The Effects of Blackcurrant and Berry Extracts on Oxidative Stress in Cultured Cardiomyocytes and Microglial Cells

CONCLUSION: In summary, we demonstrated that both blackcurrant and cranberry extracts can reduce oxidative stress. Overall, blackcurrant extract was more effective in reducing oxidative stress in the HL-1 cells, whereas cranberry extract was more effective in reducing oxidative stress in the BV-2 cells. These results suggest specific cardio and neuroprotective benefits of berry flavonoids. Berry flavonoids also demonstrated promising effects as potent antioxidants. Future research should explore dose response, cell viability, and bioavailability in cellular and human models.DISCLAIMER: The opinions and assertions expressed herein are those of the author(s) and do not necessarily reflect the official policy or position of the Uniformed Services University or the Department of Defense.CONFLICT OF INTEREST: Neither I nor my family members have a financial interest in any commercial product, service, or organization providing financial support for this research.PMID:35552822 | DOI:10.1096/fasebj.2022.36.S1.R2805
Source: Atherosclerosis - Category: Cardiology Authors: Source Type: research