Guidelines Developed for Diagnosis, Management of Cryptococcosis
TUESDAY, Feb. 27, 2024 -- In a review published online Feb. 9 in The Lancet Infectious Diseases, updated guidelines are presented for the diagnosis and management of cryptococcosis.Christina C. Chang, Ph.D., from Alfred Hospital in Melbourne,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - February 27, 2024 Category: Pharmaceuticals Source Type: news

Africa: New Guidelines From WHO Recommend a Simpler, Safer Treatment for Cryptococcal Disease in People Living With HIV
[WHO] Rapid Advice (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - April 25, 2022 Category: Infectious Diseases Source Type: news

Africa: WHO Announces the Update of the Guidelines On the Diagnosis, Prevention and Management of Cryptococcal Disease in HIV-Infected Adults
[WHO] WHO has made available the membership of the Guidelines Development Group (GDG) for the update of the WHO guidelines on "The diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children; supplement to the 2016 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection." These guidelines will update existing recommendations on preferred and alternative induction therapy for management of cryptococcal disease and are s (Source: AllAfrica News: HIV-Aids and STDs)
Source: AllAfrica News: HIV-Aids and STDs - January 24, 2022 Category: Infectious Diseases Source Type: news

Sjogren's Syndrome With Nervous System Injury and Cryptococcosis Sjogren's Syndrome With Nervous System Injury and Cryptococcosis
This case details a rare form of neural involvement in Sjogren ' s syndrome, combined with pulmonary and osseous cryptococcosis due to long-term use of high-dose corticosteroids and immunosuppressants.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 12, 2021 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Severe Clinical Immunodeficiency in HIV With High CD4 Counts Severe Clinical Immunodeficiency in HIV With High CD4 Counts
While coexistence of neuromeningeal cryptococcosis and Kaposi ' s sarcoma is not unusual in HIV infection with a low CD4 count, this case demonstrates that it can occur even with a high CD4 count.Journal of Medical Case Reports (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - May 15, 2019 Category: Allergy & Immunology Tags: HIV/AIDS Journal Article Source Type: news

FDA Grants Orphan Drug Designation to Amplyx Pharmaceuticals for APX001 for Treatment of Cryptococcosis
Cryptococcal Meningitis Included in FDA Tropical Disease Priority Review Voucher Program SAN DIEGO, Feb. 11, 2019 -- (Healthcare Sales & Marketing Network) -- Amplyx Pharmaceuticals, a company developing first-in-class products for life-threatening inf... Biopharmaceuticals, FDA Amplyx Pharmaceuticals, APX001, cryptococcosis (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - February 11, 2019 Category: Pharmaceuticals Source Type: news

World AIDS Day
 takes place on the 1st December each year. It ’s an opportunity for people worldwide to unite in the fight against HIV, to show support for people living with HIV, and to commemorate those who have died from an AIDS-related illness. Founded in 1988, World AIDS Day was the first ever global health day.Cryptococcal meningitis causes an estimated 15% of all AIDS ‐related deaths globally. The disease largely affects people with advanced HIV disease, mostly in low‐ and middle‐income countries. The high death rate in part relates to limited access to diagnostic tests for the disease and the high cost and limited avail...
Source: Cochrane News and Events - November 30, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Amplyx Pharmaceuticals Receives Fourth "Qualified Infectious Disease Product" (QIDP) Designation from the FDA for APX001
QIDP Designation Granted for Treatment of Cryptococcosis Provides Priority Review, Fast-Track Status and Five Additional Years of Market Exclusivity SAN DIEGO, March 19, 2018 -- (Healthcare Sales & Marketing Network) -- Amplyx Pharmaceuticals, a compan... Biopharmaceuticals, FDA Amplyx Pharmaceuticals, Candida, Aspergillus (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - March 19, 2018 Category: Pharmaceuticals Source Type: news

MSF Response to New WHO Guidelines for HIV-Related Cryptococcal Disease
Press releaseMSF Response to New WHO Guidelines for HIV-Related Cryptococcal DiseaseMarch 07, 2018The international medical humanitarian organization Doctors Without Borders/Me ́decins Sans Frontières (MSF) welcomes the launch of updated guidance by the World Health Organization (WHO) this week on the diagnosis, treatment, and management of cryptococcal disease, an opportunistic infection mainly affecting people living with advanced stages of HIV/AIDS. (Source: MSF News)
Source: MSF News - March 7, 2018 Category: International Medicine & Public Health Authors: Brienne Prusak Source Type: news

Cryptococcosis
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - November 17, 2017 Category: General Medicine Source Type: news

The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis
Only one new class of antifungal drugs has been introduced into clinical practice in the last 30 years, and thus the identification of small molecules with novel mechanisms of action is an important goal of current anti-infective research. Here, we describe the characterization of the spectrum of in vitro activity and in vivo activity ofAR-12, a celecoxib derivative which has been tested in a phase I clinical trial as an anticancer agent. (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 10, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.
Only one new class of antifungal drugs has been introduced into clinical practice in the last 30 years, and thus the identification of small molecules with novel mechanisms of action is an important goal of current anti-infective research. Here, we describe the characterization of the spectrum of in vitro activity and in vivo activity of AR-12, a celecoxib derivative which has been tested in a phase I clinical trial as an anticancer agent. AR-12 inhibits fungal acetyl coenzyme A (acetyl-CoA) synthetase in vitro and is fungicidal at concentrations similar to those achieved in human plasma. (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 20, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Alexis Arquette Reportedly Died From AIDS. Here’s What That Really Means
Actress Alexis Arquette has died from complications related to AIDS, according to news reports, but how exactly, does someone die from the disease? Arquette, who was an activist in the transgender community, died on Sunday at age 47, according to People magazine. Members of Arquette’s family, including her sister Patricia Arquette and brother David Arquette, who are both actors, also released statements about their loss on social media. “Alexis was a brilliant artist and painter, a singer, an entertainer and an actor,” the family said in a Facebook post. “Despite the fact that there are few parts fo...
Source: Healthy Living - The Huffington Post - September 15, 2016 Category: Consumer Health News Source Type: news

Angina drug could inform a new strategy to fight cryptococcosis
A drug, more commonly used in the treatment of angina, could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis, report scientists. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 7, 2016 Category: Science Source Type: news