“The crackers challenge”: A reassuring low-dose gluten challenge in adults on gluten-free diet without proper diagnosis of coeliac disease
Gluten-free diet (GFD) is the one therapy in coeliac disease (CeD). Unfortunately, some patients adopt GFD before the diagnostic work-up. The guidelines suggest a 14-day gluten intake> 3 gr to get CeD diagnosis, although many subjects refuse this approach. Other evidence showed that the intake of 50 mg/day of gluten for 3 months could be useful for CeD diagnosis. (Source: Digestive and Liver Disease)
Source: Digestive and Liver Disease - March 23, 2024 Category: Gastroenterology Authors: Antonio Rispo, Alessia Dalila Guarino, Monica Siniscalchi, Nicola Imperatore, Antonella Santonicola, Simona Ricciolino, Roberto de Sire, Benedetta Toro, Nicola Mattia Cantisani, Carolina Ciacci Tags: Alimentary Tract Source Type: research
Association of autoimmune and allergic diseases with senile cataract: a bidirectional two-sample Mendelian randomization study
ConclusionsThe results of the MR analysis showed that there were causal relationships between type 1 diabetes, rheumatoid arthritis, hypothyroidism, systemic lupus erythematosus, asthma, allergic rhinitis and senile cataract. To clarify the possible role of autoimmune and allergy in the pathophysiology of senile cataract, further studies are needed. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 22, 2024 Category: Allergy & Immunology Source Type: research
