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 Gardnerella vaginalis : Is it an Underestimated Cause of Urinary Symptoms in Males?
CONCLUSION: With the introduction of multiplex PCR tests, including those for G. vaginalis, we can expect a higher detection rate of these species of bacteria in male genitourinary samples, which could be the cause of unexplained urinary/urethral symptoms.PMID:38633399 | PMC:PMC10986695 | DOI:10.36519/idcm.2022.172 (Source: Herpes)
Source: Herpes - April 18, 2024 Category: Infectious Diseases Authors: Mert K ılıç Ye şim Beşli Ersin K öseoğlu Erhan Kerim Palao ğlu Tar ık Esen Source Type: research

Aetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study
Conclusion This study provided the acquisition of unprecedented data on the aetiology of UDS and GUD in Brazil, demonstrated the presence of a variety of pathogens in both sample types and reaffirmed the aetiologies known to be most prevalent globally. (Source: Sexually Transmitted Infections)
Source: Sexually Transmitted Infections - April 18, 2024 Category: Sexual Medicine Authors: Bazzo, M. L., Machado, H. d. M., Martins, J. M., Schörner, M. A., Buss, K., Barazzetti, F. H., Gaspar, P. C., Bigolin, A., Benzaken, A., de Carvalho, S. V. F., Andrade, L. d. F., Ferreira, W. A., Figueiroa, F., Fontana, R. M., da Silva, M. F. d. C Tags: Original research Source Type: research

AEDV Expert Document on the management of ulcerative venereal infections
Actas Dermosifiliogr. 2024 Mar 29:S0001-7310(24)00267-9. doi: 10.1016/j.ad.2024.03.021. Online ahead of print.ABSTRACTCurrently, ulcerative sexually transmitted infections, including syphilis, herpes simplex virus (HSV), lymphogranuloma venereum (LGV), chancroid, donovanosis and, more recently, monkeypox (MPOX), represent a growing challenge for health care professionals. The incidence of syphilis and LGV has increased in recent years in Spain. Additionally, HSV, syphilis and chancroid can also increase the risk of HIV acquisition and transmission. The population groups most vulnerable to these infections are young people,...
Source: Actas Dermo-Sifiliograficas - March 31, 2024 Category: Dermatology Authors: Caridad E Morales Francisco Montoya Nicol ás de Loredo Elena Sendagorta Source Type: research

AEDV Expert Document on the management of ulcerative venereal infections
Actas Dermosifiliogr. 2024 Mar 29:S0001-7310(24)00267-9. doi: 10.1016/j.ad.2024.03.021. Online ahead of print.ABSTRACTCurrently, ulcerative sexually transmitted infections, including syphilis, herpes simplex virus (HSV), lymphogranuloma venereum (LGV), chancroid, donovanosis and, more recently, monkeypox (MPOX), represent a growing challenge for health care professionals. The incidence of syphilis and LGV has increased in recent years in Spain. Additionally, HSV, syphilis and chancroid can also increase the risk of HIV acquisition and transmission. The population groups most vulnerable to these infections are young people,...
Source: Herpes - March 31, 2024 Category: Infectious Diseases Authors: Caridad E Morales Francisco Montoya Nicol ás de Loredo Elena Sendagorta Source Type: research

Aetiological molecular identification of sexually transmitted infections that cause urethral discharge syndrome and genital ulcer disease in Brazilian men: a nationwide study
CONCLUSION: This study provided the acquisition of unprecedented data on the aetiology of UDS and GUD in Brazil, demonstrated the presence of a variety of pathogens in both sample types and reaffirmed the aetiologies known to be most prevalent globally.PMID:38360847 | DOI:10.1136/sextrans-2023-055950 (Source: Herpes)
Source: Herpes - February 15, 2024 Category: Infectious Diseases Authors: Maria Luiza Bazzo Hanalydia de Melo Machado Jessica Motta Martins Marcos Andr é Schörner Ketlyn Buss Fernando Hartmann Barazzetti Pamela Cristina Gaspar Alisson Bigolin Adele Benzaken Simone Veloso Faria de Carvalho Lidiane da Fonseca Andrade William An Source Type: research

Prevalence and risk factors associated with Haemophilus ducreyi cutaneous ulcers in Cameroon
The objective of this study was to determine the prevalence ofHD as cause of cutaneous ulcers, investigate its presence in asymptomatic individuals and identify associated risk factors. A cross-sectional study was conducted in yaws endemic districts of Cameroon. Participants included people presenting yaws-like ulcers and asymptomatic individuals. Swab samples were collected from each participant and tested forHD andTreponema pallidum (TP) using an established qPCR method. Additionally, demographic, habitat, proximity, and hygiene characteristics were collected using a structured questionnaire. A total of 443 individuals p...
Source: PLoS Neglected Tropical Diseases - December 27, 2023 Category: Tropical Medicine Authors: Philippe Ndzomo Source Type: research

Sexually Transmitted Infections from the Twentieth to the Twenty-first Century
At the start of the 20 th century, we had little understanding of the size of the problem presented by what was then termed Venereal Diseases. Only gonorrhea, syphilis, and chancroid were recognized as being venereal in origin . Population surveys were available, but their accuracy is open to interpretation. For example, a serologic survey carried out in 1914 suggested that up to 12% of the adult men and 7% of the adult women of London suffered from syphilis. The rate of gonorrhea was thought to be even greater. (Source: Clinics in Dermatology)
Source: Clinics in Dermatology - December 25, 2023 Category: Dermatology Authors: Michael Adler Tags: Commentary Source Type: research

Dramatic Shift in the Etiology of Genital Ulcer Disease Among Patients Visiting a Sexually Transmitted Infections Clinic in Lilongwe, Malawi
CONCLUSIONS: We observed a dramatic increase in syphilis ulcer proportion in a population whose GUDs were previously HSV predominant. Observed differences in etiology and resolution by HIV status could play an important role in the ongoing transmission and treatment evaluation of GUD.PMID:37824787 | PMC:PMC10575672 | DOI:10.1097/OLQ.0000000000001853 (Source: Herpes)
Source: Herpes - October 12, 2023 Category: Infectious Diseases Authors: Jane S Chen Mitch M Matoga Claudia F Gaither Edward Jere Esther Mathiya Naomi Bonongwe Robert Krysiak Gabriel Banda Irving F Hoffman William C Miller Jonathan J Juliano Sarah E Rutstein Source Type: research

Dramatic Shift in the Etiology of Genital Ulcer Disease Among Patients Visiting a Sexually Transmitted Infections Clinic in Lilongwe, Malawi
CONCLUSIONS: We observed a dramatic increase in syphilis ulcer proportion in a population whose GUDs were previously HSV predominant. Observed differences in etiology and resolution by HIV status could play an important role in the ongoing transmission and treatment evaluation of GUD.PMID:37824787 | DOI:10.1097/OLQ.0000000000001853 (Source: Herpes)
Source: Herpes - October 12, 2023 Category: Infectious Diseases Authors: Jane S Chen Mitch M Matoga Claudia F Gaither Edward Jere Esther Mathiya Naomi Bonongwe Robert Krysiak Gabriel Banda Irving F Hoffman William C Miller Jonathan J Juliano Sarah E Rutstein Source Type: research

Endemic infectious cutaneous ulcers syndrome in the Oti Region of Ghana: Study of cutaneous leishmaniasis, yaws and Haemophilus ducreyi cutaneous ulcers
Conclusions/SignificanceThis study detected single and mixed occurrence of the causative organisms of CL, yaws, andH.ducreyi cutaneous ulcers in CL endemic communities of the Oti Region in Ghana. These findings emphasize the importance of integrating multiple skin diseases on a common research platform and calls for the development of a comprehensive guideline for diagnosing and treating tropical ulcers in the study areas. (Source: PLoS One)
Source: PLoS One - September 27, 2023 Category: Biomedical Science Authors: Richard Adjei Akuffo Source Type: research

Formate production is dispensable for Haemophilus ducreyi virulence in human volunteers
Infection and Immunity, Ahead of Print. (Source: Infection and Immunity)
Source: Infection and Immunity - August 18, 2023 Category: Infectious Diseases Authors: Julie A. Brothwell Kate R. Fortney Jalan S. Williams Teresa A. Batteiger Rory Duplantier Danielle Grounds Amber S. Jannasch Barry P. Katz Stanley M. Spinola 1 Department of Microbiology and Immunology, Indiana University School of Medicine , Indianapoli Source Type: research

Orthogonal Glycosylation with Phosphate Acceptors for Expeditious Synthesis of Bacterial Inner Core Oligosaccharides
We report a practical one-pot glycosylation strategy for synthesis of bacterial inner core oligosaccharides that composed of unavailable L-glycero-D--manno and D-glycero-D-manno-heptopyranose components. The glycosylation method features a new orthogonal glycosylation procedure; whereby a phosphate acceptor is coupled with a thioglycosyl donor producing a disaccharide phosphate, which can be engaged in another orthogonal glycosylation procedure to couple with a thioglycosyl acceptor. The phosphate acceptors used in above one-pot procedure are directly prepared from thioglycosyl acceptors via the in-situ phosphorylation. Su...
Source: Chemistry, an Asian Journal - June 20, 2023 Category: Chemistry Authors: I-Chen Lu Kuang-Chun Cheng Yi-Fang Wang Chia-Wei Pan Jan-Siang Hung Kwok-Kong Tony Mong Source Type: research