Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Real-World Evidence on Clinical Outcomes of Commonly Used Antidepressants in Older Adults Initiating Antidepressants for Depression: A Nationwide Cohort Study in Denmark
CONCLUSIONS: This real-world evidence suggests that clinical outcomes may vary among initiators of commonly used antidepressants in older adults, which may inform benefit-risk evaluation at treatment initiation, and highlights the importance of careful selection of antidepressant treatment.PMID:37849303 | DOI:10.1176/appi.ajp.20230356 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 18, 2023 Category: Psychiatry Authors: Kazi Ishtiak-Ahmed Katherine L Musliner Kaj Sparle Christensen Erik Lykke Mortensen Andrew A Nierenberg Christiane Gasse Source Type: research
Antidepressant-like effects of the Punica granatum and citalopram combination are associated with structural changes in dendritic spines of granule cells in the dentate gyrus of rats
Introduction: Natural products such as phytoestrogens-enriched foods or supplements have been considered as an alternative therapy to reduce depressive symptoms associated with menopause. It is known that the aqueous extract of Punica granatum (AE-PG) exerts antidepressant-like effects by activating β-estrogen receptors and facilitates the antidepressant response of the clinical drug citalopram (CIT). However, the effects on neuroplasticity are unknown. Objectvie investigated the antidepressant-like response of combining AE-PG and CIT at sub-optimal doses, analyzing their effects on the formation and maturation of dendrit...
Source: Frontiers in Pharmacology - October 13, 2023 Category: Drugs & Pharmacology Source Type: research
