The role of Ca < sup > 2+ < /sup > signalling and InsP3R in the pathogenesis of intrahepatic cholestasis of pregnancy
CONCLUSIONS: Our results revealed that the expression of InsP3R and serum Ca2+ levels was significantly decreased in the liver tissue of ICP model rats. Additionally, Ca2+ levels were found to be negatively correlated with the level of glycocholic acid.PMID:38685831 | DOI:10.1080/01443615.2024.2345276 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - April 30, 2024 Category: OBGYN Authors: Dan Pan Mengting Jiang Guoxian Tao Jinmei Shi Zhiwei Song Ren Chen Dongguo Wang Source Type: research

Clinical characteristics and outcomes of acute liver failure in neonates: a retrospective cohort in China
Conclusion: Hypoxic/ischemic injury and infection are the predominant etiologies of NALF in China. The overall prognosis of NALF is poor, but its short-term prognosis is determined by the etiology. What is Known: • Neonatal acute liver failure (NALF) is a rare disorder with limited cohort studies, especially in China. • Gestational alloimmune liver disease, viral infections (especially herpes simplex virus), metabolic diseases and ischemic insults are common etiologies of NALF, which are significantly different from other populations. • There are no reliable biochemical markers to predict the outcome of NALF. What is...
Source: Herpes - April 30, 2024 Category: Infectious Diseases Authors: Suhua Xu Peng Zhang Mengmeng Ge Yuanyuan Shan Guoqiang Cheng Source Type: research

Research development and trend of intrahepatic cholestasis of pregnancy: A bibliometric analysis
Asian J Surg. 2024 Apr 29:S1015-9584(24)00740-1. doi: 10.1016/j.asjsur.2024.04.080. Online ahead of print.NO ABSTRACTPMID:38688759 | DOI:10.1016/j.asjsur.2024.04.080 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 30, 2024 Category: Surgery Authors: Yan-Nan Zhou Hong-Ying Luo Jing Lin Source Type: research

The role of Ca < sup > 2+ < /sup > signalling and InsP3R in the pathogenesis of intrahepatic cholestasis of pregnancy
CONCLUSIONS: Our results revealed that the expression of InsP3R and serum Ca2+ levels was significantly decreased in the liver tissue of ICP model rats. Additionally, Ca2+ levels were found to be negatively correlated with the level of glycocholic acid.PMID:38685831 | DOI:10.1080/01443615.2024.2345276 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - April 30, 2024 Category: OBGYN Authors: Dan Pan Mengting Jiang Guoxian Tao Jinmei Shi Zhiwei Song Ren Chen Dongguo Wang Source Type: research

Clinical characteristics and outcomes of acute liver failure in neonates: a retrospective cohort in China
Conclusion: Hypoxic/ischemic injury and infection are the predominant etiologies of NALF in China. The overall prognosis of NALF is poor, but its short-term prognosis is determined by the etiology. What is Known: • Neonatal acute liver failure (NALF) is a rare disorder with limited cohort studies, especially in China. • Gestational alloimmune liver disease, viral infections (especially herpes simplex virus), metabolic diseases and ischemic insults are common etiologies of NALF, which are significantly different from other populations. • There are no reliable biochemical markers to predict the outcome of NALF. What is...
Source: Herpes - April 30, 2024 Category: Infectious Diseases Authors: Suhua Xu Peng Zhang Mengmeng Ge Yuanyuan Shan Guoqiang Cheng Source Type: research

Research development and trend of intrahepatic cholestasis of pregnancy: A bibliometric analysis
Asian J Surg. 2024 Apr 29:S1015-9584(24)00740-1. doi: 10.1016/j.asjsur.2024.04.080. Online ahead of print.NO ABSTRACTPMID:38688759 | DOI:10.1016/j.asjsur.2024.04.080 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 30, 2024 Category: Surgery Authors: Yan-Nan Zhou Hong-Ying Luo Jing Lin Source Type: research

The role of Ca < sup > 2+ < /sup > signalling and InsP3R in the pathogenesis of intrahepatic cholestasis of pregnancy
CONCLUSIONS: Our results revealed that the expression of InsP3R and serum Ca2+ levels was significantly decreased in the liver tissue of ICP model rats. Additionally, Ca2+ levels were found to be negatively correlated with the level of glycocholic acid.PMID:38685831 | DOI:10.1080/01443615.2024.2345276 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - April 30, 2024 Category: OBGYN Authors: Dan Pan Mengting Jiang Guoxian Tao Jinmei Shi Zhiwei Song Ren Chen Dongguo Wang Source Type: research

Research development and trend of intrahepatic cholestasis of pregnancy: A bibliometric analysis
Asian J Surg. 2024 Apr 29:S1015-9584(24)00740-1. doi: 10.1016/j.asjsur.2024.04.080. Online ahead of print.NO ABSTRACTPMID:38688759 | DOI:10.1016/j.asjsur.2024.04.080 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 30, 2024 Category: Surgery Authors: Yan-Nan Zhou Hong-Ying Luo Jing Lin Source Type: research

The role of Ca < sup > 2+ < /sup > signalling and InsP3R in the pathogenesis of intrahepatic cholestasis of pregnancy
CONCLUSIONS: Our results revealed that the expression of InsP3R and serum Ca2+ levels was significantly decreased in the liver tissue of ICP model rats. Additionally, Ca2+ levels were found to be negatively correlated with the level of glycocholic acid.PMID:38685831 | DOI:10.1080/01443615.2024.2345276 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - April 30, 2024 Category: OBGYN Authors: Dan Pan Mengting Jiang Guoxian Tao Jinmei Shi Zhiwei Song Ren Chen Dongguo Wang Source Type: research

Research development and trend of intrahepatic cholestasis of pregnancy: A bibliometric analysis
Asian J Surg. 2024 Apr 29:S1015-9584(24)00740-1. doi: 10.1016/j.asjsur.2024.04.080. Online ahead of print.NO ABSTRACTPMID:38688759 | DOI:10.1016/j.asjsur.2024.04.080 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - April 30, 2024 Category: Surgery Authors: Yan-Nan Zhou Hong-Ying Luo Jing Lin Source Type: research

The role of Ca < sup > 2+ < /sup > signalling and InsP3R in the pathogenesis of intrahepatic cholestasis of pregnancy
CONCLUSIONS: Our results revealed that the expression of InsP3R and serum Ca2+ levels was significantly decreased in the liver tissue of ICP model rats. Additionally, Ca2+ levels were found to be negatively correlated with the level of glycocholic acid.PMID:38685831 | DOI:10.1080/01443615.2024.2345276 (Source: Journal of Obstetrics and Gynaecology)
Source: Journal of Obstetrics and Gynaecology - April 30, 2024 Category: OBGYN Authors: Dan Pan Mengting Jiang Guoxian Tao Jinmei Shi Zhiwei Song Ren Chen Dongguo Wang Source Type: research

Dengue-related acute liver failure —A scoping review
AbstractInfection by dengue virus is common in tropical countries. Hepatic involvement in dengue can range from asymptomatic elevation of transaminases to life-threatening acute liver failure (ALF). Dengue-related ALF (DALF) is responsible for significant morbidity and mortality, especially in Southeast Asia. However, there is a scarcity of literature on DALF, necessitating a thorough examination of its clinical determinants and management strategies. All relevant studies related to DALF were reviewed until December 2023. Case reports, case series and studies reporting ALF in dengue infection were included. Demographics, c...
Source: Indian Journal of Gastroenterology - April 30, 2024 Category: Gastroenterology Source Type: research