Direct Whole-Genome Sequencing of Cutaneous Strains of Haemophilus ducreyi
M. Marks et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - March 1, 2018 Category: Infectious Diseases Source Type: research
The Etiology of Genital Ulcer Disease and Coinfections With Chlamydia trachomatis and Neisseria gonorrhoeae in Zimbabwe: Results From the Zimbabwe STI Etiology Study
Background
In many countries, sexually transmitted infections (STIs) are treated syndromically. Thus, patients diagnosed as having genital ulcer disease (GUD) in Zimbabwe receive a combination of antimicrobials to treat syphilis, chancroid, lymphogranuloma venereum (LGV), and genital herpes. Periodic studies are necessary to assess the current etiology of GUD and assure the appropriateness of current treatment guidelines.
Materials and Methods
We selected 6 geographically diverse clinics in Zimbabwe serving high numbers of STI cases to enroll men and women with STI syndromes, including GUD. Sexually transmitted infect...
Source: Sexually Transmitted Diseases - January 1, 2018 Category: Sexual Medicine Tags: The Real World of STD Prevention Source Type: research
Macrolides for treatment of Haemophilus ducreyi infection in sexually active adults.
CONCLUSIONS: At present, the quality of the evidence on the effectiveness and safety of macrolides for treatment of H ducreyi infection in sexually active adults is low, implying that we are uncertain about the estimated treatment effect. There is no statistically significant difference between the available therapeutic alternatives for the treatment of sexually active adults with genital ulcers compatible with chancroid. Low quality evidence suggests that azithromycin could be considered as the first therapeutic alternative, based on their mono-dose oral administration, with a similar safety and effectiveness profile, whe...
Source: Cochrane Database of Systematic Reviews - December 11, 2017 Category: General Medicine Authors: Romero L, Huerfano C, Grillo-Ardila CF Tags: Cochrane Database Syst Rev Source Type: research
Usefulness and utility of NACO regime in the management of sexually transmitted infections: A pilot study
Conclusion: The present tool for validation of GUD-H can validate only 27% of cases. Overlap of etiologies is mostly common in vaginal discharge syndrome, wherein malignancies and premalignant conditions are overtreated with kits. Validation can be done only in two-third of cases with the available resources. However, syndromic approach provides the opportunity of treating STI without delay. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - November 24, 2017 Category: Dermatology Authors: Anupam Das Pramit Ghosh Ishita Ghosh Rittwika Bhattacharya Abul Kalam Azad Sardar Sebanti Goswami Debabrata Bandyopadhyay Nilay Kanti Das Source Type: research
Usefulness and utility of NACO regime in the management of sexually transmitted infections: A pilot study
Conclusion: The present tool for validation of GUD-H can validate only 27% of cases. Overlap of etiologies is mostly common in vaginal discharge syndrome, wherein malignancies and premalignant conditions are overtreated with kits. Validation can be done only in two-third of cases with the available resources. However, syndromic approach provides the opportunity of treating STI without delay. (Source: Indian Journal of Dermatology)
Source: Indian Journal of Dermatology - November 24, 2017 Category: Dermatology Authors: Anupam Das Pramit Ghosh Ishita Ghosh Rittwika Bhattacharya Abul Kalam Azad Sardar Sebanti Goswami Debabrata Bandyopadhyay Nilay Kanti Das Anupam Das Pramit Ghosh Ishita Ghosh Rittwika Bhattacharya Abul Kalam Azad Sardar Sebanti Goswami Debabrata Bandyopad Source Type: research
Sexually Transmitted Infections in Pakistan
BACKGROUND AND OBJECTIVES: Sexually transmitted infections (STIs) represent a major global health problem leading to morbidity, mortality and stigma. Prior to this study there was no information on the prevalence and knowledge of STIs in Faisalabad, Pakistan. DESIGN AND SETTING: Prospective, cross-sectional study in patients attending STI clinics from July 2006 to September 2009. PATIENTS AND METHODS: After obtaining consent, patients completed structured questionnaires used for behavioral surveys. Blood and urethral swabs were collected and tested for syphilis, gonococcus, genital herpes, chlamydia and chancroid...
Source: Annals of Saudi Medicine - November 21, 2017 Category: General Medicine Tags: ISSUE 3 Source Type: research
Gonorrhoea in Greenland, incidence and previous preventive measures: a review to improve future strategies.
Authors: Berntsen S, Karlsen APH, Pedersen ML, Mulvad G
Abstract
Gonorrhoea continues to be a significant health challenge in Greenland. The aim of this study was to describe the development of gonorrhoea in Greenland through time including incidence rates and previous measures taken to address the challenge. A systematic literature search in PubMed, Embase and The Cochrane Library was conducted. Furthermore, local archives were searched in the Health Clinic in Nuuk for relevant literature. From the 1940s the incidence of gonorrhoea increased steadily with a steep incline around 1970, possibly as a consequ...
Source: International Journal of Circumpolar Health - July 28, 2017 Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research
Evaluation of self-collected rectal swabs for the detection of bacteria responsible for sexually transmitted infections in a cohort of HIV-1-infected patients.
CONCLUSION: In conclusion, testing extra-genital sites is crucial for the diagnosis of STIs in men and women presenting or not concomitant urogenital infections in order to detect asymptomatic carriage with the aim of controlling and preventing transmission to their sexual partners.
PMID: 28590237 [PubMed - as supplied by publisher] (Source: Journal of Medical Microbiology)
Source: Journal of Medical Microbiology - June 8, 2017 Category: Microbiology Authors: Edouard S, Tamalet C, Tissot-Dupont H, Colson P, Ménard A, Ravaux I, Dhiver C, Tomei C, Stein A, Raoult D Tags: J Med Microbiol Source Type: research
< i > Haemophilus ducreyi < /i > DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea
Conclusions/SignificanceThis is the first time thatH.ducreyi DNA and colonization has been demonstrated on the skin of asymptomatic children and thatH.ducreyi DNA andT.p.pertenue DNA has been identified in flies and on fomites. The ubiquity ofH.ducreyi in the environment is a contributing factor to the spread of the organism. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - May 10, 2017 Category: Tropical Medicine Authors: Wendy Houinei Source Type: research
Skin diseases of the vulva: Infectious diseases.
Authors: Sand FL, Thomsen SF
Abstract
A multitude of infectious diseases of viral (genital herpes, herpes zoster, genital warts and molluscum contagiosum), bacterial (syphilis, chancroid, lymphogranuloma venereum, donovanosis, erysipelas, cellulitis and necrotising fasciitis, folliculitis, impetigo, bartholin gland abscess, trichomycosis and erythrasma), fungal (candidiasis and dermatophytosis) and parasitic (pediculosis pubis) origin may affect the vulvar area. Herein, we review the infections and their skin manifestations in the vulvar area.
PMID: 28397528 [PubMed - as supplied by publisher] (Sou...
Source: Journal of Obstetrics and Gynaecology - April 13, 2017 Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
< i > Haemophilus ducreyi < /i > Cutaneous Ulcer Strains Diverged from Both Class I and Class II Genital Ulcer Strains: Implications for Epidemiological Studies
Conclusions/SignificanceCU strains diverged from multiple lineages within both class I and class II GU strains. Multilocus sequence typing ofdsrA-hgbA-ncaA could be reliably used for epidemiological investigation of CU and GU strains. As class II strains grow relatively poorly and are relatively more susceptible to vancomycin than class I strains, these findings have implications for methods to recover CU strains. Comparison of contemporary CU and GU isolates would help clarify the relationship between these entities. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - December 26, 2016 Category: Tropical Medicine Authors: Dharanesh Gangaiah Source Type: research
Multiplex PCR testing for nine different sexually transmitted infections
Current sexually transmitted infection (STI) testing is not optimal due to delays in reporting or missed diagnoses due to a lack of comprehensive testing. The FilmArray® (BioFire Diagnostics, LLC, Salt Lake City, Utah) is a user-friendly, fully automated, multiplex PCR system that is being developed for rapid point-of-care use. A research-use-only STI panel including multiple PCR primer sets for each organism was designed to detect Chlamydia trachomatis, Neisseria gonorrhoeae, Treponema pallidum, Trichomonas vaginalis, Mycoplasma genitalium, Ureaplasma urealyticum, Haemophilus ducreyi, and herpes simplex virus (HSV) ty...
Source: International Journal of STD and AIDS - November 14, 2016 Category: Global & Universal Authors: Kriesel, J. D., Bhatia, A. S., Barrus, C., Vaughn, M., Gardner, J., Crisp, R. J. Tags: Original research articles Source Type: research
Sexually transmitted infections case notification rates in the Kingdom of Saudi Arabia, 2005 –2012
Conclusions: Nongonococcal urethritis, trichomoniasis, and HIV were the most commonly reported STIs in the Kingdom of Saudi Arabia. (Source: The Journal of Infection in Developing Countries)
Source: The Journal of Infection in Developing Countries - August 31, 2016 Category: Infectious Diseases Source Type: research
