anthropometrics among pediatric patients with cystic fibrosis
CONCLUSION: Use of in-line lipase cartridge with enteral feeds improved anthropometrics, especially height, in pediatric patients with CF.PMID:38493301 | DOI:10.1002/ncp.11142 (Source: Nutrition in Clinical Practice)
Source: Nutrition in Clinical Practice - March 17, 2024 Category: Nutrition Authors: Samarth Shrivastava Karyn Shaw MinJae Lee Patricia Reitich Stacie Hunter Mary Klosterman Meghana Sathe Source Type: research
Association of in-line digestive enzyme cartridge with enteral feeds on improvement in anthropometrics among pediatric patients with cystic fibrosis
CONCLUSION: Use of in-line lipase cartridge with enteral feeds improved anthropometrics, especially height, in pediatric patients with CF.PMID:38493301 | DOI:10.1002/ncp.11142 (Source: Nutrition in Clinical Practice)
Source: Nutrition in Clinical Practice - March 17, 2024 Category: Nutrition Authors: Samarth Shrivastava Karyn Shaw MinJae Lee Patricia Reitich Stacie Hunter Mary Klosterman Meghana Sathe Source Type: research
Correlation between trough concentration and AUC for elexacaftor, tezacaftor and ivacaftor
Cystic Fibrosis Transmembrane conductance Regulator (CFTR) modulators are the first drugs to directly target the underlying defect of the disease, and have been transforming treatment of people with Cystic Fibrosis (pwCF). The combination of elexacaftor-tezacaftor-ivacaftor (ETI) is the newest and most effective CFTR modulating medicine [1]. ETI is administered at a fixed dose in adolescents and adults (aged 12 years and older) and adjusted to age and/or weight in the pediatric population (under 12 years) [1]. (Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - March 16, 2024 Category: Respiratory Medicine Authors: Steffie E.M. Vonk, Josje Altenburg, Ron A.A. Math ôt, E. Marleen Kemper, Amsterdam Mucociliary Clearance Disease (AMCD) Research Group Source Type: research
Pharmacokinetics of polymyxin B in different populations: a systematic review
CONCLUSION: We conclude that small sample sizes, lack of multicentre collaboration, and patient homogeneity are the primary reasons for the discrepancies in the results of the current studies. In addition, most of the studies limited in the internal evaluation, which confined the implementation of model-informed precision dosing strategies.PMID:38483544 | DOI:10.1007/s00228-024-03666-w (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Xing Wang Wenqiang Xiong Maolian Zhong Yan Liu Yuqing Xiong Xiaoyi Yi Xiaosong Wang Hong Zhang Source Type: research
Challenges and mitigation strategies associated with Burkholderia cepacia complex contamination in pharmaceutical manufacturing
Arch Microbiol. 2024 Mar 14;206(4):159. doi: 10.1007/s00203-024-03921-9.ABSTRACTBurkholderia cepacia complex (BCC) is a Gram-negative, non-spore-forming bacterium with more than 20 opportunistic pathogenic species, most commonly found in soil and water. Due to their rapid mutation rates, these organisms are adaptable and possess high genomic plasticity. BCC can cause life-threatening infections in immunocompromised individuals, such as those with cystic fibrosis, chronic granulomatous disease, and neonates. BCC contamination is a significant concern in pharmaceutical manufacturing, frequently causing non-sterile product re...
Source: Archives of Microbiology - March 14, 2024 Category: Microbiology Authors: Sethuraman Prem Kumar Karupanagounder Thangaraj Uthra Vellapandian Chitra Narayanasamy Damodharan Gururaja Perumal Pazhani Source Type: research
Biofilm Formation in Mycobacterial Genus; Mechanism of Biofilm Formation and Anti-Mycobacterial Biofilm Agents
Curr Pharm Biotechnol. 2024 Mar 11. doi: 10.2174/0113892010277107240227054933. Online ahead of print.ABSTRACTMycobacterium tuberculosis, Mycobacterium leprae, and non-tuberculous mycobacteria (NTM) are among the most significant human pathogens within the Mycobacterium genus. These pathogens can infect people who come into contact with biomaterials or have chronic illnesses. A characteristic pathogenic trait of mycobacteria is the development of biofilms, which involves several molecules, such as the GroEL1 chaperone, glycopeptidolipids, and shorter-chain mycolic acids. Bacterial behavior is influenced by nutrients, ions, ...
Source: Current Pharmaceutical Biotechnology - March 14, 2024 Category: Biotechnology Authors: Sina Nasrollahian Hassan Pourmoshtagh Sahar Sabour Nahal Hadi Taher Azimi Saeed Soleiman-Meigooni Source Type: research
Pharmacokinetics of polymyxin B in different populations: a systematic review
CONCLUSION: We conclude that small sample sizes, lack of multicentre collaboration, and patient homogeneity are the primary reasons for the discrepancies in the results of the current studies. In addition, most of the studies limited in the internal evaluation, which confined the implementation of model-informed precision dosing strategies.PMID:38483544 | DOI:10.1007/s00228-024-03666-w (Source: Clinical Lung Cancer)
Source: Clinical Lung Cancer - March 14, 2024 Category: Cancer & Oncology Authors: Xing Wang Wenqiang Xiong Maolian Zhong Yan Liu Yuqing Xiong Xiaoyi Yi Xiaosong Wang Hong Zhang Source Type: research
