DM / DNB Cardiology Entrance Mock Test 10
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Congratulations - you have completed DM / DNB Cardiology Entrance Mock Test 10.
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Source: Cardiophile MD - February 1, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
Avoid Dialysis by Stem Cell Transplant in CKD Patients
Could dialysis be avoided? This is the doubt from many patients with Chronic
Kidney Disease(CKD). Luckily, stem cell technology may help you realize your dream.As we all know, if CKD is not well controlled, it may develop into the End Stage Renal Disease(ESRD), or sometimes we usually call it as Uremia. At this stage, ... (Source: All Kidney News)
Source: All Kidney News - January 23, 2016 Category: Urology & Nephrology Authors: jadhavbca Tags: Kidney News Source Type: blogs
Test results 2016
About 15 months have zoomed by since my last lab tests and so I was delighted to find no significant change in today's test results. My blood creatinine level remains at 2.0mg/dl, which is right where it was when I was first diagnosed with chronic kidney disease almost seven years ago. Kidney disease tends to progress so I consider avoiding progression an achievement!
You can view 7 years of my test results, from initial diagnosis to present, here.
I can't say if my attempt to live a healthy lifestyle has been a factor in avoiding progression of the disease but it probably doesn't hurt (and has other benefits...
Source: All Kidney News - January 17, 2016 Category: Urology & Nephrology Authors: admin Tags: Uncategorized Source Type: blogs
Towards an Implanted Artificial Kidney
Filtration in biology is a tractable problem to solve, to build devices that can carry out at least part of the function of organs like the kidneys by removing unwanted substances from the blood. There are already numerous fairly effective means of carrying out dialysis outside the body, for example. These technologies will improve and minimize in the years ahead until the state of the art is a durable, implanted artificial organ intended to augment or largely replace the kidneys. One group of researchers here provide an update on their current progress towards this goal:
A surgically implantable, artificial kidney based ...
Source: Fight Aging! - November 11, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Test your medicine knowledge: 59-year-old man with gout
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 59-year-old man is evaluated for a 6-month history of gout. He was doing well on colchicine and allopurinol but developed hypersensitivity to allopurinol, which resolved with cessation of the agent. He then began to have more frequent gout flares; two flares occurred in the past month and were treated with prednisone. History is also significant for hypertension, chronic kidney disease, and dyslipidemia. Current medications are colchicine, lisinopril, metoprolol, and simvastatin.
On physical examination, tempe...
Source: Kevin, M.D. - Medical Weblog - November 7, 2015 Category: Journals (General) Authors: mksap Tags: Conditions Rheumatology Source Type: blogs
Using EHR Data to Manage Hypertension More Aggressively
By JOSH GRAY
The NIH (National Institutes of Health) recently released initial results from its SPRINT (Systolic Blood Pressure Intervention Trial) study, suggesting more aggressive treatment for hypertension may reduce risk for cardiovascular events by 30 percent and the risk of death by 25 percent.
The SPRINT group recruited over 9,000 non-diabetic subjects aged 50 or older with systolic blood pressure (SBP) over 130. Individuals were then randomly assigned to either a standard treatment goal of lowering SBP below 140 or a more intensive treatment goal of lowering SBP below 120. The findings were sufficiently compellin...
Source: The Health Care Blog - October 6, 2015 Category: Consumer Health News Authors: Simon Nath Tags: Uncategorized Source Type: blogs
Diuretic or Calcium Channel Blocker for CKD
It has been suggested by researchers that the diuretic clorthalidone should be the first line of antihypertensive therapy with a few caveats. Firstly in the presence of certain co-morbidities other drugs with a proven track record of reducing end organ damage should be instituted as first line instead. Thus it has been suggested that in patients with diabetic kidney disease and angiotensin receptor blocker (ARB) be commenced early due to its proven reno-protective effects in type 2 diabetics with kidney disease.
The results of the ACCOMPLISH trial as reported in the LANCET may change the above approach. From the available ...
Source: All Kidney News - September 29, 2015 Category: Urology & Nephrology Authors: jadhavbca Tags: Kidney News ACCOMPLISH Calcium Channel Blocker CKD DIOVAN Source Type: blogs
Considering Klotho Delivery as a Means to Reduce Age-Related Stem Cell Decline
Today I'll point out an open access paper on the longevity-related gene klotho. Some researchers see therapies to adjust levels of the klotho protein produced from this genetic blueprint as a possible way to slow some of the effects of aging, particularly those connected to regeneration and stem cell activity. Work on this is slow-moving and painstaking, as for any similar approaches.
Yet a fairly large section of the medical research community is now devoted to at least partial and temporary restoration of tissue maintenance by stem cells in the old. A good fraction of the frailty and failure of aging results not just fr...
Source: Fight Aging! - September 14, 2015 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Induced Pluripotent Stem Cells as Kidney Disease Therapy
Researchers here investigate the transplant of induced pluripotent stem cells-derived progenitor cells produced from the recipient's tissues as a possible way to spur regeneration of kidney damage, such as the fibrosis characteristic of chronic kidney disease. Like many forms of stem cell therapy, this appears to produce benefits due to the signal molecules generated by the transplanted cells. That in turn suggests that near future therapies emerging from stem cell research will largely involve providing the signals directly, not via cells, in ever more sophisticated efforts to control the behavior of native cells. This pr...
Source: Fight Aging! - July 22, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
The Vascular Secret of Klotho
The klotho enzyme can be manipulated to slow aging in laboratory animals, and more circulating klotho is associated with enhanced cognitive function. Like many of the mechanisms found to modestly slow aging in short-lived species in the laboratory, the activities of klotho touch on many systems in the body and are far from completely cataloged. This is an example of some of the more speculative areas of investigation:
Klotho-deficient mice manifest a phenotype resembling accelerated human ageing. Klotho-deficient mice have a short lifespan, and overexpression of Klotho in mice extends lifespan significantly in comparison ...
Source: Fight Aging! - June 1, 2015 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Considering Angiotensin II and Aging
When reading about research into any particular gene or protein and its influence on aging it is important to keep in mind that our biochemistry is a network of connections. Nothing happens in isolation, and any change in the amount of a particular protein or interference in its activities will cause a cascade of consequences though its interactions with other proteins. Thus there are probably comparatively few important mechanisms involved in determining natural variations in longevity but many distinct ways to manipulate those mechanisms.
Decades of research focused on treating cardiovascular disease and hypertension ha...
Source: Fight Aging! - May 4, 2015 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Embedding Civil Legal Aid Services In Care for High-Utilizing Patients Using Medical-Legal Partnership
Mr. Jackson (not his real name) is a 42-year old man who was hospitalized three times in a seven-month period at Lancaster General Hospital in Pennsylvania. These hospitalizations were due to complications from chronic obstructive pulmonary disease, morbid obesity, depression, chronic kidney disease, and lower extremity non-healing ulcers. He was depressed and concerned that he was not able to move beyond the revolving door of frequent inpatient admissions.
Mr. Jackson was also incurring a large debt due to copays and uncovered services and medications. But his problems were not just medical. He was having legal problems ...
Source: Health Affairs Blog - April 22, 2015 Category: Health Management Authors: Jeffrey Martin Tags: Featured Innovations in Care Delivery civil legal aid Health Law super-utilizers Source Type: blogs
A national study of practice patterns in UK renal units in the use of dialysis and conservative kidney management to treat people aged 75 years and over with chronic kidney failure
National Institute for Health Research - Conservative kidney management (CKM) is recognised as an alternative to dialysis for a significant number of older adults with multimorbid stage 5 chronic kidney disease (CKD5). However, little is known about the way CKM is delivered or how it is perceived. The aim of this study is to determine the practice patterns for the CKM of older patients with CKD5, to inform service development and future research.
Report
Summary
Abstract (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - April 10, 2015 Category: UK Health Authors: The King's Fund Information & Knowledge Service Source Type: blogs
Well, Stayin' Alive
In Democracy (which you should bookmark) Diane E. Meier has a review of Atul Gawande's "The Way We Die Now." The irony, if that's the right word, is that the central issue is how long we live.In 1900, life expectancy at birth in the U.S. was 47.3 years. Alzheimer's, cancer, heart disease, osteoarthritis and osteoporosis, chronic kidney disease, frailty and infirmity -- very few people had to worry about all of that. And if you did get cancer or heart disease or dementia or kidney disease? At least the good news is that you didn't have to live with them for very long.So our problem is that we have created a new stage of lif...
Source: Stayin' Alive - April 2, 2015 Category: American Health Source Type: blogs
The insufferable patient: You know the one
He is that new patient to the clinic.
You know the one.
He is the “multiple chronic conditions” patient. Diabetes, hypertension, COPD, chronic kidney disease, congestive heart failure, arthritis — it would probably be quicker to name the conditions he doesn’t have. You let out a deep sigh before entering the room.
Continue reading ...
Your patients are rating you online: How to respond. Manage your online reputation: A social media guide. Find out how. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 14, 2015 Category: Journals (General) Authors: Jennifer Chevinsky Tags: Education Medical school Source Type: blogs
