Fight Aging! Newsletter, August 2nd 2021
This study aimed to determine the association between: (i) cognitive decline and bone loss; and (ii) clinically significant cognitive decline on Mini Mental State Examination (MMSE) over the first 5 years and subsequent fracture risk over the following 10 years. A total of 1741 women and 620 men aged ≥65 years from the population-based Canadian Multicentre Osteoporosis Study were followed from 1997 to 2013. Over 95% of participants had normal cognition at baseline. After multivariable adjustment, cognitive decline was associated with bone loss in women but not men. Approximately 13% of participants experienced sign...
Source: Fight Aging! - August 1, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
BAFT Upregulation Makes T Cells Resistant to Exhaustion
When faced with long-lasting challenges, such as cancer or persistent infections that the immune system struggles to clear, T cells of the adaptive immune system can become exhausted. The exhausted cells lose function, diminishing both the immediate immune response and the ability to form immune memory that will enable a robust future response to the same threat. Researchers see this in the engineered T cells used in chimeric antigen receptor (CAR) T cell therapies, and there is thus a strong incentive to find ways to address the issue by identifying important causes or regulators of T cell exhaustion, and interfering to p...
Source: Fight Aging! - July 28, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Peptide Coated Nanoparticles as a Basis for a Non-Invasive Test for Cancer
A reliable, low-cost means of early detection of cancer would be of great benefit. Approaches to the treatment are advancing to the point at which very early stage cancer has a high rate of survival, and the side-effects of treatments for early stage cancer are becoming less onerous. In the ideal world, a yearly physical would include a low-cost cancer screen that robustly detects even small volumes of cancerous tissue. Various approaches are under development, such as those based on identification of signal molecules in the bloodstream. The alternative approach noted here, based on the use of engineered nanoparticles, is ...
Source: Fight Aging! - July 27, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Google ’ s Masterplan for Healthcare
With 7% of Google searches – or 70,000 per minute – being health-related, it was only a matter of time before the search giant aimed to be a healthcare giant. Google hasn’t been particularly shy at expressing these ambitions either. It purchased Fitbit for $2.1 billion and had a dedicated healthcare offshoot from its A.I. branch, Deepmind.
In this new article series exploring the latest moves by tech giants into healthcare, we will look at recent developments coming from Google. Previous entries looked at the moves of Google’s competitors Amazon and Apple, and provided insights into the trends that those companies ...
Source: The Medical Futurist - July 27, 2021 Category: Information Technology Authors: berci.mesko Tags: Artificial Intelligence in Medicine Digital Health Research Future of Medicine Future of Pharma Genomics Health Sensors & Trackers Portable Medical Diagnostics Security & Privacy AI genetics google Healthcare Innovation technolog Source Type: blogs
Today is the day you ’ll have to die
She was listless in bed with agonal breathing — only 63 years old. Before stage 4 colon cancer claimed my mother, she chose to come home to her house … her bedroom, where she’d stare out her window at the dogwood trees that symbolized the blood of Jesus. A once-vibrant Italian Catholic and mother ofRead more …Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 13, 2021 Category: General Medicine Authors: < span itemprop="author" > < a href="https://www.kevinmd.com/blog/post-author/debbie-moore-black" rel="tag" > Debbie Moore-Black, RN < /a > < /span > Tags: Conditions Palliative Care Source Type: blogs
GI Genius Polyp Detection System: Interview with Giovanni Di Napoli, President, Gastrointestinal at Medtronic
We recently reported on the de novo FDA clearance received by Medtronic for its GI Genius AI polyp detection system. The product is hugely flexible as it works with any video colonoscope and provides AI powered assistance for clinicians in identifying colorectal polyps during colonoscopies.
Medtronic reports that the system has significantly improved polyp detection rates, which should translate to better colorectal cancer patient outcomes through prompt diagnosis and early treatment.
As a clinician performs a colonoscopy the system analyzes the video data and highlights suspected polyps using a green box on the vid...
Source: Medgadget - May 13, 2021 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive GI Source Type: blogs
Foreword to Wheat Belly Revised & Expanded Edition
An excerpt from the Wheat Belly Revised & Expanded Edition:
Have you ever come home from the grocery store with a fresh container of milk, opened it and immediately realized that it was bad—sour-smelling, curdled, unfit to drink?
Feed it to the cat? Probably not. Lighten your coffee? I don’t think so. Pour it down the sink—yeah, that’s the ticket. Or maybe go back to the store with some of the curdled remains and ask for your money back.
That is what your reaction to conventional dietary advice should be. You should wrinkle your nose at the bad smell that emanates from advice that creates an astonish...
Source: Wheat Belly Blog - May 7, 2021 Category: Cardiology Authors: Dr. Davis Tags: Open grain-free wheat belly Source Type: blogs
Is IBD an underrecognized health problem in minority groups?
As many people know, inflammatory bowel disease (IBD) is a complex condition affecting the intestine, which is the part of the digestive tract that helps digest food and remove water, salt, and waste.
But you might not know this: in recent years in the US, IBD is being diagnosed more often among people who are Black, Hispanic/Latinx, East and Southeast Asian, or from other minority groups than it was in past decades.
Is this a true rise in cases? Is IBD underrecognized in minority populations? While we don’t have all the answers yet, exploring health disparities in IBD and explaining its symptoms may encourage more peopl...
Source: Harvard Health Blog - May 7, 2021 Category: Consumer Health News Authors: Adjoa Anyane-Yeboa, MD, MPH Tags: Digestive Disorders Health Health care disparities Inflammation Source Type: blogs
The Benefits of Taking a Break from Alcohol
Alcohol abuse and alcoholism are serious issues across the nation. In fact, there are over 95,000 alcohol-related deaths each and every year. Despite how problematic alcohol can be, it is still the most used substance across the country – many don’t realize the risks and health-related problems associated with alcohol.
Before we look at how taking even a short break can help you in the long-term let’s first look at the major risks associated with excessive alcohol use and binge drinking.
Major Risks of Alcohol Use
When it comes to alcohol abuse, there are many issues that can occur – from long-term physica...
Source: PickTheBrain | Motivation and Self Improvement - May 5, 2021 Category: Consumer Health News Authors: Joe Gilmore Tags: depression featured happiness health and fitness productivity tips self-improvement addiction alcohol self improvement Source Type: blogs
Pumping Iron: The Heavy Lifting Iron Does in Our Bodies
Our blood appears red for the same reason the planet Mars does: iron. The element may bring to mind cast-iron pans, wrought-iron fences, or ancient iron tools, but it’s also essential to life on Earth. All living organisms, from humans to bacteria, need iron. It’s crucial for many processes in the human body, including oxygen transport, muscle function, proper growth, cell health, and the production of several hormones.
Iron is the reason both our blood and the planet Mars appear red. The element also makes up the majority of Earth’s core and generates the planet’s magnetic field. Credit: Compound Interest....
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - May 5, 2021 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Cellular Processes Proteins Source Type: blogs
3D Printed Shields Protect Guts During Radiotherapy
Researchers at Brigham and Women’s Hospital and MIT have developed 3D printed shields to protect the gastrointestinal tract from the side effects of radiotherapy. Using CT scans, the devices can be custom printed to suit each patient’s anatomy. The materials they’re made of contain high atomic number elements that help to shield tissues from gamma and X-rays.
Radiotherapy can be highly effective at targeting tumors and helping to shrink them. However, it can also have significant consequences for nearby healthy tissues. The side effects can be particularly pronounced in the delicate tissues of the mouth and g...
Source: Medgadget - April 27, 2021 Category: Medical Devices Authors: Conn Hastings Tags: GI Materials Radiation Oncology Radiology Source Type: blogs
Fight Aging! Newsletter, April 26th 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - April 25, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Calorie Restriction as an Adjuvant Cancer Treatment
Calorie restriction and intermittent fasting have been extensively studied in the context of aging, and most of the age-slowing interventions so far tested in animal studies are derived in some way from a knowledge of the stress response mechanisms triggered by a lowered calorie intake. The long term effects of calorie restriction and fasting in short-lived species are quite different from those in long-lived species: only the short-lived species exhibit a meaningful extension of life span, as much as 40% in mice. Yet the short-term effects on metabolism and cellular mechanisms are very similar. The beneficial response to ...
Source: Fight Aging! - April 19, 2021 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
FDA Clears First AI Polyp Detection System for Colonoscopies
Medtronic won FDA de novo clearance for its GI Genius endoscopy technology that can spot suspicious lesions during routine colonoscopy exams. The system works with any video colonoscope and can even process pre-recorded colonoscopies.
Even highly experienced gastroenterologists can miss a polyp while navigating through the colon. Computer vision technology can carefully process the entirety of every video frame to spot any irregularities associated with polyps. According to Medtronic, “the GI Genius module has demonstrated a 14% absolute increase in ADR [adenoma detection rate] compared to colonoscopy alone fo...
Source: Medgadget - April 15, 2021 Category: Medical Devices Authors: Medgadget Editors Tags: GI Source Type: blogs
Fight Aging! Newsletter, March 29th 2021
Discussion of Systemic Inflammation and its Contribution to Dementia
Fisetin Reduces D-Galactose Induced Cognitive Loss in Mice
Reprogramming Cancer Cells into Normal Somatic Cells
Considering Longevity Medicine and the Education of Physicians
Researchers Generate Thyroid Organoids Capable of Restoring Function in Mice
In Search of Transcriptional Signatures of Aging
A Pace of Aging Biomarker Correlates with Manifestations of Aging
Targeting Tissues with Extracellular Vesicles
Calorie Restriction Slows Aging of the Gut Microbiome in Mice
Mitochondrial DNA Heteroplasmy in the Aging Heart
Evidence...
Source: Fight Aging! - March 28, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
