A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
A patient with widespread skin lesions presenting with massive pleural effusion
Tuberk Toraks. 2023 Dec;71(4):420-427. doi: 10.5578/tt.20239610.ABSTRACTMycosis fungoides is the most commonly seen type of cutaneous T-cell lymphoproliferative disease. While mycosis fungoides is linked to an increased risk of developing secondary malignancies, the occurrence of B-cell-originated disease in association with it is exceedingly rare. A 66-year-old male with persistent papillomatous skin eruption was admitted due to dyspnea. Chest X-ray, positron emission tomography, and chest computed tomography revealed axillary and mediastinal lymph node enlargement and right lower pulmonary lobe infiltration along with ri...
Source: Tuberkuloz ve Toraks - December 28, 2023 Category: Respiratory Medicine Authors: Asl ıhan Gürün Kaya Pervin Top çuoğlu Ayten Kay ı Cangır Nihal Kundak çı I şınsu Kuzu Aylin Ok çu Heper Demet Karnak Source Type: research
GSE224449 Single cell RNA sequencing of blood and skin T cells from patient with mycosis fungoides
Contributors : Yun-Tsan Chang ; Desislava Ignatova ; Emmanuella GuenovaSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCapture and processing of single skin and blood T cells was performed using the Fluidigm C1 Autoprep system. Cells were loaded at a concentration of 2,000 cells/ µL onto C1 integrated fluidic circuit chips for 5–10-µm cells. All C1 capture sites were microscopically inspected to identify the sites that contained only a single cell. Empty sites and those with multiple cells were excluded from further analysis. External RNA Controls Consortium spike-in RNA s serv...
Source: GEO: Gene Expression Omnibus - December 28, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Cancers, Vol. 16, Pages 141: Mogamulizumab Combined with Extracorporeal Photopheresis as a Novel Therapy in Erythrodermic Cutaneous T-cell Lymphoma
Conclusions: Our study presents the combination of mogamulizumab and ECP as an effective therapy in the blood and skin in CTCL with good tolerability, similar to mogamulizumab monotherapy. (Source: Cancers)
Source: Cancers - December 27, 2023 Category: Cancer & Oncology Authors: Nadia Ninosu Susanne Melchers Max Kappenstein Nina Booken Inga Hansen Ma ël Blanchard Emmanuella Guenova Chalid Assaf Sergij Goerdt Jan P. Nicolay Tags: Article Source Type: research
Role of Antigenic Stimulation in Cutaneous T-Cell Lymphomas
Cutaneous T-cell lymphoma (CTCL) involves a clonal expansion of malignant cells accumulating in the skin, a primary barrier site. CTCL has long been hypothesized to be caused or perpetuated by chronic antigen stimulation due to unknown exposures. These antigenic triggers, defined as any element that may cause activation of malignant T cells through TCR signaling, have been hypothesized to range from chemicals to microbes. This review covers current evidence supporting chemical and microbial stimuli that may act as antigenic triggers of CTCL and summarizes novel areas of investigation, in which the potential antigenicity of...
Source: Journal of Investigative Dermatology - December 26, 2023 Category: Dermatology Authors: Megan E. Gumina, Madeline J. Hooper, Xiaolong A. Zhou, Sergei B. Koralov Tags: Review Source Type: research
