Non-antibiotic Prophylaxis of Infections
Praxis (Bern 1994). 2022;111(8):463-468. doi: 10.1024/1661-8157/a003822.ABSTRACTNon-antibiotic Prophylaxis of Infections Abstract. The increasing resistance to antibiotics makes the search for non-antibiotic alternatives for the treatment and prevention of - above all - respiratory and urinary tract infections crucial. Potential non-antibiotic approaches include phytopharmaceuticals (Echinacea purpurea, Pelargonium sidoides, cranberry extract), zinc, immunostimulants (OM-85 BV, OM-89), and behavior modifications. Some of these approaches are promising options; however, a high level of evidence is required before specific r...
Source: Praxis - June 8, 2022 Category: General Medicine Authors: Marco Seneghini Werner C Albrich Source Type: research

Non-antibiotic Prophylaxis of Infections
Praxis (Bern 1994). 2022;111(8):463-468. doi: 10.1024/1661-8157/a003822.ABSTRACTNon-antibiotic Prophylaxis of Infections Abstract. The increasing resistance to antibiotics makes the search for non-antibiotic alternatives for the treatment and prevention of - above all - respiratory and urinary tract infections crucial. Potential non-antibiotic approaches include phytopharmaceuticals (Echinacea purpurea, Pelargonium sidoides, cranberry extract), zinc, immunostimulants (OM-85 BV, OM-89), and behavior modifications. Some of these approaches are promising options; however, a high level of evidence is required before specific r...
Source: Praxis - June 8, 2022 Category: General Medicine Authors: Marco Seneghini Werner C Albrich Source Type: research

Non-antibiotic Prophylaxis of Infections
Praxis (Bern 1994). 2022;111(8):463-468. doi: 10.1024/1661-8157/a003822.ABSTRACTNon-antibiotic Prophylaxis of Infections Abstract. The increasing resistance to antibiotics makes the search for non-antibiotic alternatives for the treatment and prevention of - above all - respiratory and urinary tract infections crucial. Potential non-antibiotic approaches include phytopharmaceuticals (Echinacea purpurea, Pelargonium sidoides, cranberry extract), zinc, immunostimulants (OM-85 BV, OM-89), and behavior modifications. Some of these approaches are promising options; however, a high level of evidence is required before specific r...
Source: Praxis - June 8, 2022 Category: General Medicine Authors: Marco Seneghini Werner C Albrich Source Type: research

Non-antibiotic Prophylaxis of Infections
Praxis (Bern 1994). 2022;111(8):463-468. doi: 10.1024/1661-8157/a003822.ABSTRACTNon-antibiotic Prophylaxis of Infections Abstract. The increasing resistance to antibiotics makes the search for non-antibiotic alternatives for the treatment and prevention of - above all - respiratory and urinary tract infections crucial. Potential non-antibiotic approaches include phytopharmaceuticals (Echinacea purpurea, Pelargonium sidoides, cranberry extract), zinc, immunostimulants (OM-85 BV, OM-89), and behavior modifications. Some of these approaches are promising options; however, a high level of evidence is required before specific r...
Source: Praxis - June 8, 2022 Category: General Medicine Authors: Marco Seneghini Werner C Albrich Source Type: research

Viruses, Vol. 14, Pages 1101: Cranberry Pomace Extract Exerts Antiviral Activity against Zika and Dengue Virus at Safe Doses for Adult Zebrafish
In conclusion, polyphenol-rich agrifood byproducts such as berry extracts are a promising source of safe and naturally derived nutraceutical antivirals that target medically important pathogens. (Source: Viruses)
Source: Viruses - May 20, 2022 Category: Virology Authors: Laura Tamkut ė Juliano G. Haddad Nicolas Diotel Philippe Despr ès Petras Rimantas Venskutonis Chaker El Kalamouni Tags: Article Source Type: research

Molecules, Vol. 27, Pages 3190: Statistical FT-IR Spectroscopy for the Characterization of 17 Vegetable Oils
č Vegetable oils have been utilized for centuries in the food, cosmetic, and pharmaceutical industries, and they contribute beneficially to overall human health, to active skincare, and to effective treatments. Monitoring of the vegetable oils is carried out by the methods described in the European Pharmacopeia, which is time-consuming, has poor repeatability, and involves the use of toxic organic chemicals and expensive laboratory equipment. Many successful studies using IR spectroscopy have been carried out for the detection of geographical origin and adulteration as well as quantification of oxidation parameters. T...
Source: Molecules - May 17, 2022 Category: Chemistry Authors: Meta Kokalj Ladan Nina Ko čevar Glavač Tags: Article Source Type: research

The Effects of Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells: A Potential Cardioprotective and Neuroprotective Mechanism
Molecules. 2022 Apr 27;27(9):2789. doi: 10.3390/molecules27092789.ABSTRACTOxidative stress is a key underlying factor in cognitive decline and atherosclerosis. Oxidative stress occurs at the cellular level with an imbalance between reactive oxygen species and reactive nitrogen species and a deficiency in antioxidants. Mounting evidence suggests that berry flavonoids may promote cellular health by exerting antioxidant properties. Black currant and various berry extracts were tested in microglia (BV-2) and cardiomyocyte (HL-1) cell lines to study their biological effects. The principal ingredients in black currant and cranbe...
Source: Atherosclerosis - May 14, 2022 Category: Cardiology Authors: Tanisha L Currie Marguerite M Engler Cara H Olsen Victor Krauthamer Jonathan M Scott Patricia A Deuster Thomas P Flagg Source Type: research

The Effects of Blackcurrant and Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells
CONCLUSION: In summary, we demonstrated that both blackcurrant and cranberry extracts can reduce oxidative stress. Overall, blackcurrant extract was more effective in reducing oxidative stress in the HL-1 cells, whereas cranberry extract was more effective in reducing oxidative stress in the BV-2 cells. These results suggest specific cardio and neuroprotective benefits of berry flavonoids. Berry flavonoids also demonstrated promising effects as potent antioxidants. Future research should explore dose response, cell viability, and bioavailability in cellular and human models.DISCLAIMER: The opinions and assertions expressed...
Source: Atherosclerosis - May 13, 2022 Category: Cardiology Authors: Tanisha L Currie Marguerite M Engler Cara H Olsen Victor Krauthamer Jonathan M Scott Patricia A Deuster Thomas P Flagg Source Type: research

[ASAP] Rechargeable Zinc –Air Batteries with Seawater Electrolyte and Cranberry Bean Shell-Derived Carbon Electrocatalyst
Energy& FuelsDOI: 10.1021/acs.energyfuels.2c00696 (Source: Energy and Fuels)
Source: Energy and Fuels - May 5, 2022 Category: Chemistry Authors: Anggraeni Mulyadewi, Muhammad Adib Abdillah Mahbub, Yuyun Irmawati, Falihah Balqis, Celfi Gustine Adios, and Afriyanti Sumboja Source Type: research

Cranberry Supplement, D-Mannose, and Other OTC Modalities for Prevention of Recurrent UTI in Women Post-Electrofulguration
(Source: International Journal of Womens Health)
Source: International Journal of Womens Health - May 2, 2022 Category: OBGYN Tags: International Journal of Women's Health Source Type: research

Last Sail #2, View From the Belfry and Little Cranberry Island by Henry Isaacs
Recognizing the contribution art has had in the Mayo Clinic environment since the original Mayo Clinic Building was finished in 1914, Mayo Clinic Proceedings features some of the numerous works of art displayed throughout the buildings and grounds on  Mayo Clinic campuses as interpreted by the author. (Source: Mayo Clinic Proceedings)
Source: Mayo Clinic Proceedings - May 1, 2022 Category: Internal Medicine Authors: Margaret R. Wentz Tags: Art at mayo clinic Source Type: research

Molecules, Vol. 27, Pages 2789: The Effects of Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells: A Potential Cardioprotective and Neuroprotective Mechanism
omas P. Flagg Oxidative stress is a key underlying factor in cognitive decline and atherosclerosis. Oxidative stress occurs at the cellular level with an imbalance between reactive oxygen species and reactive nitrogen species and a deficiency in antioxidants. Mounting evidence suggests that berry flavonoids may promote cellular health by exerting antioxidant properties. Black currant and various berry extracts were tested in microglia (BV-2) and cardiomyocyte (HL-1) cell lines to study their biological effects. The principal ingredients in black currant and cranberry extract–delphinidin 3-rutinoside (D3R)...
Source: Molecules - April 27, 2022 Category: Chemistry Authors: Tanisha L. Currie Marguerite M. Engler Cara H. Olsen Victor Krauthamer Jonathan M. Scott Patricia A. Deuster Thomas P. Flagg Tags: Article Source Type: research

Inside Front Cover: Cranberry Proanthocyanidin and Its Microbial Metabolite 3,4 ‐Dihydroxyphenylacetic Acid, but Not 3‐(4‐Hydroxyphenyl)‐Propionic Acid, Partially Reverse Pro‐Inflammatory microRNA Responses in Human Intestinal Epithelial Cells
Mol. Nutr. Food Res. 2022,66,202100853DOI:10.1002/mnfr.202100853MicroRNAs (miRNA) are emerging as epigenetic modulators of intestinal response to nutrition. In article number2100853, Elena M. Comelli and co-workers show that cranberry-derived proanthocyanidin (PAC) and its microbial metabolites affect the expression of intestinal miRNAs and are able to partially reverse an inflammatory insult to maintain intestinal homeostasis. (Source: Molecular Nutrition and Food Research)
Source: Molecular Nutrition and Food Research - April 20, 2022 Category: Food Science Authors: Zoe Lofft, Amel Taibi, Paraskevi Massara, Tomas Tokar, Inke Paetau ‐Robinson, Christina Khoo, Elena M. Comelli Tags: Inside Front Cover Source Type: research

Non-antibiotic Approaches to Preventing Pediatric UTIs: a Role for D-Mannose, Cranberry, and Probiotics?
AbstractPurpose of ReviewWhile antibiotics have been a staple in the management and even prevention of urinary tract infections (UTIs), it is not without significant consequences due to intolerance and development of antibiotic resistant bacteria. These concerns necessitate alternatives to antibiotic use in the management of pediatric UTIs. This review seeks to evaluate non-antibiotic means of preventing UTI in the pediatric population.Recent FindingsThe search for preventative alternatives to antibiotics has included D-mannose, cranberry, and probiotics. These products similarly work through competitive inhibition of urop...
Source: Current Urology Reports - April 20, 2022 Category: Urology & Nephrology Source Type: research

Non-antibiotic treatment of acute urinary tract infection in primary care: a qualitative study
CONCLUSION: Many women with auUTIs are open to trying non-antibiotic treatments first in certain situations. There is scope for more dialogue between primary care clinicians and patients with auUTI around delaying antibiotic treatment and using non-antibiotic options initially, which could reduce antibiotic consumption for this common infection.PMID:35314431 | DOI:10.3399/BJGP.2021.0603 (Source: The British Journal of General Practice)
Source: The British Journal of General Practice - March 22, 2022 Category: Primary Care Authors: Oghenekome A Gbinigie Sarah Tonkin-Crine Christoper C Butler Carl J Heneghan Anne-Marie Boylan Source Type: research