Diagnostic Performance of Metagenomic Next-Generation Sequencing in Central Nervous System Cryptococcosis Using Cerebrospinal Fluid
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - September 13, 2023 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
CD146 deficiency promotes inflammatory type 2 responses in pulmonary cryptococcosis
AbstractCryptococcus neoformans (C. neoformans) is an important opportunistic fungal pathogen for pulmonary cryptococcosis. Previously, we demonstrated that CD146 mediated the adhesion ofC. neoformans to the airway epithelium. CD146 is more than an adhesion molecule. In the present study, we aimed to explore the roles of CD146 in the inflammatory response in pulmonary cryptococcosis. CD146 was decreased in lung tissues from patients with pulmonary cryptococcosis. Similarly,C. neoformans reduced pulmonary CD146 expression in mice following intratracheal inoculation. To explore the pathological roles of CD146 reduction in pu...
Source: Medical Microbiology and Immunology - August 31, 2023 Category: Microbiology Source Type: research
Molecules, Vol. 28, Pages 6224: Ethanolic Extract Propolis-Loaded Niosomes Diminish Phospholipase B1, Biofilm Formation, and Intracellular Replication of Cryptococcus neoformans in Macrophages
In conclusion, Nio-EEP mediates as an anti-virulence agent to inhibit PLB1 and biofilm production for preventing fungal colonization on lung epithelial cells and also decreases the intracellular replication of phagocytosed cryptococci. This nano-based EEP delivery might be a potential therapeutic strategy in the prophylaxis and treatment of pulmonary cryptococcosis in the future. (Source: Molecules)
Source: Molecules - August 24, 2023 Category: Chemistry Authors: Kritapat Kietrungruang Sanonthinee Sookkree Sirikwan Sangboonruang Natthawat Semakul Worrapan Poomanee Kuntida Kitidee Yingmanee Tragoolpua Khajornsak Tragoolpua Tags: Article Source Type: research
A Comprehensive Review on HIV-Associated Dermatologic Manifestations: From Epidemiology to Clinical Management
Int J Microbiol. 2023 Jul 18;2023:6203193. doi: 10.1155/2023/6203193. eCollection 2023.ABSTRACTDermatological disorders are among the most prevalent manifestations of HIV infection/acquired immunodeficiency syndrome (AIDS). In this review, we aimed to characterize the various dermatologic presentations among HIV-infected patients with a detailed categorization of the mucocutaneous signs and symptoms, their etiopathogenic factors, and clinical management. In fact, cutaneous manifestations of HIV are quite various, ranging from AIDS-specific skin eruptions (xerosis, pruritic papular eruptions, eosinophilic folliculitis, and ...
Source: Herpes - July 27, 2023 Category: Infectious Diseases Authors: Zeinab Mohseni Afshar Azadeh Goodarzi Seyed Naser Emadi Ronak Miladi Safoura Shakoei Alireza Janbakhsh Zeinab Aryanian Parvaneh Hatami Source Type: research
A Comprehensive Review on HIV-Associated Dermatologic Manifestations: From Epidemiology to Clinical Management
Int J Microbiol. 2023 Jul 18;2023:6203193. doi: 10.1155/2023/6203193. eCollection 2023.ABSTRACTDermatological disorders are among the most prevalent manifestations of HIV infection/acquired immunodeficiency syndrome (AIDS). In this review, we aimed to characterize the various dermatologic presentations among HIV-infected patients with a detailed categorization of the mucocutaneous signs and symptoms, their etiopathogenic factors, and clinical management. In fact, cutaneous manifestations of HIV are quite various, ranging from AIDS-specific skin eruptions (xerosis, pruritic papular eruptions, eosinophilic folliculitis, and ...
Source: International Journal of Microbiology - July 27, 2023 Category: Microbiology Authors: Zeinab Mohseni Afshar Azadeh Goodarzi Seyed Naser Emadi Ronak Miladi Safoura Shakoei Alireza Janbakhsh Zeinab Aryanian Parvaneh Hatami Source Type: research
