Determining the propulsion mechanism of a water strider
A water strider swims across water sprinkled with thymol blue.
More about this Image
In this image, a layer of water was sprinkled with the chemical thymol blue, which established the Marangoni convection responsible for the evident fine-scale texture pictured here, as part of ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - December 8, 2020 Category: Science Source Type: video
Dipolar vortices generated in wake of an adult water strider
Dipolar vortices generated in the wake of an adult water strider.
More about this Image
In this image, when the chemical thymol blue is sprinkled on the water surface, Marangoni convection in the suspended fluid produces a swirling texture. Motions of the surface of a liquid ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - December 8, 2020 Category: Science Source Type: video
Black Spot, Black Death, Black Pearl: the Tales of Bacterial Effectors
WALS
Bacteria will do whatever it takes to outwit their hosts. Kim Orth's lab studies their crafty ways, figuring out exactly how pathogens manipulate host cells for their own benefit and survival. Her team's work has uncovered unexpected strategies that bacteria use to survive and spread. Her research group has also helped discern normal signaling processes in host cells, including mechanisms that can be exploited to treat disease. They have found that Yersinia, the bacteria that causes plague, silences cells' attempts to summon immune cells by chemically modifying a key signaling protein so that it can no longer be switc...
Source: Videocast - All Events - November 25, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
SMART Biosensors: A New Modality to Objectively Quantify Pain
WALS
Our research is focused on the basic and applied aspects of bioanalytical, materials and environmental chemistry. We are interested in the design and development of chemical and biological sensors that are inspired by the recognition processes found in nature. Perhaps the best and most sophisticated recognition process is found in the human body. For example, our senses of smell, tastes and ability to respond to temperature variation all occur via living polymer interfaces. Even cellular processes are regulated by cell walls, comprising dynamic macromolecules that are capable of sensing and responding to specific chem...
Source: Videocast - All Events - November 25, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
3D rendering of genetically targeted chemical assembly of functional materials
The golden color in this 3D rendering depicts biocompatible materials attached to neurons, materials deposited using a process called genetically targeted chemical assembly (GTCA). In GTCA, researchers use genetic information to target cells and precisely deposit polymers, sparing the neighboring ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - October 1, 2020 Category: Science Source Type: video
From Mechanisms to Medicines: Realizing the DREAM of an Alzheimer's Cure
NIH Director's Seminar Series
The repeated failures of disease-modifying treatments for Alzheimer ’ s disease (AD) have increased the urgency to identify novel therapeutic targets and biomarkers for AD and related dementias (ADRD). Dr. Thambisetty's Clinical and Translational Neuroscience Section has applied a systems biology approach leveraging deep molecular phenotyping by multi-OMICs methods in brain and blood in combination with multi-modal neuroimaging and epidemiological analyses to identify abnormal metabolic pathways in ADRD associated with severity of pathology and expression of clinical symptoms. These studies ...
Source: Videocast - All Events - September 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH Director's Seminar Series
The repeated failures of disease-modifying treatments for Alzheimer ’ s disease (AD) have increased the urgency to identify novel therapeutic targets and biomarkers for AD and related dementias (ADRD). Dr. Thambisetty's Clinical and Translational Neuroscience Section has applied a systems biology approach leveraging deep molecular phenotyping by multi-OMICs methods in brain and blood in combination with multi-modal neuroimaging and epidemiological analyses to identify abnormal metabolic pathways in ADRD associated with severity of pathology and expression of clinical symptoms. These studies have added to a growing body o...
Source: Videocast - All Events - September 2, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
New Tools to Explore the Biology of Bacterial Polysaccharides
NIH Common Fund Glycoscience Program (CF-GSP) workshop " New Tools to Explore the Biology of Bacterial Polysaccharides "
This workshop is being Co-chaired by Dr. Catherine Leimkuhler Grimes, Chair, CF-GSP Tools Group& Professor, Department of Chemistry& Biochemistry, University of Delaware& Dr. Danielle Dube, ACS CARB Division Secretary& Professor of Chemistry& Biochemistry, Bowdoin College. Presentations will highlight the latest findings of NIH supported researchers who are developing new methods and tools for the study of microbes and applying these tools to understand bacterial metabolism, interaction(s) with the immun...
Source: Videocast - All Events - July 30, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
New Tools for Finding Glycans in the PDB & Using the Information to Model 3D Structures of Glycans and GlycoProteins
Glycans play a critical role in nearly all aspects of biology, ranging from how our bodies recognize and fight viruses and bacteria to how proteins are moved throughout our cells to perform different tasks. The Common Fund ’ s Glycoscience program (CF-GSP) is creating new resources, tools, and methods to make the study of glycans (sugars) more accessible to the broader research community. The Protein Data Bank (PDB) contains more than 160,000 3D structures of biological macromolecules 20% of which contain carbohydrates as ligands or as chemical modifications. Unfortunately, much of the PDB's carbohydrate structural data ...
Source: Videocast - All Events - July 28, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH COVID-19 Lecture: SARS-CoV-2 T Cell Responses in Exposed and Non-Exposed Subjects
NIH COVID-19 Lecture Series
Dr. Sette will review data examining the nature and specificity of T cell responses to SARS-CoV-2 from convalescent and acute donors, and in non-exposed subjects. Over the past three decades, the Sette lab has defined in chemical terms the specific structures that the immune system recognizes, and it has capitalized on this knowledge to measure and understand immune responses. This approach uses epitopes as specific probes to define the immune signatures associated with productive/protective immunity versus deficient immunity/immunopathology. Turning to SARS-CoV-2, Dr. Sette and his colleagues a...
Source: Videocast - All Events - July 27, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
Electron microscope images showing 32 nanorods
Researchers at PennState University have developed a simple modular chemical approach that could produce over 65,000 different types of complex nanorods. Here, electron microscope images are shown for 32 of these nanorods, which form with various combinations of materials. Each color represents a ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 27, 2020 Category: Science Source Type: video
Commercial fishing nets, lines, and ropes contribute to about half of all plastic waste
that ends up in our oceans. But, developing a degradable plastic with the mechanical strength comparable to commercial materials remains a difficult challenge. Chemists at Cornell University, with funding from ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 8, 2020 Category: Science Source Type: video
Male orchid bee
Researchers at the University of California, Davis, found that orchid bees, like this male, are easier to tell apart by the chemical differences of their perfumes than by their physical appearance.
[Research supported by National Science Foundation grant DEB 1457753.]
Learn more in the ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 21, 2020 Category: Science Source Type: video
Chemical compounds in male orchid bee ’ s perfume analyzed
Researchers at the University of California, Davis, used gas chromatography and mass spectrometry to separate and analyze each chemical compound in a male orchid bee’s (pictured) enticing perfume.
[Research supported by National Science Foundation grant DEB 1457753.]
Learn more in the ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 21, 2020 Category: Science Source Type: video
Investigating anti-viral chemicals that can be safely built into masks
This is an interview with Jiaxing Huang, professor of materials science and engineering at Northwestern University, and Birgit Schwenzer, a program director in NSF’s Division of Materials Research. Huang has received a rapid response research (RAPID) grant to investigate anti-viral chemicals that ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - May 8, 2020 Category: Science Source Type: video
