Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Developing Crowdsourced Clinical Registry Studies
This article reviews registry methodology, including the collection of data from crowdsourcing and real-world sources, that can be applied to nurse researcher and clinical research nurse skill sets. The authors illustrate a recently reported crowdsourced COVID-19 and cryptococcal disease registry that followed project management strategies and the Agency for Healthcare Research and Quality registry guidelines for planning, execution, and analysis of registries and other research methods.PMID:38511708 | DOI:10.1097/01.NAJ.0001010572.96486.87 (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - March 21, 2024 Category: Nursing Authors: Carolynn Thomas Jones Jeremy Walker Rachel L McMullen Peter G Pappas Source Type: research

Rapid duplex flap probe-based isothermal assay to identify the Cryptococcus neoformans and Cryptococcus gattii
Cryptococcosis is a life-threatening invasive fungal infection with significantly increasing mortality worldwide, which is mainly caused by Cryptococcus neoformans and Cryptococcus gattii. These two species complexes have different epidemiological and clinical characteristics, indicating the importance of accurate differential diagnosis. However, the clinically used culture method and cryptococcal capsular antigen detection couldn’t achieve the above goals. Herein, we established a novel duplex flap probe-based isothermal assay to identify the Cryptococcus neoformans and Cryptococcus gattii within 1 hour. This assay comb...
Source: Frontiers in cellular and infection microbiology - March 15, 2024 Category: Microbiology Source Type: research

3-bromopyruvate induces morphological alteration and may initiate programmed cell death in Cryptococcus neoformans cells
Arch Microbiol. 2024 Mar 12;206(4):153. doi: 10.1007/s00203-024-03894-9.ABSTRACT3-Bromopyruvate (3BP), known for its potent anticancer properties, also exhibits remarkable efficacy against the pathogenic fungus Cryptococcus neoformans. So far it has been proven that the main fungicidal activity of 3BP is based on ATP depletion and a reduction of intracellular level of glutathione. The presented study includes a broad range of methods to further investigate the mechanistic effects of 3BP on C. neoformans cells. The use of flow cytometry allowed a thorough examination of their survival during 3BP treatment, while observation...
Source: Archives of Microbiology - March 13, 2024 Category: Microbiology Authors: Katarzyna Przywara Ryszard Adamski Marta Ksi ążczyk Jakub Suchodolski Magdalena Cal Source Type: research

Sensitive bioluminescence imaging of cryptococcosis in Galleria mellonella improves antifungal screening under in vivo conditions
Volume 15, Issue 1, December 2024 . (Source: Virulence)
Source: Virulence - March 13, 2024 Category: Virology Authors: Eliane VanhoffelenLori VermoesenLauren MichielsKatrien LagrouAgustin Res éndiz-SharpeGreetje Vande Veldea Department of Imaging and Pathology, Biomedical MRI unit/MoSAIC, KU Leuven, Leuven, Belgiumb Department of Microbiology, Immunology and Transplantat Source Type: research